(Q41838448)

13 October 2017

Activated alveolar epithelial cells initiate fibrosis through secretion of mesenchymal proteins (English)

1 reference

13 October 2017

Jibing Yang

1

1 reference

13 October 2017

Sarah E Wheeler

2

1 reference

13 October 2017

Miranda Velikoff

3

1 reference

13 October 2017

Kathryn R Kleaveland

4

1 reference

13 October 2017

Michael J LaFemina

5

1 reference

13 October 2017

James A Frank

6

1 reference

13 October 2017

Harold A Chapman

7

1 reference

13 October 2017

Paul J Christensen

8

1 reference

13 October 2017

Kevin K Kim

9

1 reference

13 October 2017

language of work or name

English

0 references

publication date

5 September 2013

1 reference

The American Journal of Pathology

13 October 2017

1 reference

13 October 2017

183

1 reference

13 October 2017

5

1 reference

13 October 2017

1559-1570

1 reference

describes a project that uses

13 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3814683/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Bleomycin induces molecular changes directly relevant to idiopathic pulmonary fibrosis: a model for "active" disease

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CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis

6 June 2018

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Epithelial-mesenchymal transition in the pathophysiology of airway remodelling in asthma

6 June 2018

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Pulmonary fibrosis induced by γ-herpesvirus in aged mice is associated with increased fibroblast responsiveness to transforming growth factor-β.

6 June 2018

1 reference

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Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

6 June 2018

1 reference

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Polymerized-type I collagen induces upregulation of Foxp3-expressing CD4 regulatory T cells and downregulation of IL-17-producing CD4⁺ T cells (Th17) cells in collagen-induced arthritis.

6 June 2018

1 reference

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Ligand-independent transforming growth factor-β type I receptor signalling mediates type I collagen-induced epithelial-mesenchymal transition

6 June 2018

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Integrating mechanisms of pulmonary fibrosis

6 June 2018

1 reference

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Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in mice

6 June 2018

1 reference

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Alveolar epithelial cells express mesenchymal proteins in patients with idiopathic pulmonary fibrosis

6 June 2018

1 reference

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Hepatocyte-derived Snail1 propagates liver fibrosis progression

6 June 2018

1 reference

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Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis

6 June 2018

1 reference

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Thrombospondin-1-deficient mice are not protected from bleomycin-induced pulmonary fibrosis

6 June 2018

1 reference

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The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in humans and mice

6 June 2018

1 reference

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Surfactant protein A2 mutations associated with pulmonary fibrosis lead to protein instability and endoplasmic reticulum stress.

6 June 2018

1 reference

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Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Endothelial-mesenchymal transition in bleomycin-induced pulmonary fibrosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Integrin alpha3beta1-dependent beta-catenin phosphorylation links epithelial Smad signaling to cell contacts

6 June 2018

1 reference

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Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

A noncytotoxic DsRed variant for whole-cell labeling

6 June 2018

1 reference

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Pneumocystis murina infection and cigarette smoke exposure interact to cause increased organism burden, development of airspace enlargement, and pulmonary inflammation in mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis?

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Molecular targets in pulmonary fibrosis: the myofibroblast in focus.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

The myofibroblast: one function, multiple origins

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Mammalian collagen receptors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Role of epithelial cells in idiopathic pulmonary fibrosis: from innocent targets to serial killers

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Cell-specific gene expression in patients with usual interstitial pneumonia

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Expression of HSP47 in usual interstitial pneumonia and nonspecific interstitial pneumonia

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT)

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Mechanisms of pulmonary fibrosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Bone marrow-derived progenitor cells in pulmonary fibrosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Epithelial-mesenchymal transition and its implications for fibrosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

The role of connective tissue growth factor, a multifunctional matricellular protein, in fibroblast biology

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Distinct ligand binding sites in integrin α3β1 regulate matrix adhesion and cell–cell contact

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Evidence that fibroblasts derive from epithelium during tissue fibrosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

A mutation in the surfactant protein C gene associated with familial interstitial lung disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

A potent far-upstream enhancer in the mouse pro alpha 2(I) collagen gene regulates expression of reporter genes in transgenic mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Identification of a minimal sequence of the mouse pro-alpha 1(I) collagen promoter that confers high-level osteoblast expression in transgenic mice and that binds a protein selectively present in osteoblasts

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Noncovalenly PEGylated CTGF siRNA/PDMAEMA complex for pulmonary treatment of bleomycin-induced lung fibrosis

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Physical and chemical microenvironmental cues orthogonally control the degree and duration of fibrosis-associated epithelial-to-mesenchymal transitions.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Connective tissue growth factor promoter activity in normal and wounded skin

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Expression of Col1a1, Col1a2 and procollagen I in germ cells of immature and adult mouse testis.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814683

Pulmonary microvascular endothelial cells from bleomycin-induced rats promote the transformation and collagen synthesis of fibroblasts

18 August 2018

1 reference

12 December 2020

American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS)

1 reference

12 December 2020

Involvement of collagen-binding heat shock protein 47 and procollagen type I synthesis in idiopathic pulmonary fibrosis: contribution of type II pneumocytes to fibrosis

1 reference

12 December 2020

An essential role for resident fibroblasts in experimental lung fibrosis is defined by lineage-specific deletion of high-affinity type II transforming growth factor β receptor

1 reference

12 December 2020

Procollagen types I and III aminoterminal propeptide levels during acute respiratory distress syndrome and in response to methylprednisolone treatment

1 reference

12 December 2020

Type II alveolar epithelial cells and interstitial fibroblasts express connective tissue growth factor in IPF

1 reference

12 December 2020

Subcutaneous administration of polymerized type I collagen downregulates interleukin (IL)-17A, IL-22 and transforming growth factor-β1 expression, and increases Foxp3-expressing cells in localized scleroderma

1 reference

12 December 2020

Resolved: EMT produces fibroblasts in the kidney

1 reference

12 December 2020

Transforming growth factor-beta1 regulates basement membrane formation by alveolar epithelial cells in vitro

1 reference

12 December 2020

Isolation and primary culture of murine alveolar type II cells

1 reference

12 December 2020

Propeptide levels of type III and type I procollagen in the serum and bronchoalveolar lavage fluid of patients with pulmonary sarcoidosis

1 reference

12 December 2020

Collagen production by human mesothelial cells in vitro

1 reference

12 December 2020

Type III and type I procollagen markers in fibrosing alveolitis

1 reference

12 December 2020

10.1016/J.AJPATH.2013.07.016

Identifiers

DOI

1 reference

13 October 2017

1 reference

13 October 2017

PubMed publication ID

24012677

1 reference