(Q41895997)

English

The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic.

scientific article published on March 1998

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9494119%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9494119%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Matthias P Wymann

5

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9 November 2019

author name string

R M Tombes

1

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9 November 2019

K L Auer

2

1 reference

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9 November 2019

R Mikkelsen

3

1 reference

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9 November 2019

K Valerie

4

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9 November 2019

C J Marshall

6

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9 November 2019

M McMahon

7

1 reference

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9 November 2019

P Dent

8

1 reference

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9 November 2019

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publication date

1 March 1998

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9 November 2019

number of pages

10

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Biochemical Journal

1 reference

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9 November 2019

330 ( Pt 3)

1 reference

Europe PubMed Central

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9 November 2019

1451-1460

1 reference

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9494119%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Differential regulation of the mitogen-activated protein and stress-activated protein kinase cascades by adrenergic agonists in quiescent and regenerating adult rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase

1 reference

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5 June 2018

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Protein kinase C isozyme-mediated cell cycle arrest involves induction of p21(waf1/cip1) and p27(kip1) and hypophosphorylation of the retinoblastoma protein in intestinal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Liver regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Activation of the human androgen receptor through a protein kinase A signaling pathway

1 reference

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5 June 2018

Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Liver regeneration 3: Regulation of signal transduction during liver regeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

The role of MAP kinase kinase in interleukin-3 stimulation of proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Induction of apoptosis by the low-affinity NGF receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Distinct roles for cyclin-dependent kinases in cell cycle control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Hepatic gene therapy: efficient gene delivery and expression in primary hepatocytes utilizing a conjugated adenovirus-DNA complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Quantification of hepatocytic proliferation in the laboratory mouse. A comparative study using immunohistochemical detection of bromodeoxyuridine (BrdU) incorporation and proliferating cell nuclear antigen (PCNA) expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Switching from alpha 1- to beta-subtypes in adrenergic response during primary culture of adult-rat hepatocytes as affected by the cell-to-cell interaction through plasma membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

The v-raf oncogene enhances tumorigenicity and suppresses differentiation in vivo in a rat hepatocyte cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Tyrosine kinase growth factor receptors but not seven-membrane-spanning receptors or phorbol esters activate mitogen-activated protein kinase in rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Ethanol enhances growth factor activation of mitogen-activated protein kinases by a protein kinase C-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

A naturally occurring estrogen receptor mutation results in increased estrogenicity of a tamoxifen analog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Nerve growth factor binding sites on hepatic parenchymal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Function and evolution in the NGF family and its receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

5 June 2018

Time course comparison of cell-cycle protein expression following partial hepatectomy and WY14,643-induced hepatic cell proliferation in F344 rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

18 August 2018

Local injection of nerve growth factor (NGF) triggers degranulation of mast cells in rat paw.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

18 August 2018

Cooperating oncogenes converge to regulate cyclin/cdk complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

18 August 2018

Inverse regulation of hepatic alpha 1B- and beta 2-adrenergic receptors. Cellular mechanisms and physiological implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219295

18 August 2018

Expression of the c-raf protooncogene, gamma-glutamyltranspeptidase, and gap junction protein in rat liver neoplasms

1 reference

https://pubmed.ncbi.nlm.nih.gov/9494119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/9494119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Probing the structure-function relationship of nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9494119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation of PC12 cells in response to a cAMP analogue is accompanied by sustained activation of mitogen-activated protein kinase. Comparison with the effects of insulin, growth factors and phorbol esters

1 reference

https://pubmed.ncbi.nlm.nih.gov/9494119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/9494119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9494119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of epsilon-protein kinase C enhances nerve growth factor-induced phosphorylation of mitogen-activated protein kinases and neurite outgrowth

1 reference

https://pubmed.ncbi.nlm.nih.gov/9494119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth factor dependence of progression through G1 and S phases of adult rat hepatocytes in vitro. Evidence of a mitogen restriction point in mid-late G1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9494119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of Raf isozymes by growth versus differentiation inducing factors in PC12 pheochromocytoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9494119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of ethanol on hepatocyte growth factor-induced DNA synthesis and Ca2+ mobilization in rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9494119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro regulation of insulin release and biosynthesis of fetal rat pancreatic cells explanted on pregnancy day 16

1 reference

https://pubmed.ncbi.nlm.nih.gov/9494119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disregulation of mitotic checkpoints and regulatory proteins following acute expression of SV40 large T antigen in diploid human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9494119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9494119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor and fibroblast growth factor influence post-fusion expression of Na-channels in cultured rat skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/9494119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3301451

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9494119%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9494119%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9494119%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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