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English
Targeting SRC and epidermal growth factor receptor in colorectal cancer: rationale and progress into the clinic.
scientific article published on January 2007
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2666842
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
title
Targeting SRC and epidermal growth factor receptor in colorectal cancer: rationale and progress into the clinic
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2666842
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
main subject
colorectal cancer
1 reference
based on heuristic
inferred from title
author name string
Scott Kopetz
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2666842
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
publication date
1 January 2007
1 reference
stated in
Europe PubMed Central
PMC publication ID
2666842
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
published in
Gastrointestinal cancer research : GCR
1 reference
stated in
Europe PubMed Central
PMC publication ID
2666842
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
volume
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2666842
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
issue
4 Suppl 2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2666842
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
page(s)
S37-41
1 reference
stated in
Europe PubMed Central
PMC publication ID
2666842
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
cites work
Clinical development of SRC tyrosine kinase inhibitors in lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
A historical perspective of the EGF receptor and related systems.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
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6 June 2018
Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
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6 June 2018
Treatment for advanced tumors: SRC reclaims center stage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
c-Src regulates constitutive and EGF-mediated VEGF expression in pancreatic tumor cells through activation of phosphatidyl inositol-3 kinase and p38 MAPK.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Expression and activity of SRC regulate interleukin-8 expression in pancreatic adenocarcinoma cells: implications for angiogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Epidermal growth factor receptor (EGFR)-related protein inhibits multiple members of the EGFR family in colon and breast cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
SRC gene expression in human cancer: the role of transcriptional activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Src family kinases in tumor progression and metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Src promotes destruction of c-Cbl: implications for oncogenic synergy between Src and growth factor receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
STAT5b, a Mediator of Synergism between c-Src and the Epidermal Growth Factor Receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Activation of Src kinase in primary colorectal carcinoma: an indicator of poor clinical prognosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
pp60(cSrc) is a caspase-3 substrate and Is essential for the transformed phenotype of A431 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Employment of the epidermal growth factor receptor in growth factor-independent signaling pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Stat3 activation is required for cellular transformation by v-src
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
c-Src is required for stimulation of gelsolin-associated phosphatidylinositol 3-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Down-regulation of vascular endothelial growth factor in a human colon carcinoma cell line transfected with an antisense expression vector specific for c-src
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
A role for epidermal growth factor receptor, c-Src and focal adhesion kinase in an in vitro model for the progression of colon cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Epidermal‐Growth‐Factor‐Dependent Activation of the Src‐Family Kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Activation of pp60c-src protein kinase activity in human colon carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
6 June 2018
Src family kinase members have a common response to histone deacetylase inhibitors in human colon cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
18 August 2018
Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
18 August 2018
Somatic mutations of EGFR in colorectal cancers and glioblastomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842
retrieved
18 August 2018
Down-regulation of the tumor suppressor gene C-terminal Src kinase: an early event during premalignant colonic epithelial hyperproliferation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19360146
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Site-specific differences in pp60c-src activity in human colorectal metastases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19360146
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
PMC publication ID
2666842
1 reference
stated in
Europe PubMed Central
PMC publication ID
2666842
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
PubMed publication ID
19360146
1 reference
stated in
Europe PubMed Central
PMC publication ID
2666842
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
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