(Q41847287)

13 October 2017

A novel inhibitor of human La protein with anti-HBV activity discovered by structure-based virtual screening and in vitro evaluation (English)

1 reference

13 October 2017

1 reference

Jing Tang

1

1 reference

13 October 2017

Zhi-Min Huang

2

1 reference

13 October 2017

Ying-Yi Chen

3

1 reference

13 October 2017

Zhao-Hui Zhang

4

1 reference

13 October 2017

Gao-Lin Liu

5

1 reference

13 October 2017

Jian Zhang

6

1 reference

13 October 2017

language of work or name

English

0 references

publication date

27 April 2012

1 reference

13 October 2017

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13 October 2017

7

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13 October 2017

4

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13 October 2017

e36363

1 reference

Creative Commons Attribution 4.0 International

13 October 2017

start time

27 April 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Ligand and structure based virtual screening strategies for hit-finding and optimization of hepatitis C virus (HCV) inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

Structure-based virtual screening, synthesis and SAR of novel inhibitors of hepatitis C virus NS5B polymerase.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

Structure-based discovery of triphenylmethane derivatives as inhibitors of hepatitis C virus helicase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

Drug targets in hepatitis B virus infection.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3′ Ends by the Human La Protein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

C-terminal processing of yeast Spt7 occurs in the absence of functional SAGA complex

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

Structural basis for recognition and sequestration of UUU(OH) 3' temini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

Functional characterization of the interaction between human La and hepatitis B virus RNA.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

Inhibition of human La protein by RNA interference downregulates hepatitis B virus mRNA in 2.2.15 cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

Molecular characterization of the human La protein.hepatitis B virus RNA.B interaction in vitro.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

Characterization of nuclear RNases that cleave hepatitis B virus RNA near the La protein binding site

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

Recognition of nascent RNA by the human La antigen: conserved and divergent features of structure and function

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

Binding of the La autoantigen to the hepatitis C virus 3' untranslated region protects the RNA from rapid degradation in vitro

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

La autoantigen specifically recognizes a predicted stem-loop in hepatitis B virus RNA

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

The hepatitis B virus posttranscriptional regulatory element is composed of two subelements

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

Production of hepatitis B virus particles in Hep G2 cells transfected with cloned hepatitis B virus DNA.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

A stimulatory role for the La-related protein 4B in translation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

Discovery of novel HCV polymerase inhibitors using pharmacophore-based virtual screening

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

A tetrazolium-based colorimetric MTT assay to quantitate human monocyte mediated cytotoxicity against leukemic cells from cell lines and patients with acute myeloid leukemia.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338670

Hepatitis B virus infection

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22558448

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

[A study on the relativity between La protein and the stability of HBV mRNA and the expression of HBV protein]

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22558448

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0036363

1 reference

13 October 2017

0 references

1 reference

13 October 2017

PubMed publication ID

22558448

1 reference