(Q41898625)

13 October 2017

Mitochondrial aspartate aminotransferase catalyses cysteine S-conjugate beta-lyase reactions (English)

1 reference

13 October 2017

Arthur J L Cooper

1

1 reference

13 October 2017

Sam A Bruschi

series ordinal

2

1 reference

13 October 2017

Ana Iriarte

series ordinal

3

1 reference

13 October 2017

Marino Martinez-Carrion

series ordinal

4

1 reference

13 October 2017

language of work or name

English

0 references

publication date

1 November 2002

1 reference

13 October 2017

1 reference

13 October 2017

368

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13 October 2017

Pt 1

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13 October 2017

253-261

1 reference

Toxic, halogenated cysteine S-conjugates and targeting of mitochondrial enzymes of energy metabolism

13 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Immunogold localization of mitochondrial aspartate aminotransferase in mitochondria and on the cell surface in normal rat tissues

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Mitochondrial stress protein recognition of inactivated dehydrogenases during mammalian cell death

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

The nephrotoxicity and hepatotoxicity of 1,1,2,2-tetrafluoroethyl-L-cysteine in the rat.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Mechanisms of cysteine S-conjugate beta-lyases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Protein folding in a cell-free translation system. The fate of the precursor to mitochondrial aspartate aminotransferase.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Cysteine conjugate toxicity in a human cell line: correlation with C-S lyase activity in human hepatic tissue

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Enzymology of cysteine S-conjugate beta-lyases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Formation and fate of nephrotoxic and cytotoxic glutathione S-conjugates: cysteine conjugate beta-lyase pathway

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Mitochondrial HSP60 (P1 protein) and a HSP70-like protein (mortalin) are major targets for modification during S-(1,1,2,2-tetrafluoroethyl)-L-cysteine-induced nephrotoxicity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Chemistry of the inactivation of cytosolic aspartate aminotransferase by serine O-sulfate

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Use of beta-methylene-D,L-aspartate to assess the role of aspartate aminotransferase in cerebral oxidative metabolism

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Distinctions in the Equilibrium Kinetic Constants of the Mitochondrial and Supernatant Isozymes of Aspartate Transaminase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Labeling of the active site of cytoplasmic aspartate aminotransferase by β-chloro-L-alanine

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Evidence of phenylalanine transaminase activity in the isoenzymes of aspartate transaminase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

The reaction of L-serine O-sulfate with aspartate aminotransferase.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

A purified cysteine conjugate beta-lyase from rat kidney cytosol. Requirement for an alpha-keto acid or an amino acid oxidase for activity and identity with soluble glutamine transaminase K.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Separate enzymatic microassays for aspartate aminotransferase isoenzymes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Nephrotoxicity of mercapturic acids of three structurally related 2,2-difluoroethylenes in the rat. Indications for different bioactivation mechanisms

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Cysteine conjugate toxicity, metabolism, and binding to macromolecules in isolated rat kidney mitochondria

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Bioactivation of xenobiotics by formation of toxic glutathione conjugates

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

beta-elimination of beta-halo substrates by D-amino acid transaminase associated with inactivation of the enzyme. Trapping of a key intermediate in the reaction

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Distribution of two aminotransferases and D-amino acid oxidase within the nephron of young and adult rats

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Purification, properties, and identity of liver mitochondrial tyrosine aminotransferase.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

KINETIC STUDIES OF GLUTAMIC OXALOACETIC TRANSAMINASE ISOZYMES.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Mitochondrial aconitase modification, functional inhibition, and evidence for a supramolecular complex of the TCA cycle by the renal toxicant S-(1,1,2,2-tetrafluoroethyl)-L-cysteine

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Co-purification of mitochondrial HSP70 and mature protein disulfide isomerase with a functional rat kidney high-M(r) cysteine S-conjugate beta-lyase

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Mercapturic acids (N-acetylcysteine S-conjugates) as endogenous substrates for the renal organic anion transporter-1.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

Rationalisation of the C-S lyase activity of aspartate amino transferase.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222959

The C-S lysis of L-cysteine conjugates by aspartate and alanine aminotransferase enzymes

18 August 2018

1 reference

12 December 2020

Novel sources of mammalian C-S lyase activity

1 reference

12 December 2020

Inactivation of brain and kidney aspartate aminotransferases by S-(1,2,-dichlorovinyl)-L-cysteine and by S-(1,1,2,2,-tetrafluoroethyl)-L-cysteine

1 reference

12 December 2020

Insight into the conformation of protein folding intermediate(s) trapped by GroEL

1 reference

12 December 2020

Glutathione-dependent bioactivation of haloalkenes

1 reference

12 December 2020

2-oxoacid dehydrogenases of rat liver mitochondria as the site of action of S-(1,2 Dichlorovinyl)-l-Cysteine and S-(1,2 dichlorovinyl)-3-mercaptopropionic acid

1 reference

12 December 2020

The Protective Effect of Thiosulfate upon the Inactivation of Aspartate. Aminotransferase by Aminoacrylic-Acid-Producing Substrates

1 reference

12 December 2020

Formate-induced labeling of the active site of aspartate aminotransferase by beta-chloro-L-alanine

1 reference

12 December 2020

Glutamate-malate metabolism in liver mitochondria. A model constructed on the basis of mitochondrial levels of enzymes, specificity, dissociation constants, and stoichiometry of hetero-enzyme complexes

1 reference

12 December 2020

Renal transtubular transport of mercapturic acid in vivo

1 reference

12 December 2020

Role of the malate--aspartate shuttle in renal sodium transport in the rat

1 reference

12 December 2020

Metabolic coordination of liver and kidney in mercapturic acid biosynthesis in vivo

1 reference

12 December 2020

A novel reaction of the coenzyme of glutamate decarboxylase with L-serine O-sulfate

1 reference

12 December 2020

Inhibition of select mitochondrial enzymes in PC12 cells exposed to S-(1,1,2,2-tetrafluoroethyl)-L-cysteine

1 reference

12 December 2020

Macromolecular interactions: tracing the roots

1 reference

12 December 2020

Immunohistochemical localization of the acylases that catalyze the deacetylation of N-acetyl-L-cysteine and haloalkene-derived mercapturates

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ20020531

1 reference

13 October 2017

1 reference

13 October 2017

PubMed publication ID

12137566

1 reference