(Q41734226)

8 October 2017

1 reference

title

In vivo model systems in P-glycoprotein-mediated multidrug resistance (English)

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8 October 2017

multiple drug resistance

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van de Vrie W

1

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8 October 2017

Marquet RL

2

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8 October 2017

Stoter G

3

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8 October 2017

De Bruijn EA

4

1 reference

8 October 2017

Eggermont AM

5

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8 October 2017

1 February 1998

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Critical Reviews in Clinical Laboratory Sciences

8 October 2017

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8 October 2017

35

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8 October 2017

1

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8 October 2017

1-57

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Biochemistry of multidrug resistance mediated by the multidrug transporter

8 October 2017

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

P-glycoprotein: clinical significance and methods of analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

How to probe clinical tumour samples for P-glycoprotein and multidrug resistance-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Expression of a multidrug-resistance gene in human tumors and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Expression of the multidrug resistance, MDR1, gene in neuroblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

MDR1 gene expression in solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

MDR1 gene expression and treatment outcome in acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Expression of the multidrug resistance gene in myeloid leukemias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

P-glycoprotein-mediated multidrug resistance in normal and neoplastic hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Clinical relevance of P-glycoprotein expression in haematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcoma of childhood

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

P-Glycoprotein Expression as a Predictor of the Outcome of Therapy for Neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

The effect of MDR-1 gene expression on outcome in acute myeloblastic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Multidrug resistance of DNA-mediated transformants is linked to transfer of the human mdr1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Sequence of mdr3 cDNA encoding a human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Cloning and characterization of a second member of the mouse mdr gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Identification of distinct P-glycoprotein gene sequences in rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Complete cDNA sequences encoding the Chinese hamster P-glycoprotein gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Duplication and evolution of the P-glycoprotein genes in pig.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Cloning and characterization of a member of the rat multidrug resistance (mdr) gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Identification of members of the P-glycoprotein multigene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

The gene encoding multidrug resistance is induced and expressed at high levels during pregnancy in the secretory epithelium of the uterus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Overexpression of the multidrug resistance gene mdr3 in spontaneous and chemically induced mouse hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Multidrug resistance and the role of P-glycoprotein knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

The tissue dependent expression of hamster P-glycoprotein genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Sex-dependent and independent expression of the P-glycoprotein isoforms in Chinese hamster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Structure and expression of the human MDR (P-glycoprotein) gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Cloning and regulation of the rat mdr2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Isolation of rat pgp3 cDNA: evidence for gender and zonal regulation of expression in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Activation of distinct multidrug-resistance (P-glycoprotein) genes during rat liver regeneration and hepatocarcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Induction of multidrug resistance gene expression during cholestasis in rats and nonhuman primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Decreased biotolerability for ivermectin and cyclosporin A in mice exposed to potent P-glycoprotein inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Cortisol is transported by the multidrug resistance gene product P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Multidrug resistance gene expression is controlled by steroid hormones in the secretory epithelium of the uterus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Reduced mRNA levels for the multidrug-resistance genes in cAMP-dependent protein kinase mutant cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Lack of correlation between mdr-1 expression and volume-activation of cloride-currents in rat colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

What have we learnt thus far from mice with disrupted P-glycoprotein genes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

The role of mdr2 P-glycoprotein in biliary lipid secretion. Cross-talk between cancer research and biliary physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Isolation and expression of a complementary DNA that confers multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Physical mapping, amplification, and overexpression of the mouse mdr gene family in multidrug-resistant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Differential over-expression of mdr1 genes in multidrug-resistant rat glioblastoma cell lines selected with doxorubicin or vincristine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Differential recognition of mdr1a and mdr1b gene products in multidrug resistant mouse tumour cell lines by different monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Functional analysis of P-glycoprotein mutants identifies predicted transmembrane domain 11 as a putative drug binding site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Human (MDR1) and mouse (mdr1, mdr3) P-glycoproteins can be distinguished by their respective drug resistance profiles and sensitivity to modulators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Structurally distinct MDR modulators show specific patterns of reversal against P-glycoproteins bearing unique mutations at serine939/941.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse mdr1 and mdr3 drug efflux pumps

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

The expression of P-glycoprotein in canine lymphoma and its association with multidrug resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

P-glycoprotein expression in canine lymphoma: a relevant, intermediate model of multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

P-glycoprotein drug efflux pump involved in the mechanisms of intrinsic drug resistance in various colon cancer cell lines. Evidence for a saturation of active daunorubicin transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Comparative study on reversal efficacy of SDZ PSC 833, cyclosporin A and verapamil on multidrug resistance in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Organ-specific modulation of steady-state mdr gene expression and drug resistance in murine colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

In vitro and in vivo chemosensitizing effect of cyclosporin A on an intrinsic multidrug-resistant rat colon tumour.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Multidrug resistance in rat colon carcinoma cell lines CC531, CC531mdr+ and CC531rev

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

P-glycoprotein expression and modulation of cell-membrane morphology in adriamycin-resistant P388 leukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Therapeutic efficacy of combination of antitumor agent with AHC-52 against multidrug-resistant cells in the intravenously inoculated P388 leukemia model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Induced multidrug resistance in murine leukemia L1210 and associated changes in a surface-membrane glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Reversal of the human and murine multidrug-resistance phenotype with megestrol acetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Regression of established tumors expressing P-glycoprotein by combinations of adriamycin, cyclosporin derivatives, and MRK-16 antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Establishment of drug resistance in human gastric and colon carcinoma xenograft lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Biochemical and pharmacological characterization of MCF-7 drug-sensitive and AdrR multidrug-resistant human breast tumor xenografts in athymic nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Identification of a multidrug resistance modulator with clinical potential by analysis of synergistic activity in vitro, toxicity in vivo and growth delay in a solid human tumour xenograft

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Development of an orthotopic SCID mouse-human tumor xenograft model displaying the multidrug-resistant phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Distribution and activity of doxorubicin combined with SDZ PSC 833 in mice with P388 and P388/DOX leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

SDZ PSC 833, a non-immunosuppressive cyclosporine: its potency in overcoming P-glycoprotein-mediated multidrug resistance of murine leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Reversal of Drug Resistance in a Human Colon Cancer Xenograft Expressing MDR1 Complementary DNA by In Vivo Administration of MRK-16 Monoclonal Antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

MDA435/LCC6 and MDA435/LCC6MDR1: ascites models of human breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Biochemical modulation of 'classical' multidrug resistance by BIBW22BS, a potent derivative of dipyridamole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Membrane-Mediated Drug Resistance and Phenotypic Reversion to Normal Growth Behavior of Chinese Hamster Cells 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Establishment and in vivo characterization of multidrug-resistant dunning R3327 rat prostate-carcinoma cell-lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

In vivo characterization of a doxorubicin resistant B16 melanoma cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Human tumor xenografts as model for drug testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Expression of a human multidrug resistance cDNA (MDR1) in the bone marrow of transgenic mice: resistance to daunomycin-induced leukopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Transgenic mice that express the human multidrug-resistance gene in bone marrow enable a rapid identification of agents that reverse drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Pharmacological considerations in the modulation of multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Modulation by verapamil of vincristine pharmacokinetics and toxicity in mice bearing human tumor xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Pharmacologic interactions between the resistance-modifying cyclosporine SDZ PSC 833 and etoposide (VP 16-213) enhance in vivo cytostatic activity and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Altered pharmacokinetics of vinblastine in Mdr1a P-glycoprotein-deficient Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Inhibition of intestinal P-glycoprotein and effects on etoposide absorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Effect of cyclosporine on colchicine secretion by a liver canalicular transporter studied in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Inhibition of etoposide elimination in the isolated perfused rat liver by Cremophor EL and Tween 80.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Experimental reversal of P-glycoprotein-mediated multidrug resistance by pharmacological chemosensitisers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

SDZ 280-446, a novel semi-synthetic cyclopeptolide: in vitro and in vivo circumvention of the P-glycoprotein-mediated tumour cell multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Modulation of multidrug resistance by SDZ PSC 833 in leukemic and solid-tumor-bearing mouse models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Effects of verapamil on chronic doxorubicin-induced cardiotoxicity in dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Effects of verapamil on the acute toxicity of doxorubicin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

The chemosensitizer cyclosporin A enhances the toxic side-effects of doxorubicin in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Myeloid and lymphoid cell alterations in normal mice exposed to chemotherapy with doxorubicin and/or the multidrug-resistance reversing agent SDZ PSC 833.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Increased effectiveness of liposome-encapsulated doxorubicin in multidrug-resistant-transgenic mice compared with free doxorubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Inhibition of multidrug-resistant human tumor growth in athymic mice by anti-P-glycoprotein monoclonal antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Enhancement by recombinant human interferon alfa of the reversal of multidrug resistance by MRK-16 monoclonal antibody.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Transfer and expression of the human multiple drug resistance gene into live mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Transfer of the MDR1 gene into haematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Prediction of response to drug therapy of cancer. A review of in vitro assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Antineoplastic drug screening belongs in the laboratory, not in the clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Modulation of multidrug-resistant multiple myeloma by cyclosporin. The Leukaemia Group of the EORTC and the HOVON

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

A phase II study of epidoxorubicin in colorectal cancer and the use of cyclosporin-A in an attempt to reverse multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Phase II study of combining vinblastine and cyclosporin-A to circumvent multidrug resistance in renal cell cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Clinical trials of P-glycoprotein reversal in solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Reversal of multidrug resistance in acute myeloid leukaemia and other haematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

Cyclosporin A corrects daunorubicin resistance in Ehrlich ascites carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

P-glycoprotein gene amplification and expression in multidrug-resistant murine P388 and B16 cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408369891234165

10.1080/10408369891234165

21 January 2018

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