(Q41732524)

8 October 2017

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title

Selectivity and toxicity of antiarrhythmic drugs: molecular interactions with ion channels (English)

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8 October 2017

main subject

molecular interaction

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Katz AM

1

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8 October 2017

language of work or name

English

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publication date

1 February 1998

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American Journal of Medicine

8 October 2017

published in

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8 October 2017

volume

104

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8 October 2017

issue

2

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8 October 2017

page(s)

179-195

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Thromboembolic complications in atrial fibrillation

8 October 2017

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7 January 2021

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Gating for the physiologist

7 January 2021

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Molecular determinants of channel function

7 January 2021

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Structural parts involved in activation and inactivation of the sodium channel

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Cellular and molecular biology of voltage-gated sodium channels

7 January 2021

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Tracing the roots of ion channels

7 January 2021

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7 January 2021

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Voltage-dependent potentiation of L-type Ca2+ channels due to phosphorylation by cAMP-dependent protein kinase

7 January 2021

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Effects of protein phosphatase and kinase inhibitors on the cardiac L-type Ca current suggest two sites are phosphorylated by protein kinase A and another protein kinase

7 January 2021

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cAMP-dependent phosphorylation of two sites in the alpha subunit of the cardiac sodium channel.

7 January 2021

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Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif

7 January 2021

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Na+ channel subunits and Ig domains.

7 January 2021

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Activation of purified calcium channels by stoichiometric protein phosphorylation

7 January 2021

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Primary structure of the beta subunit of the DHP-sensitive calcium channel from skeletal muscle.

7 January 2021

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Alteration of ionic selectivity of a K+ channel by mutation of the H5 region

7 January 2021

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Mutations affecting internal TEA blockade identify the probable pore-forming region of a K+ channel.

7 January 2021

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Exchange of conduction pathways between two related K+ channels.

7 January 2021

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Molecular basis of permeation in voltage-gated ion channels

7 January 2021

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Existence of distinct sodium channel messenger RNAs in rat brain

7 January 2021

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Effects of III-IV linker mutations on human heart Na+ channel inactivation gating

7 January 2021

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On the molecular nature of the lidocaine receptor of cardiac Na+ channels. Modification of block by alterations in the alpha-subunit III-IV interdomain

7 January 2021

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Movement of the Na+ channel inactivation gate during inactivation.

7 January 2021

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Biophysical and molecular mechanisms of Shaker potassium channel inactivation

7 January 2021

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Putative receptor for the cytoplasmic inactivation gate in the Shaker K+ channel

7 January 2021

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NMR structure of inactivation gates from mammalian voltage-dependent potassium channels

7 January 2021

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Potassium channels and their evolving gates

7 January 2021

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Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShB.

7 January 2021

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Cloned neuronal IK(A) channels reopen during recovery from inactivation

7 January 2021

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SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

7 January 2021

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Molecular mechanism for an inherited cardiac arrhythmia

7 January 2021

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New revelations about the long-QT syndrome

7 January 2021

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Multiple mechanisms in the long-QT syndrome. Current knowledge, gaps, and future directions. The SADS Foundation Task Force on LQTS.

7 January 2021

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A Met-to-Val mutation in the skeletal muscle Na+ channel alpha-subunit in hyperkalaemic periodic paralysis

7 January 2021

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Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy.

7 January 2021

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Classes of calcium channels in vertebrate cells

7 January 2021

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Calcium channels, stores, and oscillations

7 January 2021

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Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells

7 January 2021

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Distinctive pharmacology and kinetics of cloned neuronal Ca2+ channels and their possible counterparts in mammalian CNS neurons.

7 January 2021

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Human neuronal voltage-dependent calcium channels: studies on subunit structure and role in channel assembly

7 January 2021

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L- and T-type calcium currents differ in finch and rat ventricular cardiomyocytes

7 January 2021

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Effect of postnatal development on calcium currents and slow charge movement in mammalian skeletal muscle

7 January 2021

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Post-natal disappearance of transient calcium channels in mouse skeletal muscle: effects of denervation and culture.

7 January 2021

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Diversity of calcium ion channels in cellular membranes

7 January 2021

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Development alters the expression of calcium currents in chick limb motoneurons.

7 January 2021

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Postnatal changes in T-type calcium current density in rat atrial myocytes

7 January 2021

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Cell cycle--dependent expression of L- and T-type Ca2+ currents in rat aortic smooth muscle cells in primary culture

7 January 2021

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Increase in T-type calcium current in atrial myocytes from adult rats with growth hormone-secreting tumors

7 January 2021

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T-type Ca2+ current is expressed in hypertrophied adult feline left ventricular myocytes

7 January 2021

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T-type Ca2+ channels are abnormal in genetically determined cardiomyopathic hamster hearts

7 January 2021

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Ca2+ influx via T-type channels modulates PDGF-induced replication of mouse fibroblasts

7 January 2021

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Endothelin-1 enhances calcium entry through T-type calcium channels in cultured neonatal rat ventricular myocytes

7 January 2021

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Mibefradil prevents neointima formation after vascular injury in rats. Possible role of the blockade of the T-type voltage-operated calcium channel

7 January 2021

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Simplified gene nomenclature

7 January 2021

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A Rosetta stone for K channels.

7 January 2021

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Potassium channels. Mixing and matching.

7 January 2021

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Homogeneity out of heterogeneity

7 January 2021

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Genetic approaches to cardiovascular disease. Supravalvular aortic stenosis, Williams syndrome, and long-QT syndrome

7 January 2021

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Missense mutation in the pore region of HERG causes familial long QT syndrome

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

A mutation in HERG associated with notched T waves in long QT syndrome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

A new wave for heart rhythms

7 January 2021

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Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes

7 January 2021

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An essential 'set' of K+ channels conserved in flies, mice and humans

7 January 2021

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Cloning and expression of an inwardly rectifying ATP-regulated potassium channel

7 January 2021

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Primary structure and functional expression of a mouse inward rectifier potassium channel

7 January 2021

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Characteristics of the delayed rectifier current (IKr and IKs) in canine ventricular epicardial, midmyocardial, and endocardial myocytes. A weaker IKs contributes to the longer action potential of the M cell

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Differences in transient outward currents of feline endocardial and epicardial myocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Regional variations in action potentials and transient outward current in myocytes isolated from rabbit left ventricle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Ionic bases for electrophysiological distinctions among epicardial, midmyocardial, and endocardial myocytes from the free wall of the canine left ventricle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

T wave changes persisting after ventricular pacing in canine heart are altered by 4-aminopyridine but not by lidocaine. Implications with respect to phenomenon of cardiac 'memory'

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Lipid-membrane interactions and the pathogenesis of ischemic damage in the myocardium

7 January 2021

1 reference

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The G-protein-gated atrial K+ channel IKACh is a heteromultimer of two inwardly rectifying K(+)-channel proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Molecular biology of voltage-dependent potassium channels

7 January 2021

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Molecular biology of voltage-gated K+ channels in heart

7 January 2021

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The inward rectification mechanism of the HERG cardiac potassium channel

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

The inconstancy of the human heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

The 'inner core' of inwardly rectifying K+ channels

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Cloning and functional expression of an inwardly rectifying K+ channel from human atrium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Cloning of a membrane protein that induces a slow voltage-gated potassium current

7 January 2021

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The protein IsK is a dual activator of K+ and Cl- channels.

7 January 2021

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Effect of the antiarrhythmic agent moricizine on survival after myocardial infarction

7 January 2021

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Enhanced functional expression of transient outward current in hypertrophied feline myocytes

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Chaos and physiology: deterministic chaos in excitable cell assemblies

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Possible molecular basis for the pharmacokinetics and pharmacodynamics of three membrane-active drugs: propranolol, nimodipine and amiodarone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Receptor sites for Ca2+ channel antagonists

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Antiarrhythmic agents: the modulated receptor mechanism of action of sodium and calcium channel-blocking drugs

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Combined effects of rate membrane potential, and drugs on maximum rate of rise (Vmax) of action potential upstroke of guinea pig papillary muscle

7 January 2021

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Differential Analysis of the Frequency-Dependent Effects of Class 1 Antiarrhythmic Drugs According to Periodical Ligand Binding

7 January 2021

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Classification and mechanism of action of antiarrhythmic drugs

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

Antiarrhythmic drug classifications. A critical appraisal of their history, present status, and clinical relevance

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2897%2900388-4

The Sicilian gambit. A new approach to the classification of antiarrhythmic drugs based on their actions on arrhythmogenic mechanisms. Task Force of the Working Group on Arrhythmias of the European Society of Cardiology

7 January 2021

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10.1016/S0002-9343(97)00388-4

7 January 2021

Identifiers

DOI

1 reference

8 October 2017

1 reference