(Q41752514)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9564176%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

review article

1 reference

title

Leptin, leptin receptors, and the control of body weight (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9564176%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Leptin, Leptin Receptors, and the Control of Body Weight (English)

1 reference

https://api.crossref.org/works/10.1111/J.1753-4887.1998.TB01685.X

19 December 2024

main subject

cell surface receptor

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9564176

19 December 2024

author name string

J. M. Friedman

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9564176

19 December 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9564176

19 December 2024

publication date

1 February 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9564176%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

February 1998

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9564176

full work available at URL

19 December 2024

https://academic.oup.com/nutritionreviews/article-pdf/56/suppl_1/S38/24089382/nutritionreviews56-s038.pdf

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9564176

http://academic.oup.com/nutritionreviews/article-pdf/56/suppl_1/S38/8393934/nutritionreviews56-s038.pdf

19 December 2024

1 reference

https://api.crossref.org/works/10.1111/J.1753-4887.1998.TB01685.X

19 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9564176%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

volume

56

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9564176%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

issue

2 Pt 2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9564176%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

page(s)

s38-46; discussion s54-75

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9564176%20AND%20SRC:MED&resulttype=core&format=json

Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

11 November 2019

cites work

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Tackling a weighty problem

19 December 2024

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The effects of lesions in the hypothalamus in parabiotic rats

19 December 2024

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Positional cloning of the mouse obese gene and its human homologue

19 December 2024

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Abnormal splicing of the leptin receptor in diabetic mice

19 December 2024

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Identification and expression cloning of a leptin receptor, OB-R

19 December 2024

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Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

19 December 2024

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The molecular basis of the obese mutation in ob2J mice

19 December 2024

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Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus

19 December 2024

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Weight-reducing effects of the plasma protein encoded by the obese gene

19 December 2024

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Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

19 December 2024

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Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

19 December 2024

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Effects of the obese gene product on body weight regulation in ob/ob mice

19 December 2024

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Decreased food intake does not completely account for adiposity reduction after ob protein infusion

19 December 2024

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Recombinant ob protein reduces feeding and body weight in the ob/ob mouse

19 December 2024

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The role of neuropeptide Y in the antiobesity action of the obese gene product

19 December 2024

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Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin

19 December 2024

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Physiological response to long-term peripheral and central leptin infusion in lean and obese mice

19 December 2024

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Human leptin characterization

19 December 2024

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Crystal structure of the obese protein leptin-E100

19 December 2024

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Threading analysis suggests that the obese gene product may be a helical cytokine

19 December 2024

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A human leptin mutant induces weight gain in normal mice

19 December 2024

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Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting

19 December 2024

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Evidence for leptin binding to proteins in serum of rodents and humans: modulation with obesity

19 December 2024

25

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Role of leptin in the neuroendocrine response to fasting

19 December 2024

26

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The alphabet of weight control

19 December 2024

27

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Role of melanocortinergic neurons in feeding and the agouti obesity syndrome

19 December 2024

28

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Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y.

19 December 2024

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Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes

19 December 2024

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Serum immunoreactive-leptin concentrations in normal-weight and obese humans

19 December 2024

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Human leptin levels are pulsatile and inversely related to pituitary-adrenal function.

19 December 2024

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Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters

19 December 2024

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Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia

19 December 2024

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Transient increase in obese gene expression after food intake or insulin administration

19 December 2024

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High leptin concentrations in serum of very obese children are further stimulated by dexamethasone

19 December 2024

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Glucocorticoids as counterregulatory hormones of leptin: toward an understanding of leptin resistance

19 December 2024

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Thiazolidinediones repress ob gene expression in rodents via activation of peroxisome proliferator-activated receptor gamma

19 December 2024

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Transcriptional activation of the mouse obese (ob) gene by CCAAT/enhancer binding protein alpha

19 December 2024

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The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression

19 December 2024

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Defective STAT signaling by the leptin receptor in diabetic mice

19 December 2024

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Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization

19 December 2024

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Leptin receptor mutations in 129 db3J/db3J mice and NIH facp/facp rats

19 December 2024

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Leptin receptor missense mutation in the fatty Zucker rat.

19 December 2024

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Phenotype of fatty due to Gln269Pro mutation in the leptin receptor (Lepr).

19 December 2024

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Nonsense mutation of leptin receptor in the obese spontaneously hypertensive Koletsky rat

19 December 2024

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19 December 2024

The leptin receptor

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A short form of leptin receptor performs signal transduction

19 December 2024

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Dimerization of the extracellular domain of granuloycte-colony stimulating factor receptor by ligand binding: a monovalent ligand induces 2:2 complexes

19 December 2024

52

1 reference

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Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

19 December 2024

53

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

19 December 2024

54

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Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.

19 December 2024

55

1 reference

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Localization of leptin receptor mRNA splice variants in murine peripheral tissues by RT-PCR and in situ hybridization

19 December 2024

56

1 reference

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Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization

19 December 2024

57

1 reference

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The effect of leptin is enhanced by microinjection into the ventromedial hypothalamus.

19 December 2024

59

1 reference

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Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans

19 December 2024

60

1 reference

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Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance

19 December 2024

61

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Human blood-brain barrier leptin receptor. Binding and endocytosis in isolated human brain microvessels

19 December 2024

62

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Leptin enters the brain by a saturable system independent of insulin

19 December 2024

63

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Receptor-mediated peptide transport through the blood-brain barrier

19 December 2024

64

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Modulation of insulin activities by leptin

19 December 2024

65

1 reference

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Leptin induces tyrosine phosphorylation of cellular proteins including STAT-1 in human renal adenocarcinoma cells, ACHN.

19 December 2024

66

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Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells.

19 December 2024

67

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Role of leptin in fat regulation

19 December 2024

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Leptin stimulates glucose transport and glycogen synthesis in C2C12 myotubes: evidence for a P13-kinase mediated effect

19 December 2024

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Leptin impairs metabolic actions of insulin in isolated rat adipocytes.

19 December 2024

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Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity

19 December 2024

71

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Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action

19 December 2024

72

1 reference

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Diet-induced obese mice develop peripheral, but not central, resistance to leptin

19 December 2024

73

1 reference

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Targeted disruption of the melanocortin-4 receptor results in obesity in mice

19 December 2024

75

1 reference

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Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity

19 December 2024

76

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Impaired processing of brain proneurotensin and promelanin-concentrating hormone in obese fat/fat mice

19 December 2024

77

1 reference

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Identification and characterization of the mouse obesity gene tubby: a member of a novel gene family

19 December 2024

78

1 reference

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A candidate gene for the mouse mutation tubby

19 December 2024

79

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The hypothalamus, intrinsic connections and outflow pathways to the endocrine system in relation to the control of feeding and metabolism

19 December 2024

80

1 reference

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Serum leptin levels in the acquired immunodeficiency syndrome

19 December 2024

81

1 reference

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Serum immunoreactive leptin concentrations in patients with anorexia nervosa before and after partial weight recovery

19 December 2024

82

1 reference

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Relatively low plasma leptin concentrations precede weight gain in Pima Indians

19 December 2024

83

1 reference

https://api.crossref.org/works/10.1111/J.1753-4887.1998.TB01685.X

Absence of mutations in the human OB gene in obese/diabetic subjects

19 December 2024

84

1 reference

https://api.crossref.org/works/10.1111/J.1753-4887.1998.TB01685.X

Obese (ob) gene defects are rare in human obesity

19 December 2024

85

1 reference

https://api.crossref.org/works/10.1111/J.1753-4887.1998.TB01685.X

Congenital leptin deficiency is associated with severe early-onset obesity in humans

19 December 2024

86

1 reference

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OB gene not linked to human obesity in Mexican American affected sib pairs from Starr County, Texas

19 December 2024

87

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Indication for linkage of the human OB gene region with extreme obesity

19 December 2024

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Extreme obesity may be linked to markers flanking the human OB gene

19 December 2024

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The hypothalamic leptin receptor in humans: identification of incidental sequence polymorphisms and absence of the db/db mouse and fa/fa rat mutations

19 December 2024

90

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Stimulation of corticotrophin-releasing hormone release by the obese (ob) gene product, leptin, from hypothalamic explants.

19 December 2024

93

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Identification of targets of leptin action in rat hypothalamus

19 December 2024

94

1 reference

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19 December 2024

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9564176%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference