(Q41775640)

English

Propranolol oxidation by human liver microsomes--the use of cumene hydroperoxide to probe isoenzyme specificity and regio- and stereoselectivity

scientific article published on November 1990

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Propranolol oxidation by human liver microsomes--the use of cumene hydroperoxide to probe isoenzyme specificity and regio- and stereoselectivity (English)

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

stereoselectivity

1 reference

based on heuristic

inferred from title

author name string

Otton SV

1

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Gillam EM

2

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Lennard MS

3

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Tucker GT

4

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Woods HF

5

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

language of work or name

0 references

publication date

1 November 1990

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

British Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

30

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

5

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

751-760

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368177

6 June 2018

Chemical trapping of labile aldehyde intermediates in the metabolism of propranolol and oxprenolol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368177

6 June 2018

The relationship between debrisoquine oxidation phenotype and the pharmacokinetics and pharmacodynamics of propranolol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368177

6 June 2018

Characterization of a human liver cytochrome P-450 involved in the oxidation of debrisoquine and other drugs by using antibodies raised to the analogous rat enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368177

6 June 2018

N-Dealkylation of propranolol: trapping of the 3-(1-naphthoxy)-2-hydroxypropionaldehyde formed in rat liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368177

6 June 2018

Partial metabolic clearances as determinants of the oral bioavailability of propranolol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368177

6 June 2018

Food effects on propranolol systemic and oral clearance: support for a blood flow hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368177

6 June 2018

Antibodies against human cytochrome P-450db1 in autoimmune hepatitis type II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368177

6 June 2018

Use of quinidine inhibition to define the role of the sparteine/debrisoquine cytochrome P450 in metoprolol oxidation by human liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368177

6 June 2018

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368177

6 June 2018

The molecular mechanisms of two common polymorphisms of drug oxidation--evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368177

6 June 2018

Stereoselective oxidative metabolism of propranolol in the microsomal fraction from rat and human liver. Use of deuterium labeling and pseudoracemic mixtures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368177

6 June 2018

Quantitative account of propranolol metabolism in urine of normal man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368177

6 June 2018

Stereoselective hemodynamic effects of (R)-and (S)-propranolol in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368177

6 June 2018

The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368177

6 June 2018

The biological properties of the optical isomers of propranolol and their effects on cardiac arrhythmias

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1990.TB03846.X

21 January 2018

On the physiological disposition and possible mechanism of the antihypertensive action of debrisoquin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New ring-hydroxylated metabolites of propranolol: species differences and stereospecific 7-hydroxylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoselective disposition and glucuronidation of propranolol in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidation of (R)- and (S)-propranolol in human and dog liver microsomes. Species differences in stereoselectivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphic ability to metabolize propranolol alters 4-hydroxypropranolol levels but not beta blockade

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-dealkylation of propranolol in rat, dog, and man. Chemical and stereochemical aspects

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mephenytoin metabolism in vitro by human liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro inhibition studies of two isozymes of human liver cytochrome P-450. Mephenytoin p-hydroxylase and sparteine monooxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Versatile isocratic high-performance liquid chromatographic assay for propranolol and its basic, neutral and acidic metabolites in biological fluids

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irreversible binding and metabolism of propranolol by human liver microsomes--relationship to polymorphic oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved high-performance liquid chromatographic method for the simultaneous determination of propranolol and 4-hydroxypropranolol in plasma with fluorescence detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparative study of some kinetic and molecular properties of microsomal and mitochondrial monoamine oxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of hepatic cytochrome P450bufI causes genetically deficient debrisoquine oxidation in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xenobiotic and endobiotic inhibitors of cytochrome P-450dbl function, the target of the debrisoquine/sparteine type polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Propranolol's metabolism is determined by both mephenytoin and debrisoquin hydroxylase activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of debrisoquin phenotype on the inducibility of propranolol metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple pathways of propranolol's metabolism are inhibited by debrisoquin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of propranolol and six metabolites in human urine by high-pressure liquid chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/2271375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2125.1990.TB03846.X

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q41775640&oldid=1927780961"