(Q41756358)

8 October 2017

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title

Regulation of gene expression, growth, and cell survival by IL-4: contribution of multiple signaling pathways (English)

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8 October 2017

Keegan AD

1

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8 October 2017

Zamorano J

series ordinal

2

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8 October 2017

language of work or name

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1 March 1998

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8 October 2017

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8 October 2017

volume

8

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8 October 2017

issue

1

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8 October 2017

page(s)

1-13

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https://scigraph.springernature.com/pub.10.1038/cr.1998.1

8 October 2017

exact match

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cites work

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Receptors for B-cell stimulatory factor-1 expressed on cells of haematopoietic lineage

21 January 2018

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Characterization of the high-affinity cell-surface receptor for murine B-cell-stimulating factor 1

21 January 2018

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The murine interleukin-4 receptor: molecular cloning and characterization of secreted and membrane bound forms.

21 January 2018

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Expression cloning of a cDNA encoding the murine interleukin 4 receptor based on ligand binding

21 January 2018

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Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily

21 January 2018

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Molecular cloning of a cDNA encoding the human interleukin 4 receptor

21 January 2018

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The hematopoietin receptor superfamily

21 January 2018

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The murine interleukin-4 receptor gene: genomic structure, expression and potential for alternative splicing

21 January 2018

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Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor

21 January 2018

1 reference

Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor

21 January 2018

1 reference

cDNA cloning and characterization of the human interleukin 13 receptor alpha chain

21 January 2018

1 reference

Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha chain

21 January 2018

1 reference

Cytokine receptor signalling

21 January 2018

1 reference

Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits

21 January 2018

1 reference

Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

21 January 2018

1 reference

Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

21 January 2018

1 reference

Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2.

21 January 2018

1 reference

Receptors for interleukin (IL)-4 do not associate with the common gamma chain, and IL-4 induces the phosphorylation of JAK2 tyrosine kinase in human colon carcinoma cells

21 January 2018

1 reference

Interleukin-13 signal transduction in lymphohemopoietic cells. Similarities and differences in signal transduction with interleukin-4 and insulin

21 January 2018

1 reference

The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15.

21 January 2018

1 reference

Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways.

21 January 2018

1 reference

Jak1 expression is required for mediating interleukin-4-induced tyrosine phosphorylation of insulin receptor substrate and Stat6 signaling molecules

21 January 2018

1 reference

Activation of JAK3, but not JAK1, is critical to interleukin-4 (IL4) stimulated proliferation and requires a membrane-proximal region of IL4 receptor alpha.

21 January 2018

1 reference

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 January 2018

1 reference

An interleukin-4-induced transcription factor: IL-4 Stat

21 January 2018

1 reference

Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis

21 January 2018

1 reference

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

21 January 2018

1 reference

The IRS-2 gene on murine chromosome 8 encodes a unique signaling adapter for insulin and cytokine action.

21 January 2018

1 reference

Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohemopoietic cells

21 January 2018

1 reference

Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases

21 January 2018

1 reference

The critical region in the cytoplasmic domain of human IL-4 receptor for induction of IgE synthesis

21 January 2018

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Common elements in interleukin 4 and insulin signaling pathways in factor-dependent hematopoietic cells.

21 January 2018

1 reference

PTB domains of IRS-1 and Shc have distinct but overlapping binding specificities

21 January 2018

1 reference

Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain

21 January 2018

1 reference

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

21 January 2018

1 reference

Essential role of Stat6 in IL-4 signalling

21 January 2018

1 reference

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

21 January 2018

1 reference

Defective STAT signaling by the leptin receptor in diabetic mice

21 January 2018

1 reference

Stat6 and Jak1 are common elements in platelet-derived growth factor and interleukin-4 signal transduction pathways in NIH 3T3 fibroblasts

21 January 2018

1 reference

The non-histone chromosomal protein HMG-I(Y) contributes to repression of the immunoglobulin heavy chain germ-line epsilon RNA promoter

21 January 2018

1 reference

Interleukin 4-inducible phosphorylation of HMG-I(Y) is inhibited by rapamycin

21 January 2018

1 reference

PI3K: downstream AKTion blocks apoptosis

21 January 2018

1 reference

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4

21 January 2018

1 reference

Interleukin 4 protects chronic lymphocytic leukemic B cells from death by apoptosis and upregulates Bcl-2 expression

21 January 2018

1 reference

Growth factors can enhance lymphocyte survival without committing the cell to undergo cell division

21 January 2018

1 reference

Interleukin 4 activates human B lymphocytes via transient inositol lipid hydrolysis and delayed cyclic adenosine monophosphate generation

21 January 2018

1 reference

7 January 2021

Interleukin 4 receptor: signaling mechanisms

1 reference

7 January 2021

Interleukin-4-specific signal transduction events are driven by homotypic interactions of the interleukin-4 receptor alpha subunit.

1 reference

7 January 2021

Allergy-associated I epsilon and Ec epsilon receptor II (CD23b) genes activated via binding of an interleukin-4-induced transcription factor to a novel responsive element

1 reference

7 January 2021

Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4

1 reference

7 January 2021

Role of IRS-2 in insulin and cytokine signalling

1 reference

7 January 2021

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

1 reference

7 January 2021

IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells

1 reference

7 January 2021

An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth

1 reference

7 January 2021

IL-4 function can be transferred to the IL-2 receptor by tyrosine containing sequences found in the IL-4 receptor alpha chain

1 reference

7 January 2021

Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor

1 reference

7 January 2021

HMG-I(Y) phosphorylation status as a nuclear target regulated through insulin receptor substrate-1 and the I4R motif of the interleukin-4 receptor

1 reference

7 January 2021

Expression of bcl-x during mouse B cell differentiation and following activation by various stimuli

1 reference

7 January 2021

Identifiers

DOI

10.1038/CR.1998.1

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Dimensions Publication ID

8 October 2017

1037447578

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