(Q41847449)

13 October 2017

Identification of an astrocyte cell population from human brain that expresses perforin, a cytotoxic protein implicated in immune defense (English)

1 reference

13 October 2017

0 references

P Gasque

1

1 reference

13 October 2017

J Jones

series ordinal

2

1 reference

13 October 2017

S K Singhrao

series ordinal

3

1 reference

13 October 2017

B Morgan

series ordinal

4

1 reference

13 October 2017

language of work or name

English

0 references

publication date

1 February 1998

1 reference

Journal of Experimental Medicine

13 October 2017

1 reference

13 October 2017

187

1 reference

13 October 2017

4

1 reference

13 October 2017

451-460

1 reference

The Norton Lecture: a review of the oligodendrocyte in the multiple sclerosis lesion

13 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in the brain?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Multiple sclerosis: Fas signaling in oligodendrocyte cell death

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Decreased tumor surveillance in perforin-deficient mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Expression of complement in the brain: role in health and disease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Cytotoxic T cells: more weapons for new targets?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

The central nervous system as an immunocompetent organ: role of glial cells in antigen presentation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Expression and characterization of functionally active recombinant perforin produced in insect cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Expression of the complement classical pathway by human glioma in culture. A model for complement expression by nerve cells.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Loss of cytotoxic T lymphocyte function in Chediak-Higashi syndrome arises from a secretory defect that prevents lytic granule exocytosis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Perforin: structure and function

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Molecular cloning and chromosomal assignment of a human perforin (PFP) gene

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Subcellular localization of perforin and serine esterase in lymphokine-activated killer cells and cytotoxic T cells by immunogold labeling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

A central role of perforin in cytolysis?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Imaging Ca2+ changes in individual oligodendrocytes attacked by T-cell perforin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Occurrence of oligodendrocytes within astrocytes in demyelinating lesions

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

T-cell recognition of myelin basic protein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Immunohistochemical identification of cytotoxic lymphocytes using human perforin monoclonal antibody

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

SP-40,40 immunoreactivity in inflammatory CNS lesions displaying astrocyte/oligodendrocyte interactions.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212151

Cytotoxic T cells: more weapons for new targets?

18 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.187.4.451

Identification and characterization of the complement C5a anaphylatoxin receptor on human astrocytes

21 January 2018

1 reference

12 December 2020

Role of complement in the aetiology of Pick's disease?

1 reference

12 December 2020

Expression and function of membrane regulators of complement on rat astrocytes in culture

1 reference

12 December 2020

Neurons induced to express major histocompatibility complex class I antigen are killed via the perforin and not the Fas (APO-1/CD95) pathway

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.187.4.451

1 reference

13 October 2017

1 reference

13 October 2017

PubMed publication ID

9463395

1 reference