(Q41844898)

13 October 2017

A small molecular scaffold for selective inhibition of Wip1 phosphatase (English)

1 reference

13 October 2017

Jeong Bang

1

1 reference

13 October 2017

Stewart R Durell

3

1 reference

13 October 2017

Ettore Appella

4

1 reference

13 October 2017

Daniel H Appella

5

1 reference

13 October 2017

Hiroshi Yamaguchi

2

1 reference

13 October 2017

1 February 2008

1 reference

13 October 2017

1 reference

13 October 2017

3

1 reference

13 October 2017

2

1 reference

13 October 2017

230-232

1 reference

All-atom empirical potential for molecular modeling and dynamics studies of proteins

13 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824627

Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824627

Intrinsic kinase activity and SQ/TQ domain of Chk2 kinase as well as N-terminal domain of Wip1 phosphatase are required for regulation of Chk2 by Wip1.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824627

Chemical inhibition of Wip1 phosphatase contributes to suppression of tumorigenesis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824627

Substrate specificity of the human protein phosphatase 2Cdelta, Wip1

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824627

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824627

Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824627

p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824627

Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824627

Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824627

Crystal structure of the protein serine/threonine phosphatase 2C at 2.0 A resolution

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824627

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824627

Synthesis and biological activity of new HMG-CoA reductase inhibitors. 2. Derivatives of 7-(1H-pyrrol-3-yl)-substituted-3,5-dihydroxyhept-6(E)-enoic (-heptanoic) acids

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824627

The Wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by PI3K-like kinases

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824627

The role of the MKK6/p38 MAPK pathway in Wip1-dependent regulation of ErbB2-driven mammary gland tumorigenesis.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824627

The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18022979

12 December 2020

inferred from PubMed ID database lookup

Development of a substrate-based cyclic phosphopeptide inhibitor of protein phosphatase 2Cdelta, Wip1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18022979

12 December 2020

inferred from PubMed ID database lookup

Transcription factors control invasion: AP-1 the first among equals

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FCMDC.200700281

7 January 2021

inferred from DOI database lookup

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FCMDC.200700281

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1002/CMDC.200700281

1 reference

13 October 2017

1 reference

13 October 2017

PubMed publication ID

18022979

1 reference