(Q41896456)

English

Myofilament Ca sensitization increases cytosolic Ca binding affinity, alters intracellular Ca homeostasis, and causes pause-dependent Ca-triggered arrhythmia.

scientific article published on 29 May 2012

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scholarly article

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2 February 2020

Myofilament Ca sensitization increases cytosolic Ca binding affinity, alters intracellular Ca homeostasis, and causes pause-dependent Ca-triggered arrhythmia (English)

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2 February 2020

Bjorn C. Knollmann

8

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2 February 2020

author name string

Tilmann Schober

1

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2 February 2020

Sabine Huke

2

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2 February 2020

Raghav Venkataraman

3

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2 February 2020

Oleksiy Gryshchenko

4

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2 February 2020

Dmytro Kryshtal

5

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2 February 2020

Hyun Seok Hwang

6

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2 February 2020

Franz J Baudenbacher

7

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2 February 2020

publication date

29 May 2012

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2 February 2020

Circulation Research

1 reference

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2 February 2020

111

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2 February 2020

2

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2 February 2020

170-179

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2 February 2020

Increased myofilament Ca2+-sensitivity and arrhythmia susceptibility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393041

5 June 2018

Myofilament Ca2+ sensitization causes susceptibility to cardiac arrhythmia in mice.

1 reference

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5 June 2018

Calcium and arrhythmogenesis

1 reference

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5 June 2018

What causes sudden death in heart failure?

1 reference

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5 June 2018

Intracellular Ca(2+) concentration and rate adaptation of the cardiac action potential

1 reference

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5 June 2018

THE INFLUENCE OF THE INTERVAL BETWEEN BEATS ON MYOCARDIAL CONTRACTILITY

1 reference

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5 June 2018

Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy

1 reference

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5 June 2018

Increased Ca2+-sensitivity of the contractile apparatus in end-stage human heart failure results from altered phosphorylation of contractile proteins

1 reference

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5 June 2018

Calcium and cardiac rhythms: physiological and pathophysiological

1 reference

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5 June 2018

Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy.

1 reference

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5 June 2018

Structure of the C-domain of human cardiac troponin C in complex with the Ca2+ sensitizing drug EMD 57033

1 reference

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5 June 2018

The molecular genetic basis for hypertrophic cardiomyopathy

1 reference

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5 June 2018

The effects of exogenous calcium buffers on the systolic calcium transient in rat ventricular myocytes

1 reference

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5 June 2018

Calcium fluxes involved in control of cardiac myocyte contraction

1 reference

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5 June 2018

Arrhythmias in the congenital long QT syndrome: how often is torsade de pointes pause dependent?

1 reference

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5 June 2018

Troponin C - troponin I interactions and molecular signalling in cardiac myofilaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393041

5 June 2018

Mutations in the genes for cardiac troponin T and alpha-tropomyosin in hypertrophic cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393041

5 June 2018

Intrinsic cytosolic calcium buffering properties of single rat cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393041

5 June 2018

Force-interval relations of twitches and cold contractures in rat cardiac trabeculae. Effect of ryanodine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393041

5 June 2018

Cellular mechanisms of early afterdepolarizations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393041

5 June 2018

F110I and R278C troponin T mutations that cause familial hypertrophic cardiomyopathy affect muscle contraction in transgenic mice and reconstituted human cardiac fibers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393041

18 August 2018

Hypertrophy, fibrosis, and sudden cardiac death in response to pathological stimuli in mice with mutations in cardiac troponin T.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393041

18 August 2018

Cardiac troponin T isoforms affect the Ca(2+) sensitivity of force development in the presence of slow skeletal troponin I: insights into the role of troponin T isoforms in the fetal heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393041

18 August 2018

Clinical features of hypertrophic cardiomyopathy caused by an Arg278Cys missense mutation in the cardiac troponin T gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393041

18 August 2018

Prevalence and spectrum of thin filament mutations in an outpatient referral population with hypertrophic cardiomyopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393041

18 August 2018

Familial hypertrophic cardiomyopathy-linked mutant troponin T causes stress-induced ventricular tachycardia and Ca2+-dependent action potential remodeling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393041

18 August 2018

Inotropic stimulation induces cardiac dysfunction in transgenic mice expressing a troponin T (I79N) mutation linked to familial hypertrophic cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393041

18 August 2018

The pause that refreshes, or does it? Mechanisms in torsades de pointes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393041

18 August 2018

Studies of the contractility of mammalian myocardium at low rates of stimulation

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Stereoselective actions of thiadiazinones on canine cardiac myocytes and myofilaments

1 reference

https://pubmed.ncbi.nlm.nih.gov/22647877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Mutant Tropomyosin That Causes Hypertrophic Cardiomyopathy Is Expressed In Vivo and Associated With an Increased Calcium Sensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22647877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel, rapid and reversible method to measure Ca buffering and time-course of total sarcoplasmic reticulum Ca content in cardiac ventricular myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22647877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of pause-induced torsade de pointes in long QT syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/22647877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effect of troponin T mutations on the inotropic responsiveness of mouse hearts--role of myofilament Ca2+ sensitivity increase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22647877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Action potential characterization in intact mouse heart: steady-state cycle length dependence and electrical restitution

1 reference

https://pubmed.ncbi.nlm.nih.gov/22647877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early Exercise Training Normalizes Myofilament Function and Attenuates Left Ventricular Pump Dysfunction in Mice With a Large Myocardial Infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22647877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

Magnitude of left ventricular hypertrophy and risk of sudden death in hypertrophic cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22647877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiology of Hypertrophic Cardiomyopathy–Related Death

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Observations on the onset of torsade de pointes arrhythmias in the acquired long QT syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/22647877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of low concentrations of caffeine on spontaneous Ca release in isolated rat ventricular myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22647877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal contractile function in transgenic mice expressing a familial hypertrophic cardiomyopathy-linked troponin T (I79N) mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22647877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypertrophic cardiomyopathy: histopathological features of sudden death in cardiac troponin T disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22647877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/CIRCRESAHA.112.270041

1 reference

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2 February 2020

release_vkw3utznlbafjd7gd47zbsnhcm

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24 November 2022

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mapped directly with Wikidata item

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Europe PubMed Central

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2 February 2020

1 reference

Europe PubMed Central

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2 February 2020

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