(Q41880176)

English

The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii.

scientific article published on 22 June 2012

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6 February 2020

The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii (English)

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6 February 2020

Toxoplasma gondii

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inferred from title

12

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6 February 2020

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6 February 2020

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Elisabeth Kravets

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6 February 2020

Daniel Degrandi

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6 February 2020

Stefanie Weidtkamp-Peters

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6 February 2020

Britta Ries

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6 February 2020

Carolin Konermann

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6 February 2020

Suren Felekyan

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6 February 2020

Julia M Dargazanli

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Gerrit J K Praefcke

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6 February 2020

Lutz Schmitt

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6 February 2020

Sander H J Smits

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22 June 2012

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6 February 2020

Journal of Biological Chemistry

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6 February 2020

287

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6 February 2020

33

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6 February 2020

27452-27466

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6 February 2020

GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals

1 reference

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5 June 2018

The guanine cap of human guanylate-binding protein 1 is responsible for dimerization and self-activation of GTP hydrolysis

1 reference

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5 June 2018

Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it

1 reference

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5 June 2018

A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection

1 reference

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5 June 2018

Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes

1 reference

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5 June 2018

The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii

1 reference

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5 June 2018

Structural basis for the nucleotide-dependent dimerization of the large G protein atlastin-1/SPG3A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

The guanylate-binding proteins: emerging insights into the biochemical properties and functions of this family of large interferon-induced guanosine triphosphatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

The immunity-related GTPases in mammals: a fast-evolving cell-autonomous resistance system against intracellular pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Role of GTP Binding, Isoprenylation, and the C-Terminal α-Helices in the Inhibition of Cell Spreading by the Interferon-Induced GTPase, Mouse Guanylate-Binding Protein-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Dynamin-like MxA GTPase: structural insights into oligomerization and implications for antiviral activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Purification of the CaaX-modified, dynamin-related large GTPase hGBP1 by coexpression with farnesyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Allosteric modulation of Ras positions Q61 for a direct role in catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Biochemical properties of the human guanylate binding protein 5 and a tumor-specific truncated splice variant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Localisation and mislocalisation of the interferon-inducible immunity-related GTPase, Irgm1 (LRG-47) in mouse cells

1 reference

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5 June 2018

Human guanylate binding proteins potentiate the anti-chlamydia effects of interferon-gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Toxoplasma gondii and the Immunity-Related GTPase (IRG) resistance system in mice: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Multiparameter fluorescence image spectroscopy to study molecular interactions

1 reference

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5 June 2018

Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Analyses of murine GBP homology clusters based on in silico, in vitro and in vivo studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Induction of guanylate binding protein 5 by gamma interferon increases susceptibility to Salmonella enterica serovar Typhimurium-induced pyroptosis in RAW 264.7 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Emerging themes in IFN-gamma-induced macrophage immunity by the p47 and p65 GTPase families.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Monitoring dynamic systems with multiparameter fluorescence imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

The interferon-inducible GTPases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Nucleotide binding and self-stimulated GTPase activity of human guanylate-binding protein 1 (hGBP1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

The guanylate-binding proteins (GBPs): proinflammatory cytokine-induced members of the dynamin superfamily with unique GTPase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

GBP1 overexpression is associated with a paclitaxel resistance phenotype

1 reference

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5 June 2018

Golgi targeting of human guanylate-binding protein-1 requires nucleotide binding, isoprenylation, and an IFN-gamma-inducible cofactor

1 reference

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5 June 2018

p47 GTPases regulate Toxoplasma gondii survival in activated macrophages

1 reference

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5 June 2018

The Ras superfamily at a glance

1 reference

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5 June 2018

Immune control of phagosomal bacteria by p47 GTPases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Identification of residues in the human guanylate-binding protein 1 critical for nucleotide binding and cooperative GTP hydrolysis

1 reference

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5 June 2018

IFN-inducible GTPases and immunity to intracellular pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Dynamin GTPase domain mutants that differentially affect GTP binding, GTP hydrolysis, and clathrin-mediated endocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

p47 GTPases: regulators of immunity to intracellular pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

The dynamin superfamily: universal membrane tubulation and fission molecules?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

An assembly-incompetent mutant establishes a requirement for dynamin self-assembly in clathrin-mediated endocytosis in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47

1 reference

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5 June 2018

Role of cytokines and major histocompatibility complex restriction in mouse resistance to infection with a natural recombinant strain (type I-III) of Toxoplasma gondii

1 reference

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Cellular Localization, Oligomerization, and Membrane Association of the Hereditary Spastic Paraplegia 3A (SPG3A) Protein Atlastin

1 reference

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5 June 2018

Imaging molecular interactions in cells by dynamic and static fluorescence anisotropy (rFLIM and emFRET).

1 reference

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5 June 2018

The guanylate binding protein-1 GTPase controls the invasive and angiogenic capability of endothelial cells through inhibition of MMP-1 expression

1 reference

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5 June 2018

IIGP1, an Interferon-γ-inducible 47-kDa GTPase of the Mouse, Showing Cooperative Enzymatic Activity and GTP-dependent Multimerization

1 reference

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Interferon-induced mx proteins: dynamin-like GTPases with antiviral activity

1 reference

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5 June 2018

The guanine nucleotide-binding switch in three dimensions

1 reference

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5 June 2018

Dynamin GTPase domain mutants block endocytic vesicle formation at morphologically distinct stages

1 reference

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5 June 2018

Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection

1 reference

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5 June 2018

GTPase activity of dynamin and resulting conformation change are essential for endocytosis

1 reference

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5 June 2018

Different subcellular localizations for the related interferon-induced GTPases, MuGBP-1 and MuGBP-2: implications for different functions?

1 reference

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5 June 2018

Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism

1 reference

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5 June 2018

Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins

1 reference

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5 June 2018

Nucleotide-binding characteristics of human guanylate-binding protein 1 (hGBP1) and identification of the third GTP-binding motif

1 reference

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5 June 2018

Interferon-induced guanylate binding protein-1 (GBP-1) mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus

1 reference

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5 June 2018

Two families of GTPases dominate the complex cellular response to IFN-gamma

1 reference

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5 June 2018

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

1 reference

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5 June 2018

Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras

1 reference

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5 June 2018

Cellular responses to interferon-gamma

1 reference

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5 June 2018

Ras and its effectors

1 reference

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5 June 2018

The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding

1 reference

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5 June 2018

Dominant-negative mutants of human MxA protein: domains in the carboxy-terminal moiety are important for oligomerization and antiviral activity

1 reference

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5 June 2018

Dynamin self-assembly stimulates its GTPase activity

1 reference

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5 June 2018

GTPase properties of the interferon-induced human guanylate-binding protein 2

1 reference

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5 June 2018

A functional GTP-binding motif is necessary for antiviral activity of Mx proteins

1 reference

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5 June 2018

Effects of mutant rat dynamin on endocytosis

1 reference

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5 June 2018

Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

1 reference

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5 June 2018

The interferon-induced 67-kDa guanylate-binding protein (hGBP1) is a GTPase that converts GTP to GMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Mutant ras-encoded proteins with altered nucleotide binding exert dominant biological effects

1 reference

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5 June 2018

Transphosphorylation and G protein activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

The GTPase superfamily: conserved structure and molecular mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Interferon-induced human protein MxA is a GTPase which binds transiently to cellular proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

5 June 2018

Mechanism of GTPase-activity-induced self-assembly of human guanylate binding protein 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

18 August 2018

Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

18 August 2018

Nucleotide dependent cysteine reactivity of hGBP1 uncovers a domain movement during GTP hydrolysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

18 August 2018

Transient kinetic investigation of GTP hydrolysis catalyzed by interferon-gamma-induced hGBP1 (human guanylate binding protein 1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

18 August 2018

New insights into the role of conserved, essential residues in the GTP binding/GTP hydrolytic cycle of large G proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

18 August 2018

Inhibition of VSV and EMCV replication by the interferon-induced GTPase, mGBP-2: differential requirement for wild-type GTP binding domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431654

18 August 2018

In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters

1 reference

https://pubmed.ncbi.nlm.nih.gov/22730319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluoroaluminates activate transducin-GDP by mimicking the gamma-phosphate of GTP in its binding site

1 reference

https://pubmed.ncbi.nlm.nih.gov/22730319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-molecule detection and identification of multiple species by multiparameter fluorescence detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/22730319

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.379636

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22730319%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22730319%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22730319%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

ResearchGate publication ID

0 references

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