(Q41811927)

English

Inhibition of cholesterol biosynthesis by Delta22-unsaturated phytosterols via competitive inhibition of sterol Delta24-reductase in mammalian cells

scientific article published on August 2002

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Inhibition of cholesterol biosynthesis by Delta22-unsaturated phytosterols via competitive inhibition of sterol Delta24-reductase in mammalian cells (English)

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

1 reference

ChEBI release 2020-05-28

Miguel A Lasunción

5

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

author name string

Carlos Fernández

1

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Yajaira Suárez

2

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Antonio J Ferruelo

3

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Diego Gómez-Coronado

4

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

language of work or name

0 references

publication date

1 August 2002

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Biochemical Journal

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

366

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Pt 1

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

109-119

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

A simple method for the isolation and purification of total lipides from animal tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Pharmacological properties of plant sterols in vivo and in vitro observations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Mutations in the 3beta-hydroxysterol Delta24-reductase gene cause desmosterolosis, an autosomal recessive disorder of cholesterol biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Dose-dependent effects of lovastatin on cell cycle progression. Distinct requirement of cholesterol and non-sterol mevalonate derivatives.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Genetic basis of sitosterolemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Phytosterols as anticancer dietary components: evidence and mechanism of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Plant sterol and stanol margarines and health

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

3-Hydroxy-3-methylglutaryl-coenzyme A reductase activity is inhibited by cholesterol and up-regulated by sitosterol in sitosterolemic fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Effects of dietary phytosterols on cholesterol metabolism and atherosclerosis: clinical and experimental evidence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Regulation of cholesterol metabolism by dietary plant sterols

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Regulation of rat hepatic 3beta-hydroxysterol delta7-reductase: substrate specificity, competitive and non-competitive inhibition, and phosphorylation/dephosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Cholesterol biosynthesis from lanosterol: development of a novel assay method and characterization of rat liver microsomal lanosterol delta 24-reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Comparison of intestinal absorption of cholesterol with different plant sterols in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Deficient ileal 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in sitosterolemia: sitosterol is not a feedback inhibitor of intestinal cholesterol biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Phytosterolaemia, xanthomatosis and premature atherosclerotic arterial disease: a case with high plant sterol absorption, impaired sterol elimination and low cholesterol synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Synthesis of Δ5,22-cholestadien-3β-ol from Δ5,7,22-cholestatrien-3β-ol by a liver enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Beta-sitosterolemia and xanthomatosis. A newly described lipid storage disease in two sisters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Cholesterol, phytosterol and polyunsaturated fatty acid levels in 1982 and 1957 Japanese diets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Regulation of sterol biosynthesis and of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in cultured cells by progesterone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Metabolism of 24-ethyl-4-cholesten-3-one and 24-ethyl-5-cholesten-3 beta-ol (sitosterol) after intraperitoneal injection in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

A mammalian mutant cell lacking detectable lanosterol 14 alpha-methyl demethylase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Effect of sitosterol on the rate-limiting enzymes in cholesterol synthesis and degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Inhibition of cholesterol synthesis and cell growth by 24(R,S),25-iminolanosterol and triparanol in cultured rat hepatoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

The reactivity of desmosterol and other shellfish- and xanthomatosis-associated sterols in the macrophage sterol esterification reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Sterol content of foods of plant origin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Side-chain cleavage of 4-cholesten-3-one, 5-cholesten-3α-ol, β-sitosterol, and related steroids in endocrine tissues from rat and man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

6 June 2018

Fate of intravenously administered squalene and plant sterols in human subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222779

18 August 2018

Soy sterol esters and beta-sitostanol ester as inhibitors of cholesterol absorption in human small bowel

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of plasma lipid levels and cholesterol kinetics by phytosterol versus phytostanol esters

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desmosterol as the Major Sterol in L-Cell Mouse Fibroblasts Grown in Sterol-Free Culture Medium

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of the diurnal variation of hepatic HMG-CoA reductase activity in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sterol balance studies in the rat. Effects of dietary cholesterol and β-sitosterol on sterol balance and rate-limiting enzymes of sterol metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conversion ofβ-sitosterol to steroid hormones by rat testes in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uptake and esterification of plant sterols by rat small intestine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The sterol substrate specificity of acyl CoA: :cholesterol acyltransferase from rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative lymphatic absorption of sitosterol, stigmasterol, and fucosterol and differential inhibition of cholesterol absorption

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of 3 beta-[2-(diethylamino)ethoxy]androst-5-en-17-one on the synthesis of cholesterol and ubiquinone in rat intestinal epithelial cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of BM 15.766, an inhibitor of 7-dehydrocholesterol delta 7-reductase, on cholesterol biosynthesis in primary rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cholesterol absorption in rats by plant sterols

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased sitosterol absorption, decreased removal, and expanded body pools compensate for reduced cholesterol synthesis in sitosterolemia with xanthomatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zymosterol is located in the plasma membrane of cultured human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of increased hepatic sitosterol on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and cholesterol 7 alpha-hydroxylase in the rat and sitosterolemic homozygotes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phytosterolaemia in a Norwegian family: diagnosis and characterization of the first Scandinavian case

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of micellar beta-sitosterol on cholesterol metabolism in CaCo-2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor on sterol absorption in hypercholesterolemic subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of 2 low-fat stanol ester-containing margarines on serum cholesterol concentrations as part of a low-fat diet in hypercholesterolemic subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholesterol reduction by different plant stanol mixtures and with variable fat intake

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of soybean sterols in the diet on plasma and liver cholesterol in chicks

1 reference

https://pubmed.ncbi.nlm.nih.gov/12162789

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ20011777

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

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