(Q41836067)

English

Site-specific anti-phosphopeptide antibodies: use in assessing insulin receptor serine/threonine phosphorylation state and identification of serine-1327 as a novel site of phorbol ester-induced phosphorylation

scientific article published on November 1994

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scholarly article

1 reference

Europe PubMed Central

12 October 2017

Site-specific anti-phosphopeptide antibodies: use in assessing insulin receptor serine/threonine phosphorylation state and identification of serine-1327 as a novel site of phorbol ester-induced phosphorylation (English)

1 reference

Europe PubMed Central

12 October 2017

phosphorylation

1 reference

based on heuristic

inferred from title

author name string

M P Coghlan

1

1 reference

Europe PubMed Central

12 October 2017

T S Pillay

2

1 reference

Europe PubMed Central

12 October 2017

J M Tavaré

3

1 reference

Europe PubMed Central

12 October 2017

K Siddle

4

1 reference

Europe PubMed Central

12 October 2017

language of work or name

0 references

publication date

1 November 1994

1 reference

Europe PubMed Central

12 October 2017

Biochemical Journal

1 reference

Europe PubMed Central

12 October 2017

303 ( Pt 3)

1 reference

Europe PubMed Central

12 October 2017

893-899

1 reference

Europe PubMed Central

12 October 2017

Pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: candidates for a signal transmitter defect causing insulin resistance of the skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Phorbol esters inhibit insulin-induced receptor down-regulation in cultured human lymphocytes: association with diminished insulin receptor autophosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Direct activation of the phosphatidylinositol 3'-kinase by the insulin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Identification of serines-967/968 in the juxtamembrane region of the insulin receptor as insulin-stimulated phosphorylation sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

The insulin receptor and its substrate: molecular determinants of early events in insulin action.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Analysis of insulin-receptor phosphorylation sites in intact cells by two-dimensional phosphopeptide mapping

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Studies on the autophosphorylation of the insulin receptor from human placenta. Analysis of the sites phosphorylated by two-dimensional peptide mapping

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Tumor-promoting phorbol esters increase the Km of the ATP-binding site of the insulin receptor kinase from rat adipocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Phosphorylation of receptors for insulin and insulin-like growth factor I. Effects of hormones and phorbol esters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Two systems in vitro that show insulin-stimulated serine kinase activity towards the insulin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Augmented mitogenesis and impaired metabolic signaling mediated by a truncated insulin receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Predominance of tyrosine phosphorylation of insulin receptors during the initial response of intact cells to insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Antibodies for phosphotyrosine: analytical and preparative tool for tyrosyl-phosphorylated proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

The rat insulin receptor: primary structure and conservation of tissue-specific alternative messenger RNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

The effect of protein kinase-C inhibition on insulin receptor phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

The insulin receptor. A multifunctional protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Threonine 1336 of the human insulin receptor is a major target for phosphorylation by protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Changes in insulin-receptor tyrosine, serine and threonine phosphorylation as a result of substitution of tyrosine-1162 with phenylalanine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

8 Generation of monoclonal antibodies against phosphotyrosine and their use for affinity purification of phosphotyrosine-containing proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

7 Preparation and use of anti-phosphotyrosine antibodies to study structure and function of insulin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Phorbol ester-mediated protein kinase C interaction with wild-type and COOH-terminal truncated insulin receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Multisite serine phosphorylation of the insulin and IGF-I receptors in transfected cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Evidence for hybrid rodent and human insulin receptors in transfected cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Intracellular signaling by a mutant human insulin receptor lacking the carboxyl-terminal tyrosine autophosphorylation sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Antiserum raised against a synthetic phosphotyrosine-containing peptide selectively recognizes p185neu/erbB-2 and the epidermal growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

A monoclonal anti-peptide antibody reacting with the insulin receptor β-subunit. Characterization of the antibody and its epitope and use in immunoaffinity purification of intact receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

6 June 2018

Phorbol esters induce insulin receptor phosphorylation in transfected fibroblasts without affecting tyrosine kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

18 August 2018

Overexpression of protein kinase C isoenzymes alpha, beta I, gamma, and epsilon in cells overexpressing the insulin receptor. Effects on receptor phosphorylation and signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

18 August 2018

Insulin-mimetic actions of phorbol ester in cultured adult rat hepatocytes. Lack of phorbol-ester-elicited inhibition of the insulin signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137630

18 August 2018

The carboxyl-terminal domain of the insulin receptor: its potential role in growth-promoting effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/7980459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[23] Production of phosphorylation state-specific antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/7980459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solid-phase synthesis of a range of O-phosphorylated peptides by post-assembly phosphitylation and oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7980459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced insulin-induced mitogenesis and mitogen-activated protein kinase activities in mutant insulin receptors with substitution of two COOH-terminal tyrosine autophosphorylation sites by phenylalanine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7980459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The insulin receptor activation process involves localized conformational changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7980459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preparation of anti-phosphoserine and anti-phosphothreonine antibodies and their application in the study of insulin- and EGF-induced phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7980459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human insulin receptor mutated at threonine 1336 functions normally in Chinese hamster ovary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7980459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The insulin receptor C-terminus is involved in regulation of the receptor kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7980459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of insulin receptor tyrosine residues autophosphorylated in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/7980459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol ester-induced serine phosphorylation of the insulin receptor decreases its tyrosine kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7980459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibodies directed against phosphothreonine residues as potent tools for studying protein phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7980459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibodies and radioimmunoassays for phosphoserine, phosphothreonine and phosphotyrosine. Serologic specificities and levels of the phosphoamino acids in cytoplasmic fractions of rat tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/7980459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-sensitive phosphorylation of serine 1293/1294 on the human insulin receptor by a tightly associated serine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/7980459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin binding to its receptor induces a conformational change in the receptor C-terminus

1 reference

https://pubmed.ncbi.nlm.nih.gov/7980459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3030893

1 reference

Europe PubMed Central

12 October 2017

1 reference

Europe PubMed Central

12 October 2017

1 reference

Europe PubMed Central

12 October 2017

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0 references

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