(Q41761005)

English

Assessment of the effect of dextromethorphan and ketamine on the acute nociceptive threshold and wind-up of the second pain response in healthy male volunteers

scientific article published on June 2002

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Assessment of the effect of dextromethorphan and ketamine on the acute nociceptive threshold and wind-up of the second pain response in healthy male volunteers (English)

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

author name string

A M Hughes

1

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

J Rhodes

2

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

G Fisher

3

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

M Sellers

4

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

J W Growcott

5

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

language of work or name

0 references

publication date

1 June 2002

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

British Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

53

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

6

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

604-612

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Targeting the N-methyl-D-aspartate receptor for chronic pain management. Preclinical animal studies, recent clinical experience and future research directions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

NMDA-receptor antagonists in neuropathic pain: experimental methods to clinical trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

Update on the neurophysiology of pain transmission and modulation: focus on the NMDA-receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

The effects of ketamine on the temporal summation (wind-up) of the R(III) nociceptive flexion reflex and pain in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

Efficacy of pharmacological treatments of neuropathic pain: an update and effect related to mechanism of drug action.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

Use and efficacy of low-dose ketamine in the management of acute postoperative pain: a review of current techniques and outcomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

Ketamine: teaching an old drug new tricks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

Ketamine, an NMDA receptor antagonist, suppresses spatial and temporal properties of burn-induced secondary hyperalgesia in man: a double-blind, cross-over comparison with morphine and placebo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

High-dose oral dextromethorphan versus placebo in painful diabetic neuropathy and postherpetic neuralgia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

Effect of systemic N-methyl-D-aspartate receptor antagonist (ketamine) on primary and secondary hyperalgesia in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

Dextrorphan relieves neuropathic heat-evoked hyperalgesia in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

The role of excitatory amino acid receptors and intracellular messengers in persistent nociception after tissue injury in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

Dextromethorphan for the treatment of neuropathic pain: a double-blind randomised controlled crossover trial with integral n-of-1 design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

Relief of post-herpetic neuralgia with the N-methyl-D-aspartic acid receptor antagonist ketamine: a double-blind, cross-over comparison with morphine and placebo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

Comparison of ketamine and pethidine in experimental and postoperative pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

Evidence for involvement of N-methylaspartate receptors in 'wind-up' of class 2 neurones in the dorsal horn of the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

Phenotypic differences in dextromethorphan metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

An open label trial of dextromethorphan in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

A cure for wind up: NMDA receptor antagonists as potential analgesics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

Evidence for spinal N-methyl-D-aspartate receptor involvement in prolonged chemical nociception in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

Neurogenic hyperalgesia: psychophysical studies of underlying mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

The induction and maintenance of central sensitization is dependent on N -methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

Dextromethorphan. An overview of safety issues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

Peripheral suppression of first pain and central summation of second pain evoked by noxious heat pulses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

6 June 2018

A randomized, controlled trial of high-dose dextromethorphan in facial neuralgias.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

18 August 2018

Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

18 August 2018

Effects of intravenous ketamine, alfentanil, or placebo on pain, pinprick hyperalgesia, and allodynia produced by intradermal capsaicin in human subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

18 August 2018

Intrathecal treatment with dextrorphan or ketamine potently reduces pain-related behaviors in a rat model of peripheral mononeuropathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

18 August 2018

The N-methyl-D-aspartate receptor antagonist dextromethorphan selectively reduces temporal summation of second pain in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

18 August 2018

Central nervous system effects of subdissociative doses of (S)-ketamine are related to plasma and brain concentrations measured with positron emission tomography in healthy volunteers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

18 August 2018

Pharmacokinetics and analgesic effect of ketamine in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

18 August 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2125.2002.01602.X

21 January 2018

Ethical guidelines for pain research in humans. Committee on Ethical Issues of the International Association for the Study of Pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874339

2 December 2018

Pathophysiology of pain

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2125.2002.01602.X

21 January 2018

Pain, hyperalgesia and activity in nociceptive C units in humans after intradermal injection of capsaicin

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2125.2002.01602.X

21 January 2018

Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following C fibre stimulation

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2125.2002.01602.X

21 January 2018

Quantitative assessment of thermal and pain sensitivity

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2125.2002.01602.X

21 January 2018

Inhibition of the 5-HT(1A) receptor-mediated inwardly rectifying K(+) current by dextromethorphan in rat dorsal raphe neurones

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2125.2002.01602.X

21 January 2018

NMDA receptor antagonists enhance 5-HT2 receptor-mediated behavior, head-twitch response, in mice

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2125.2002.01602.X

21 January 2018

Pharmacokinetics of dextromethorphan and dextrorphan: a single dose comparison of three preparations in human volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/12047485

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic comparison of a dextromethorphan-salbutamol combination tablet and a plain dextromethorphan tablet

1 reference

https://pubmed.ncbi.nlm.nih.gov/12047485

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of temporal summation of second pain sensations elicited by brief contact of glabrous skin by a preheated thermode

1 reference

https://pubmed.ncbi.nlm.nih.gov/12047485

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.1365-2125.2002.01602.X

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

ResearchGate publication ID

0 references

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