(Q41901416)

English

Interleukin-6 is elevated in synovial fluid of patients with focal cartilage defects and stimulates cartilage matrix production in an in vitro regeneration model

scientific article published on 3 December 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Interleukin-6 is elevated in synovial fluid of patients with focal cartilage defects and stimulates cartilage matrix production in an in vitro regeneration model (English)

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

1 reference

based on heuristic

inferred from title

Laura B Creemers

10

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

author name string

Anika I Tsuchida

1

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Michiel Beekhuizen

2

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Marijn Rutgers

3

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Gerjo J V M van Osch

4

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Joris E J Bekkers

5

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Arjan G J Bot

6

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Bernd Geurts

7

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Wouter J A Dhert

8

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Daniel B F Saris

9

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

publication date

3 December 2012

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Arthritis Research and Therapy

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

14

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

6

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

R262

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

https://scigraph.springernature.com/pub.10.1186/ar4107

0 references

COX-2-selective NSAIDs and risk of hip or knee replacements: a population-based case-control study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

2012 update of the 2008 American College of Rheumatology recommendations for the use of disease-modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Interleukin-7 levels in synovial fluid increase with age and MMP-1 levels decrease with progression of osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

The pathogenesis of rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Five-year outcome of characterized chondrocyte implantation versus microfracture for symptomatic cartilage defects of the knee: early treatment matters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Inflammation in osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

The effects of adipokines on cartilage and meniscus catabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Metabolic labeling of chondrocytes for the quantitative analysis of the interleukin-1-beta-mediated modulation of their intracellular and extracellular proteomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

The role of synovial fluid markers of catabolism and anabolism in osteoarthritis, rheumatoid arthritis and asymptomatic organ donors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Effects of high mobility group box protein-1, interleukin-1β, and interleukin-6 on cartilage matrix metabolism in three-dimensional equine chondrocyte cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

GP130 cytokines and bone remodelling in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Humanized anti-interleukin-6-receptor antibody (tocilizumab) monotherapy is more effective in slowing radiographic progression in patients with rheumatoid arthritis at high baseline risk for structural damage evaluated with levels of biomarkers, rad

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Shear-induced interleukin-6 synthesis in chondrocytes: roles of E prostanoid (EP) 2 and EP3 in cAMP/protein kinase A- and PI3-K/Akt-dependent NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Prostaglandin E2 induces interleukin-6 expression in human chondrocytes via cAMP/protein kinase A- and phosphatidylinositol 3-kinase-dependent NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Role for interleukin-6 in structural joint damage and systemic bone loss in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

The role of proinflammatory cytokines in the generation and maintenance of joint pain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Focal cartilage defects in the knee impair quality of life as much as severe osteoarthritis: a comparison of knee injury and osteoarthritis outcome score in 4 patient categories scheduled for knee surgery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

The impact of chronic inflammation on the growing skeleton: lessons from interleukin-6 transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Chondrocyte viability is higher after prolonged storage at 37 degrees C than at 4 degrees C for osteochondral grafts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Interleukin-6 subfamily cytokines and rheumatoid arthritis: role of antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Diagnostic utility of cytokine biomarkers in the evaluation of acute knee pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Evaluation of anti-IL-6 monoclonal antibody therapy using murine type II collagen-induced arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Decreased lubricin concentrations and markers of joint inflammation in the synovial fluid of patients with anterior cruciate ligament injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Human articular chondrocytes produce IL-7 and respond to IL-7 with increased production of matrix metalloproteinase-13.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

The effect of synovial fluid from injured knee joints on in vitro chondrogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Viability of human chondrocytes in an ex vivo model in relation to temperature and cartilage depth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

NF-kappa B mediates the stimulation of cytokine and chemokine expression by human articular chondrocytes in response to fibronectin fragments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Differential regulation of chondrocyte metabolism by oncostatin M and interleukin-6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Cytokine production in the infrapatellar fat pad: another source of cytokines in knee synovial fluids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Simultaneous detection of 15 human cytokines in a single sample of stimulated peripheral blood mononuclear cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

JAK/STAT but not ERK1/ERK2 pathway mediates interleukin (IL)-6/soluble IL-6R down-regulation of Type II collagen, aggrecan core, and link protein transcription in articular chondrocytes. Association with a down-regulation of SOX9 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

No consent should be needed for using leftover body material for scientific purposes. For.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Visualization of postmortem chondrocyte damage by vital staining and confocal laser scanning 3D microscopy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Synergistic effects of glycoprotein 130 binding cytokines in combination with interleukin-1 on cartilage collagen breakdown

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

IL-6 and its soluble receptor augment aggrecanase-mediated proteoglycan catabolism in articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Correlation between osteoarthritic cartilage damage and levels of proteinases and proteinase inhibitors in synovial fluid from the knee joint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Interleukin-6 reduces cartilage destruction during experimental arthritis. A study in interleukin-6-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Effects of human knee synovial fluid on chondrogenesis in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

A macrophage-derived factor required by plasmacytomas for survival and proliferation in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

5 June 2018

Chondrogenic potential of articular chondrocytes depends on their original location

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

18 August 2018

The infrapatellar fat pad of patients with osteoarthritis has an inflammatory phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

18 August 2018

Circulating levels of IL-6 and TNF-α are associated with knee radiographic osteoarthritis and knee cartilage loss in older adults.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

18 August 2018

Cytokine-induced increases in ADAMTS-4 messenger RNA expression do not lead to increased aggrecanase activity in ADAMTS-5-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

18 August 2018

The infrapatellar fat pad in knee osteoarthritis: an important source of interleukin-6 and its soluble receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

18 August 2018

Desirable effect of combination therapy with high molecular weight hyaluronate and NSAIDs on MMP production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

18 August 2018

Local cytokine profiles in knee osteoarthritis: elevated synovial fluid interleukin-15 differentiates early from end-stage disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

18 August 2018

IL-6/sIL-6R trans-signalling, but not TNF-alpha induced angiogenesis in a HUVEC and synovial cell co-culture system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

18 August 2018

Discoidin domain receptor 2 mediates the collagen II-dependent release of interleukin-6 in primary human chondrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

18 August 2018

Joint fluid antioxidants are decreased in osteoarthritic joints compared to joints with macroscopically intact cartilage and subacute injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

18 August 2018

Elevated IL-6 levels in the synovial fluid of osteoarthritis patients stem from plasma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

18 August 2018

Postmortem biochemical examination of synovial fluid--a preliminary study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

18 August 2018

Oncostatin M (OSM) stimulates resorption and inhibits synthesis of proteoglycan in porcine articular cartilage explants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

18 August 2018

IL-1 beta and IL-6 selectively induce transforming growth factor-beta isoforms in human articular chondrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

18 August 2018

A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674617

18 August 2018

Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concentrations and origins of soluble interleukin 6 receptor-alpha in serum and synovial fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved multiplex immunoassay performance in human plasma and synovial fluid following removal of interfering heterophilic antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of sample handling on the stability of interleukin 6, tumour necrosis factor-alpha and leptin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A critical role for collagen II in cartilage matrix degradation: collagen II induces pro-inflammatory cytokines and MMPs in primary human chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid and sustained improvement in bone and cartilage turnover markers with the anti-interleukin-6 receptor inhibitor tocilizumab plus methotrexate in rheumatoid arthritis patients with an inadequate response to methotrexate: results from a substudy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine profiling in acute anterior cruciate ligament injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catabolic factors and osteoarthritis-conditioned medium inhibit chondrogenesis of human mesenchymal stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 plays an essential role in hypoxia-inducible factor 2α-induced experimental osteoarthritic cartilage destruction in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Male IL-6 gene knock out mice developed more advanced osteoarthritis upon aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin (IL)-6 and its soluble receptor induce TIMP-1 expression in synoviocytes and chondrocytes, and block IL-1-induced collagenolytic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoarthritic synovial tissue inhibition of proteoglycan production in human osteoarthritic knee cartilage: Establishment and characterization of a long-term cartilage-synovium coculture

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of IL-6 and soluble IL-6 receptor on the expression of cartilage matrix proteins in human chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of exogenous IL-1 beta, TNF alpha, IL-6, IL-8 and LIF on cytokine production by human articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of interleukin-1, tumor necrosis factor alpha, and interleukin-6 in cartilage proteoglycan metabolism and destruction. Effect of in situ blocking in murine antigen- and zymosan-induced arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postmortem analysis of synovial fluid and vitreous humour for determination of death interval: A comparative study

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of IL-6 and its soluble receptor on proteoglycan synthesis and NO release by human articular chondrocytes: comparison with IL-1. Modulation by dexamethasone

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-6 production by human articular chondrocytes. Modulation of its synthesis by cytokines, growth factors, and hormones in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: results from the double-blind treatment phase of a randomized placebo-controlled trial of tocilizumab safety and prevention of s

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-1beta induction of IL-6 and LIF in normal articular human chondrocytes involves the ERK, p38 and NFkappaB signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 (IL-6) and/or soluble IL-6 receptor down-regulation of human type II collagen gene expression in articular chondrocytes requires a decrease of Sp1.Sp3 ratio and of the binding activity of both factors to the COL2A1 promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/23206933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

ResearchGate publication ID

0 references

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