(Q41901707)

English

In silico children and the glass mouse model: clinical trial simulations to identify and individualize optimal isoniazid doses in children with tuberculosis

scientific article published on 22 November 2010

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scholarly article

1 reference

Europe PubMed Central

13 October 2017

In silico children and the glass mouse model: clinical trial simulations to identify and individualize optimal isoniazid doses in children with tuberculosis (English)

1 reference

Europe PubMed Central

13 October 2017

1 reference

based on heuristic

inferred from title

0 references

4

1 reference

Europe PubMed Central

13 October 2017

author name string

Prakash M Jeena

1

1 reference

Europe PubMed Central

13 October 2017

William R Bishai

2

1 reference

Europe PubMed Central

13 October 2017

Jotam G Pasipanodya

3

1 reference

Europe PubMed Central

13 October 2017

language of work or name

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publication date

22 November 2010

1 reference

Europe PubMed Central

13 October 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

13 October 2017

55

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Europe PubMed Central

13 October 2017

539-545

1 reference

Europe PubMed Central

13 October 2017

2

1 reference

Europe PubMed Central

13 October 2017

An oracle: antituberculosis pharmacokinetics-pharmacodynamics, clinical correlation, and clinical trial simulations to predict the future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Clinical and toxicodynamic evidence that high-dose pyrazinamide is not more hepatotoxic than the low doses currently used

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Practical, individualized dosing: 21st century therapeutics and the clinical pharmacometrician

1 reference

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5 June 2018

New susceptibility breakpoints for first-line antituberculosis drugs based on antimicrobial pharmacokinetic/pharmacodynamic science and population pharmacokinetic variability

1 reference

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Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB.

1 reference

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A simple in vitro PK/PD model system to determine time-kill curves of drugs against Mycobacteria

1 reference

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The in silico child: using simulation to guide pediatric drug development and manage pediatric pharmacotherapy.

1 reference

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Pharmacokinetics-pharmacodynamics of pyrazinamide in a novel in vitro model of tuberculosis for sterilizing effect: a paradigm for faster assessment of new antituberculosis drugs

1 reference

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Population modeling and Monte Carlo simulation study of the pharmacokinetics and antituberculosis pharmacodynamics of rifampin in lungs

1 reference

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5 June 2018

Paediatric tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Integrating pharmacokinetics, pharmacodynamics and pharmacogenomics to predict outcomes in antibacterial therapy

1 reference

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5 June 2018

The Monte Carlo method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

NAT2 6A, a haplotype of the N-acetyltransferase 2 gene, is an important biomarker for risk of anti-tuberculosis drug-induced hepatotoxicity in Japanese patients with tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Interpretation of antibiotic concentration ratios measured in epithelial lining fluid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Correlation of the MIC and dose/MIC ratio of fluconazole to the therapeutic response of patients with mucosal candidiasis and candidemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Isoniazid bactericidal activity and resistance emergence: integrating pharmacodynamics and pharmacogenomics to predict efficacy in different ethnic populations

1 reference

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5 June 2018

Fluconazole MIC and the fluconazole dose/MIC ratio correlate with therapeutic response among patients with candidemia.

1 reference

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5 June 2018

Isoniazid pharmacokinetics in children treated for respiratory tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Should we use N-acetyltransferase type 2 genotyping to personalize isoniazid doses?

1 reference

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Tuberculous meningitis and miliary tuberculosis: the Rich focus revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Isoniazid pharmacokinetics-pharmacodynamics in an aerosol infection model of tuberculosis

1 reference

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Relationship of MIC and bactericidal activity to efficacy of vancomycin for treatment of methicillin-resistant Staphylococcus aureus bacteremia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

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Activation of pyrazinamide and nicotinamide in acidic environments in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Therapeutic drug monitoring in the treatment of tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Effects of gender, AIDS, and acetylator status on intrapulmonary concentrations of isoniazid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Extra-pulmonary tuberculosis in children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Role of acid pH and deficient efflux of pyrazinoic acid in unique susceptibility of Mycobacterium tuberculosis to pyrazinamide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Population pharmacokinetic modeling of isoniazid, rifampin, and pyrazinamide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Pharmacodynamics of a fluoroquinolone antimicrobial agent in a neutropenic rat model of Pseudomonas sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Antibiotic entry into human polymorphonuclear leukocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Kinetics of isoniazid transfer into cerebrospinal fluid in patients with tuberculous meningitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

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Evolution of the P450 gene superfamily: animal-plant 'warfare', molecular drive and human genetic differences in drug oxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Cerebrospinal fluid isoniazid concentrations in children with tuberculous meningitis: the influence of dosage and acetylation status

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

5 June 2018

Isoniazid plasma concentrations in a cohort of South African children with tuberculosis: implications for international pediatric dosing guidelines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028779

18 August 2018

Antimicrobial activity of cefepime and rifampicin in cerebrospinal fluid in vitro.

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Low-dose inhaled versus standard dose oral form of anti-tubercular drugs: concentrations in bronchial epithelial lining fluid, alveolar macrophage and serum.

1 reference

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18 August 2018

Selection of a moxifloxacin dose that suppresses drug resistance in Mycobacterium tuberculosis, by use of an in vitro pharmacodynamic infection model and mathematical modeling

1 reference

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Accessory gene regulator group II polymorphism in methicillin-resistant Staphylococcus aureus is predictive of failure of vancomycin therapy

1 reference

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Dosages of anti-tuberculosis medications in the national tuberculosis programs of Kenya, Nepal, and Senegal.

1 reference

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18 August 2018

Isoniazid pharmacokinetics in children according to acetylator phenotype

1 reference

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Uptake of antibiotics by human alveolar macrophages.

1 reference

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Antimicrobial Resistance: Pharmacokinetics‐Pharmacodynamics of Antimicrobial Therapy: It’s Not Just for Mice Anymore

1 reference

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2 December 2018

In vitro protein binding characteristics of isoniazid, rifampicin, and pyrazinamide to whole plasma, albumin, and alpha-1-acid glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/21098246

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum and cerebrospinal fluid concentrations of rifampicin at two dose levels in children with tuberculous meningitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21098246

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Multicenter evaluation of broth microdilution test, BrothMIC MTB, to determine minimum inhibitory concentrations (MICs) of antimicrobial agents for Mycobacterium tuberculosis--evaluation of interlaboratory precision and interpretive compatibility w

1 reference

https://pubmed.ncbi.nlm.nih.gov/21098246

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Guidance for National Tuberculosis Programmes on the management of tuberculosis in children. Chapter 1: introduction and diagnosis of tuberculosis in children

1 reference

https://pubmed.ncbi.nlm.nih.gov/21098246

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.00763-10

1 reference

Europe PubMed Central

13 October 2017

release_aa7o6nchojhwnfprbkbdcjfcsm

1 reference

https://api.fatcat.wiki/v0/release/aa7o6nchojhwnfprbkbdcjfcsm

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

13 October 2017

1 reference

Europe PubMed Central

13 October 2017

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