(Q41901986)

English

Expression of Nav1.7 in DRG neurons extends from peripheral terminals in the skin to central preterminal branches and terminals in the dorsal horn

scientific article published on 7 November 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Expression of Nav1.7 in DRG neurons extends from peripheral terminals in the skin to central preterminal branches and terminals in the dorsal horn (English)

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

author name string

Joel A Black

1

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Noémie Frézel

2

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Sulayman D Dib-Hajj

3

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Stephen G Waxman

4

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

publication date

7 November 2012

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

8

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

82

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Reduction of voltage gated sodium channel protein in DRG by vector mediated miRNA reduces pain in rats with painful diabetic neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Intra- and interfamily phenotypic diversity in pain syndromes associated with a gain-of-function variant of NaV1.7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

The roles of sodium channels in nociception: implications for mechanisms of neuropathic pain

1 reference

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5 June 2018

Gain of function NaV1.7 mutations in idiopathic small fiber neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Nav1.7 is the predominant sodium channel in rodent olfactory sensory neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Loss-of-function mutations in sodium channel Nav1.7 cause anosmia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Sodium-calcium exchanger and multiple sodium channel isoforms in intra-epidermal nerve terminals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Mutations at opposite ends of the DIII/S4-S5 linker of sodium channel Na V 1.7 produce distinct pain disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Sodium channels in normal and pathological pain

1 reference

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5 June 2018

Targeting ion channels for drug discovery.

1 reference

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5 June 2018

ERK1/2 mitogen-activated protein kinase phosphorylates sodium channel Na(v)1.7 and alters its gating properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Voltage-gated sodium channels: therapeutic targets for pain

1 reference

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5 June 2018

Sensory neuron voltage-gated sodium channels as analgesic drug targets

1 reference

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5 June 2018

Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitable

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Comparative study of the distribution of the alpha-subunits of voltage-gated sodium channels in normal and axotomized rat dorsal root ganglion neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Continuous delta-opioid receptor activation reduces neuronal voltage-gated sodium channel (NaV1.7) levels through activation of protein kinase C in painful diabetic neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

From genes to pain: Na v 1.7 and human pain disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Changes in the expression of NaV1.7, NaV1.8 and NaV1.9 in a distinct population of dorsal root ganglia innervating the rat knee joint in a model of chronic inflammatory joint pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Distribution of the voltage-gated sodium channel Na(v)1.7 in the rat: expression in the autonomic and endocrine systems.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

A stop codon mutation in SCN9A causes lack of pain sensation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

An SCN9A channelopathy causes congenital inability to experience pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

A single sodium channel mutation produces hyper- or hypoexcitability in different types of neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Sporadic onset of erythermalgia: a gain-of-function mutation in Nav1.7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

SCN9A mutations define primary erythermalgia as a neuropathic disorder of voltage gated sodium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Early painful diabetic neuropathy is associated with differential changes in tetrodotoxin-sensitive and -resistant sodium channels in dorsal root ganglion neurons in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Accumulation of PN1 and PN3 sodium channels in painful human neuroma-evidence from immunocytochemistry

1 reference

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Response properties of mechanoreceptors and nociceptors in mouse glabrous skin: an in vivo study

1 reference

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Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses

1 reference

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Differential expression of the mRNA for the vanilloid receptor subtype 1 in cells of the adult rat dorsal root and nodose ganglia and its downregulation by axotomy

1 reference

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5 June 2018

Slow closed-state inactivation: a novel mechanism underlying ramp currents in cells expressing the hNE/PN1 sodium channel.

1 reference

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5 June 2018

Tackling pain at the source: new ideas about nociceptors

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The axonal membrane protein Caspr, a homologue of neurexin IV, is a component of the septate-like paranodal junctions that assemble during myelination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Structure and functional expression of a new member of the tetrodotoxin-sensitive voltage-activated sodium channel family from human neuroendocrine cells

1 reference

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5 June 2018

Electrical properties of rat dorsal root ganglion neurones with different peripheral nerve conduction velocities.

1 reference

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Synaptophysin and synapsin I as tools for the study of the exo-endocytotic cycle

1 reference

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NeuN, a neuronal specific nuclear protein in vertebrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

5 June 2018

Sodium channel Na(v)1.7 is essential for lowering heat pain threshold after burn injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

18 August 2018

Reduced conduction failure of the main axon of polymodal nociceptive C-fibres contributes to painful diabetic neuropathy in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

18 August 2018

Nav1.7 accumulates and co-localizes with phosphorylated ERK1/2 within transected axons in early experimental neuromas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

18 August 2018

Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

18 August 2018

Decrease in inflammatory hyperalgesia by herpes vector-mediated knockdown of Nav1.7 sodium channels in primary afferents

1 reference

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18 August 2018

Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd

1 reference

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18 August 2018

Ibuprofen blocks changes in Na v 1.7 and 1.8 sodium channels associated with complete Freund's adjuvant-induced inflammation in rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

18 August 2018

Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

18 August 2018

Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

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Axoplasmic transport block reduces ectopic impulse generation in injured peripheral nerves

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517774

18 August 2018

Sensory and electrophysiological properties of guinea-pig sensory neurones expressing Nav 1.7 (PN1) Na+ channel alpha subunit protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/23134641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microelectrode recordings from transected nerves in amputees with phantom limb pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/23134641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-L and peripherin immunoreactivities define distinct classes of rat sensory ganglion cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23134641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Na(v)1.7 sodium channel expression in human lingual nerve neuromas

1 reference

https://pubmed.ncbi.nlm.nih.gov/23134641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nav1.7-related small fiber neuropathy: impaired slow-inactivation and DRG neuron hyperexcitability

1 reference

https://pubmed.ncbi.nlm.nih.gov/23134641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1744-8069-8-82

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

ResearchGate publication ID

0 references

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