(Q41847044)

English

Defining the molecular forces that determine the impact of neomycin on bacterial protein synthesis: importance of the 2'-amino functionality

scientific article published on 12 March 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Defining the molecular forces that determine the impact of neomycin on bacterial protein synthesis: importance of the 2'-amino functionality (English)

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Daniel S. Pilch

7

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

author name string

Christopher M Barbieri

1

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Malvika Kaul

2

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Melanie Bozza-Hingos

3

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Fang Zhao

4

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Yitzhak Tor

5

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Thomas Hermann

6

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

language of work or name

0 references

publication date

12 March 2007

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

51

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

5

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

1760-1769

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

A simple NMR analysis of the protonation equilibrium that accompanies aminoglycoside recognition: dramatic alterations in the neomycin-B protonation state upon binding to a 23-mer RNA aptamer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Aminoglycoside-induced reduction in nucleotide mobility at the ribosomal RNA A-site as a potentially key determinant of antibacterial activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Exploring the use of conformationally locked aminoglycosides as a new strategy to overcome bacterial resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Complete thermodynamic characterization of the multiple protonation equilibria of the aminoglycoside antibiotic paromomycin: a calorimetric and natural abundance 15N NMR study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Conformational constraint as a means for understanding RNA-aminoglycoside specificity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Defining the basis for the specificity of aminoglycoside-rRNA recognition: a comparative study of drug binding to the A sites of Escherichia coli and human rRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Deciphering the origins of observed heat capacity changes for aminoglycoside binding to prokaryotic and eukaryotic ribosomal RNA a-sites: a calorimetric, computational, and osmotic stress study.

1 reference

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5 June 2018

Thermodynamics of aminoglycoside-rRNA recognition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Coupling of drug protonation to the specific binding of aminoglycosides to the A site of 16 S rRNA: elucidation of the number of drug amino groups involved and their identities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Crystal structure of geneticin bound to a bacterial 16S ribosomal RNA A site oligonucleotide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Crystal structure of a complex between the aminoglycoside tobramycin and an oligonucleotide containing the ribosomal decoding a site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Thermodynamics of aminoglycoside-rRNA recognition: the binding of neomycin-class aminoglycosides to the A site of 16S rRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Crystal structure of paromomycin docked into the eubacterial ribosomal decoding A site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Determination of minimum inhibitory concentrations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Recognition of cognate transfer RNA by the 30S ribosomal subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Recognition of the codon-anticodon helix by ribosomal RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Structural origins of gentamicin antibiotic action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Paromomycin binding induces a local conformational change in the A-site of 16 S rRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

RNA sequence determinants for aminoglycoside binding to an A-site rRNA model oligonucleotide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Evaluation of linked protonation effects in protein binding reactions using isothermal titration calorimetry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

An antibiotic-binding motif of an RNA fragment derived from the A-site-related region of Escherichia coli 16S rRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Interaction of antibiotics with functional sites in 16S ribosomal RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Mutations in 16S ribosomal RNA disrupt antibiotic--RNA interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Dynamics of mismatched base pairs in DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Interaction of antibiotics with A- and P-site-specific bases in 16S ribosomal RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

5 June 2018

Nonspecific interaction of lac repressor with DNA: an association reaction driven by counterion release.

1 reference

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The molecular theory of polyelectrolyte solutions with applications to the electrostatic properties of polynucleotides

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5 June 2018

Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity

1 reference

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5 June 2018

Molecular recognition of RNA by neomycin and a restricted neomycin derivative.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855527

18 August 2018

A simple structural-based approach to prevent aminoglycoside inactivation by bacterial defense proteins. Conformational restriction provides effective protection against neomycin-B nucleotidylation by ANT4.

1 reference

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18 August 2018

Monitoring molecular recognition of the ribosomal decoding site

1 reference

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18 August 2018

Aminoglycoside complexation with a DNA.RNA hybrid duplex: the thermodynamics of recognition and inhibition of RNA processing enzymes.

1 reference

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RNA polymerase alters the mobility of an A-residue crucial to polymerase-induced melting of promoter DNA.

1 reference

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18 August 2018

Specificity of aminoglycoside antibiotics for the A-site of the decoding region of ribosomal RNA

1 reference

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Enthalpy and heat capacity changes for the proton dissociation of various buffer components in 0.1 M potassium chloride

1 reference

https://pubmed.ncbi.nlm.nih.gov/17353247

12 December 2020

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Structure and dynamics of a fluorescent DNA oligomer containing the EcoRI recognition sequence: fluorescence, molecular dynamics, and NMR studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/17353247

12 December 2020

based on heuristic

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Dissociation rate of cognate peptidyl-tRNA from the A-site of hyper-accurate and error-prone ribosomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17353247

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based on heuristic

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Tight binding affinities determined from thermodynamic linkage to protons by titration calorimetry

1 reference

https://pubmed.ncbi.nlm.nih.gov/17353247

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based on heuristic

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Large contributions of coupled protonation equilibria to the observed enthalpy and heat capacity changes for ssDNA binding to Escherichia coli SSB protein

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.01267-06

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

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