(Q41826580)

12 October 2017

CYP2C8 and CYP3A4 are the principal enzymes involved in the human in vitro biotransformation of the insulin secretagogue repaglinide (English)

1 reference

12 October 2017

Tanja Busk Bidstrup

1

1 reference

12 October 2017

Inga Bjørnsdottir

2

1 reference

12 October 2017

Ulla Grove Sidelmann

3

1 reference

12 October 2017

Mikael Søndergård Thomsen

4

1 reference

12 October 2017

Kristian Tage Hansen

5

1 reference

12 October 2017

language of work or name

English

0 references

publication date

1 September 2003

1 reference

British Journal of Clinical Pharmacology

12 October 2017

1 reference

12 October 2017

56

1 reference

12 October 2017

3

1 reference

12 October 2017

305-314

1 reference

The cytochrome P4503A4 inhibitor clarithromycin increases the plasma concentrations and effects of repaglinide.

12 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884358

The xenobiotic inhibitor profile of cytochrome P4502C8.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884358

Rifampin decreases the plasma concentrations and effects of repaglinide

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884358

Clinical pharmacokinetics of cerivastatin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884358

Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884358

Repaglinide: a new short-acting insulinotropic agent for the treatment of type 2 diabetes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884358

Effects of the hypoglycaemic drugs repaglinide and glibenclamide on ATP-sensitive potassium-channels and cytosolic calcium levels in beta TC3 cells and rat pancreatic beta cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884358

Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884358

Speculations on the substrate structure-activity relationship (SSAR) of cytochrome P450 enzymes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884358

Influence of drugs interacting with CYP3A4 on the pharmacokinetics, pharmacodynamics, and safety of the prandial glucose regulator repaglinide

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884358

Different contributions of cytochrome P450 2C19 and 3A4 in the oxidation of omeprazole by human liver microsomes: effects of contents of these two forms in individual human samples

18 August 2018

1 reference

12 December 2020

Absorption, metabolism and excretion of a single oral dose of (14)C-repaglinide during repaglinide multiple dosing

1 reference

12 December 2020

Affinity and potency of proinhibitory antipeptide antibodies against CYP2D6 is enhanced using cyclic peptides as immunogens

1 reference

12 December 2020

Major role of human liver microsomal cytochrome P450 2C9 (CYP2C9) in the oxidative metabolism of celecoxib, a novel cyclooxygenase-II inhibitor

1 reference

12 December 2020

Selective and potent inhibition of human CYP2C19 activity by a conformationally targeted antipeptide antibody

1 reference

12 December 2020

Structure-function analysis of human CYP3A4 using a specific proinhibitory antipeptide antibody

1 reference

12 December 2020

A significant role of human cytochrome P450 2C8 in amiodarone N-deethylation: an approach to predict the contribution with relative activity factor

1 reference

12 December 2020

Review of prandial glucose regulation with repaglinide: a solution to the problem of hypoglycaemia in the treatment of Type 2 diabetes?

1 reference

12 December 2020

Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation

1 reference

12 December 2020

Variability in human cytochrome P450 paclitaxel metabolism

1 reference

12 December 2020

Repaglinide, a novel, short-acting hypoglycemic agent for type 2 diabetes mellitus

1 reference

12 December 2020

10.1046/J.0306-5251.2003.01862.X

Identifiers

DOI

1 reference

12 October 2017

1 reference

12 October 2017

PubMed publication ID

12919179

1 reference