(Q41845464)

English

Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft.

scientific article published on July 2004

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15084146%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft (English)

1 reference

Europe PubMed Central

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27 December 2019

3

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27 December 2019

4

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27 December 2019

author name string

Igor Stern

1

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27 December 2019

Norbert Schaschke

2

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27 December 2019

language of work or name

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publication date

1 July 2004

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27 December 2019

Biochemical Journal

1 reference

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27 December 2019

381

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27 December 2019

Pt 2

1 reference

Europe PubMed Central

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27 December 2019

511-517

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15084146%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Raster3D: photorealistic molecular graphics

1 reference

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6 June 2018

Cathepsin B and its role(s) in cancer progression

1 reference

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6 June 2018

Cell-surface cathepsin B: Understanding its functional significance

1 reference

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6 June 2018

Apoptotic pathways: involvement of lysosomal proteases

1 reference

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6 June 2018

Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Epoxysuccinyl peptide-derived affinity labels for cathepsin B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Lysosomal cysteine proteases: more than scavengers

1 reference

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6 June 2018

Unraveling the role of proteases in cancer

1 reference

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6 June 2018

Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Inhibition mechanism of cathepsin L-specific inhibitors based on the crystal structure of papain-CLIK148 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Rapid automated molecular replacement by evolutionary search

1 reference

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6 June 2018

The crystal structure of human procathepsin K

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Design of potent and selective human cathepsin K inhibitors that span the active site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Crystal structure of human osteoclast cathepsin K complex with E-64

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Crystal structures of human procathepsin B at 3.2 and 3.3 Angstroms resolution reveal an interaction motif between a papain-like cysteine protease and its propeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

How to measure and predict the molar absorption coefficient of a protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Cathepsin B, Cathepsin H, and cathepsin L

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

On the size of the active site in proteases. I. Papain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Crystal structure of a papain-E-64 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Refined x-ray structure of papain.E-64-c complex at 2.1-A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Crystal structure of an actinidin-E-64 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Crystal structure of papain-E64-c complex. Binding diversity of E64-c to papain S2 and S3 subsites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

6 June 2018

Cathepsin B in osteoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

18 August 2018

Presence of cathepsin B in the human pancreatic secretory pathway and its role in trypsinogen activation during hereditary pancreatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133859

18 August 2018

Significance of cathepsin B accumulation in synovial fluid of rheumatoid arthritis

1 reference

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18 August 2018

Stimulation of angiogenesis through cathepsin B inactivation of the tissue inhibitors of matrix metalloproteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15084146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15084146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-cyclodextrin/epoxysuccinyl peptide conjugates: a new drug targeting system for tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15084146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relative importance of cysteine peptidases in osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15084146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of mature cathepsin B in aging rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/15084146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystallization and preliminary X-ray study of the cathepsin B complexed with CA074, a selective inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15084146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel epoxysuccinyl peptides. Selective inhibitors of cathepsin B, in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/15084146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel epoxysuccinyl peptides. A selective inhibitor of cathepsin B, in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15084146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://pubmed.ncbi.nlm.nih.gov/15084146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bovine stefin C, a new member of the stefin family

1 reference

https://pubmed.ncbi.nlm.nih.gov/15084146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding mode of CA074, a specific irreversible inhibitor, to bovine cathepsin B as determined by X-ray crystal analysis of the complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/15084146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E-64 analogues as inhibitors of cathepsin B. On the role of the absolute configuration of the epoxysuccinyl group

1 reference

https://pubmed.ncbi.nlm.nih.gov/15084146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate/propeptide-derived endo-epoxysuccinyl peptides as highly potent and selective cathepsin B inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15084146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ20040237

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15084146%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15084146%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15084146%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

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