(Q41827851)

English

The rapid desensitization of glucagon-stimulated adenylate cyclase is a cyclic AMP-independent process that can be mimicked by hormones which stimulate inositol phospholipid metabolism

scientific article published on April 1987

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

The rapid desensitization of glucagon-stimulated adenylate cyclase is a cyclic AMP-independent process that can be mimicked by hormones which stimulate inositol phospholipid metabolism (English)

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

desensitization

1 reference

based on heuristic

inferred from title

Miles D. Houslay

5

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

author name string

G J Murphy

1

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

V J Hruby

2

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

D Trivedi

3

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

M J Wakelam

4

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

language of work or name

0 references

publication date

1 April 1987

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

number of pages

8

1 reference

based on heuristic

inferred from page(s)

Biochemical Journal

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

243

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

1

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

39-46

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Forskolin and ethanol both perturb the structure of liver plasma membranes and activate adenylate cyclase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Effect of lutropin and cycloheximide on lutropin receptors and cyclic AMP production in Leydig tumour cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Guanosine 5'-triphosphate and guanosine 5'-[beta gamma-imido]triphosphate effect a collision coupling mechanism between the glucagon receptor and catalytic unit of adenylate cyclase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Agonist-induced desensitization of the beta-adrenergic receptor-linked adenylate cyclase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Islet-activating protein blocks glucagon desensitization in intact hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

N6-(Phenylisopropyl)adenosine prevents glucagon both blocking insulin's activation of the plasma-membrane cyclic AMP phosphodiesterase and uncoupling hormonal stimulation of adenylate cyclase activity in hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Phorbol ester induces desensitization of adenylate cyclase and phosphorylation of the beta-adrenergic receptor in turkey erythrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Use of the liquid scintillation spectrometer for determining adenosine triphosphate by the luciferase enzyme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Effects of phorbol esters on alpha 1-adrenergic-mediated and glucagon-mediated actions in isolated rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Protein kinase C phosphorylates the inhibitory guanine-nucleotide-binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Pertussis toxin prevents homologous desensitization of adenylate cyclase in cultured renal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Insulin, glucagon and the receptor-mediated control of cyclic AMP concentrations in liver. Twenty-second Colworth medal lecture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Role of Ni in coupling angiotensin receptors to inhibition of adenylate cyclase in hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Adenosine potentiates lutropin-stimulated cyclic AMP production and inhibits lutropin-induced desensitization of adenylate cyclase in rat Leydig tumour cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Molecular mechanisms of receptor desensitization using the beta-adrenergic receptor-coupled adenylate cyclase system as a model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Regulation of a liver plasma membrane phosphoinositide phosphodiesterase by guanine nucleotides and calcium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

The inhibitory guanine nucleotide-binding protein (Ni) purified from bovine brain is a high affinity GTPase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Adenosine receptors and calcium: basis for proposing a third (A3) adenosine receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Modulation of cyclic AMP accumulation in GH3 cells by a phorbol ester and thyroliberin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Differential effects of tryptophan on glucose synthesis in rats and guinea pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Nalpha-trinitrophenyl glucagon: an inhibitor of glucagon-stimulated cyclic AMP production and its effects on glycogenolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

The glucagon receptor of rat liver plasma membrane can couple to adenylate cyclase without activating it.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Glycogenolytic response to glucagon of cultured fetal hepatocytes. Refractoriness following prior exposure to glucagon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

6 June 2018

Challenge of hepatocytes by glucagon triggers a rapid modulation of adenylate cyclase activity in isolated membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

18 August 2018

Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

18 August 2018

Studies on the hepatic calcium-mobilizing activity of aluminum fluoride and glucagon. Modulation by cAMP and phorbol myristate acetate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

18 August 2018

Activation of two signal-transduction systems in hepatocytes by glucagon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1147811

2 December 2018

The phorbol ester TPA inhibits cyclic AMP phosphodiesterase activity in intact hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholera toxin mediated activation of adenylate cyclase in intact rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucagon amino groups. Evaluation of modifications leading to antagonism and agonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct evidence of a glucagon-dependent regulation of the concentration of glucagon receptors in the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rat Leydig cell phospholipid content is increased by luteinizing hormone and 8-bromo-cyclic AMP

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rat liver plasma membranes contain a lipid-dependent protein kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related changes in the control of hepatic cyclic AMP levels by alpha 1- and beta 2-adrenergic receptors in male rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gonadotropin-releasing hormone stimulates phosphatidylinositol labeling and prostaglandin E production in Leydig cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between inositol polyphosphate production and the increase of cytosolic free Ca2+ induced by vasopressin in isolated hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol diesters promote β-adrenergic receptor phosphorylation and adenylate cyclase desensitization in duck erythrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic effects and cyclic AMP levels produced by glucagon, (1-N alpha-Trinitrophenylhistidine,12-homoarginine)glucagon and forskolin in isolated rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desensitization of the turkey erythrocyte beta-adrenergic receptor in a cell-free system. Evidence that multiple protein kinases can phosphorylate and desensitize the receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of adenylate cyclase activity in S49 lymphoma cells by phorbol esters. Putative effect of C kinase on alpha s-GTP-catalytic subunit interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol ester causes desensitization of gonadotropin-responsive adenylate cyclase in a murine Leydig tumor cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of hCG-stimulated adenylate cyclase in purified mouse Leydig cells by the phorbol ester PMA

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The phorbol ester TPA prevents the expression of both glucagon desensitisation and the glucagon-mediated block of insulin stimulation of the peripheral plasma membrane cyclic AMP phosphodiesterase in rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitivity of the response of cytosolic calcium in Quin-2-loaded rat hepatocytes to glucagon, adenine nucleosides, and adenine nucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of 1,2-diacylglycerol accumulation in hepatocytes by vasopressin, epinephrine, and angiotensin II

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mobilization of intracellular calcium by glucagon and cyclic AMP analogues in isolated rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3038085

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ2430039

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

ResearchGate publication ID

0 references

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