(Q41749968)

8 October 2017

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title

Pharmacology of glutamate receptor antagonists in the kindling model of epilepsy (English)

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8 October 2017

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Löscher W

1

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8 October 2017

1 April 1998

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8 October 2017

Progress in Neurobiology

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8 October 2017

54

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8 October 2017

6

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8 October 2017

721-741

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Does kindling model anything clinically relevant?

8 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Long-lasting enhancement of metabotropic excitatory amino acid receptor-mediated polyphosphoinositide hydrolysis in the amygdala/ pyriform cortex of deep prepiriform cortical kindled rats

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Kindling induces a long-lasting increase in brain nitric oxide synthase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Blockade of both epileptogenesis and glutamate release by (1S,3S)-ACPD, a presynaptic glutamate receptor agonist

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Review: neurotransmitter receptors. II. AMPA and kainate receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Metabotropic glutamate receptors: an original family of G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Glutamate, GABA and epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Antagonists of the NMDA receptor-channel complex and motor coordination.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Anticonvulsant activity of a novel NMDA/glycine site antagonist, MDL 104,653, against kindled and sound-induced seizures

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Weak anticonvulsant activity of CGP 37849 and CGP 39551 against kindled seizures following systemic administration

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Competitive NMDA receptor antagonists raise electrically kindled generalized seizure thresholds

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

7-Chlorokynurenic acid, a strychnine-insensitive glycine receptor antagonist, inhibits limbic seizure kindling

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Excitatory amino acid receptors in epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

The effect of the non-NMDA receptor antagonist GYKI 52466 and NBQX and the competitive NMDA receptor antagonist D-CPPene on the development of amygdala kindling and on amygdala-kindled seizures.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Kindled rats are more sensitive than non-kindled rats to the behavioural effects of combined treatment with MK-801 and valproate

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Anticonvulsant effects by combined treatment with a glycineB receptor antagonist and a polyamine site antagonist in amygdala-kindled rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Dextromethorphan, a common antitussive, reduces kindled amygdala seizures in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Combined blockade of NMDA and non-NMDA receptors produces respiratory arrest in the adult cat

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Glutamate, nitric oxide and cell-cell signalling in the nervous system

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https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

The NMDA-receptor antagonist, MK-801, suppresses limbic kindling and kindled seizures.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

The NMDA antagonist MK-801 suppresses behavioral seizures, augments afterdischarges, but does not block development of perforant path kindling

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

A permanent change in brain function resulting from daily electrical stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

The N-methyl-D-aspartate antagonists aminophosphonovalerate and carboxypiperazinephosphonate retard the development and expression of kindled seizures

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Loss of mGluR-mediated hyperpolarizations and increase in mGluR depolarizations in basolateral amygdala neurons in kindling-induced epilepsy.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Sex differences in NMDA receptor mediated responses in rats.

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https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

NMDA receptors and in vivo dopamine release in the nucleus accumbens and caudatus.

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https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

A novel non-NMDA receptor antagonist shows selective displacement of low-affinity [3H]kainate binding.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Ionotropic glutamate receptors--focus on non-NMDA receptors

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https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

The glycine site of the NMDA receptor--five years on.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Kindling induces the long-lasting expression of a novel population of NMDA receptors in hippocampal region CA3.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Excitatory effects of kynurenine and its metabolites, amino acids and convulsants administered into brain ventricles: differences between rats and mice

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Glutamate receptors of the kainate type and synaptic transmission

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Prospects for clinically tolerated NMDA antagonists: open-channel blockers and alternative redox states of nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Evaluation of CPP, a selective NMDA antagonist, in various rodent models of epilepsy. Comparison with other NMDA antagonists, and with diazepam and phenobarbital.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

The receptor antagonist MK-801 induces increases in dopamine and serotonin metabolism in several brain regions of rats

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Comparison of competitive and uncompetitive NMDA receptor antagonists with regard to monoaminergic neuronal activity and behavioural effects in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Low doses of NMDA receptor antagonists synergistically increase the anticonvulsant effect of the AMPA receptor antagonist NBQX in the kindling model of epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Anticonvulsant effects of the glycine/NMDA receptor ligands D-cycloserine and D-serine but not R-(+)-HA-966 in amygdala-kindled rats

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

New visions in the pharmacology of anticonvulsion

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https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

High doses of memantine (1-amino-3,5-dimethyladamantane) induce seizures in kindled but not in non-kindled rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Responses to NMDA receptor antagonists altered by epileptogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Differences in anticonvulsant potency and adverse effects between dextromethorphan and dextrorphan in amygdala-kindled and non-kindled rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Effects of the competitive NMDA receptor antagonist, CGP 37849, on anticonvulsant activity and adverse effects of valproate in amygdala-kindled rats

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Over-additive anticonvulsant effect of memantine and NBQX in kindled rats

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Strategies in antiepileptic drug development: is rational drug design superior to random screening and structural variation?

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Potentiation of MK-801-induced breathing impairment by 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Anticonvulsant and antiepileptogenic actions of MK-801 in the kindling and electroshock models

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Cellular and molecular basis of epilepsy.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Excitatory amino acids in epilepsy and potential novel therapies

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Effects of MK-801 on spontaneous and amphetamine-stimulated dopamine release in striatum measured with in vivo microdialysis in awake rats

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Effects of competitive and noncompetitive NMDA receptor antagonists on kindling and LTP

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Antiepileptogenic action of 7-chlorokynurenic acid on amygdala kindling of rats

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Antiepileptogenic and anticonvulsant effects of NBQX, a selective AMPA receptor antagonist, in the rat kindling model of epilepsy.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Epileptogenesis in vivo enhances the sensitivity of inhibitory presynaptic metabotropic glutamate receptors in basolateral amygdala neurons in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders?

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Is GABA release modulated by presynaptic excitatory amino acid receptors?

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Modification of seizure activity by electrical stimulation. II. Motor seizure

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3-benzodiazepines

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Phenytoin potently increases the threshold for focal seizures in amygdala-kindled rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Anticonvulsant activity of antagonists and partial agonists for the NMDA receptor-associated glycine site in the kindling model of epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Dose-dependent anticonvulsant and proconvulsant effects of nitric oxide synthase inhibitors on seizure threshold in a cortical stimulation model in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Anticonvulsant action of a non-competitive antagonist of NMDA receptors (MK-801) in the kindling model of epilepsy.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Kindling: basic mechanisms and clinical validity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Competitive NMDA receptor antagonists do not block cholinergic kindling with carbachol

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

The evaluation and treatment of seizures

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

The TINS/TiPS Lecture. The molecular biology of mammalian glutamate receptor channels

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Subtypes of NMDA receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Anticonvulsant action of metabotropic glutamate receptor agonists in kindled amygdala of rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

The excitatory amino acid antagonist D-CPP-ene (SDZ EAA-494) in patients with epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Effects of dextromethorphan, a nonopioid antitussive, on development and expression of amygdaloid kindled seizures.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Intracerebral 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) produces limbic seizures that are not blocked by ionotropic glutamate receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Epilepsy and behaviour

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Influence of MK-801 on the anticonvulsant activity of antiepileptics.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Antiparkinsonian drugs memantine and trihexyphenidyl potentiate the anticonvulsant activity of valproate against maximal electroshock-induced seizures

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Selective block of recombinant glur6 receptors by NS-102, a novel non-NMDA receptor antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

1 reference

7 January 2021

Effect of carbamazepine, oxcarbazepine and lamotrigine on the increase in extracellular glutamate elicited by veratridine in rat cortex and striatum.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

The impact of a competitive and a non-competitive NMDA receptor antagonist on dopaminergic neurotransmission in the rat ventral tegmental area and substantia nigra.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

The effect of MK-801 on kindled seizures: implications for use and limitations as an antiepileptic drug

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Low doses of the glycine/NMDA receptor antagonist R-(+)-HA-966 but not D-cycloserine induce paroxysmal activity in limbic brain regions of kindled rats

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Anticonvulsant effects of eliprodil alone or combined with the glycineB receptor antagonist L-701,324 or the competitive NMDA antagonist CGP 40116 in the amygdala kindling model in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Weak anticonvulsant effects of two novel glycineB receptor antagonists in the amygdala-kindling model in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

Effects of the NMDA receptor antagonist MK-801 against amygdaloid-kindled seizures in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

The competitive NMDA antagonist, D-CPP-ene, potentiates the anticonvulsant activity of conventional antiepileptics against maximal electroshock-induced seizures in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2897%2900092-0

7 January 2021

10.1016/S0301-0082(97)00092-0

Identifiers

DOI

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8 October 2017

1 reference

PubMed ID

9560847