(Q41903223)

English

Betaxolol, a beta(1)-adrenoceptor antagonist, reduces Na(+) influx into cortical synaptosomes by direct interaction with Na(+) channels: comparison with other beta-adrenoceptor antagonists

scientific article published on June 2000

In more languages

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Betaxolol, a beta(1)-adrenoceptor antagonist, reduces Na(+) influx into cortical synaptosomes by direct interaction with Na(+) channels: comparison with other beta-adrenoceptor antagonists (English)

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

author name string

G Chidlow

1

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

J Melena

2

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

N N Osborne

3

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

language of work or name

0 references

publication date

1 June 2000

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

130

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

4

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

759-766

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

The potential of neuroprotection in glaucoma treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Systemic and ocular vascular roles of the antiglaucoma agents beta-adrenergic antagonists and Ca2+ entry blockers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

An experimental basis for implicating excitotoxicity in glaucomatous optic neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Neuroprotection in relation to retinal ischemia and relevance to glaucoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Neuroprotective strategies: voltage-gated Na+-channel down-modulation versus presynaptic glutamate release inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Ion channels as targets for neuroprotective agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Inhibition by propofol of [3H]-batrachotoxinin-A 20-alpha-benzoate binding to voltage-dependent sodium channels in rat cortical synaptosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Comparison of the ocular beta-blockers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Structure and function of voltage-dependent sodium channels: comparison of brain II and cardiac isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Topical ophthalmic beta blockers: a comparative review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Inhibitory action of betaxolol, a β‐selective adrenoceptor antagonist, on voltage‐dependent calcium channels in guinea‐pig artery and vein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Neuroprotective use-dependent blockers of Na+ and Ca2+ channels controlling presynaptic release of glutamate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Effects of some antianginal and vasodilating drugs on sodium influx and on the binding of 3H-batrachotoxinin-A 20-alpha-benzoate and 3H-tetracaine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Inhibitory effects of some cyclohexylaralkylamines related to perhexiline on sodium influx, binding of [3H]batrachotoxinin A 20-α-benzoate and [3H]nitrendipine and on guinea pig left atria contractions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

A rapid Percoll gradient procedure for isolation of synaptosomes directly from an S1 fraction: homogeneity and morphology of subcellular fractions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

The membrane stabilizing activity of beta-adrenoceptor ligands. Quantitative evaluation of the interaction of phenoxypropanolamines with the [3H]batrachotoxinin A 20-alpha-benzoate binding site on voltage-sensitive sodium channels in rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Ocular betaxolol. A review of its pharmacological properties, and therapeutic efficacy in glaucoma and ocular hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Influence of betaxolol and timolol on the visual fields of patients with glaucoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Lipophilicity influence on conjunctival drug penetration in the pigmented rabbit: a comparison with corneal penetration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Tertiary and quaternary local anesthetics protect CNS white matter from anoxic injury at concentrations that do not block excitability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na(+)-Ca2+ exchanger.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

5 June 2018

Betaxolol, a beta1-adrenoceptor antagonist, has an affinity for L-type Ca2+ channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

18 August 2018

Ca2+ channel antagonists and neuroprotection from cerebral ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

18 August 2018

The importance of voltage-dependent sodium channels in cerebral ischaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

18 August 2018

Neuroprotection--rationale for pharmacological modulation of Na(+)-channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

18 August 2018

A comparison of the effects of betaxolol, timolol, and pilocarpine on visual function in patients with open-angle glaucoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

18 August 2018

Differential expression of sodium channel genes in retinal ganglion cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

18 August 2018

Blockade of voltage-sensitive sodium channels by NS-7, a novel neuroprotective compound, in the rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

18 August 2018

In vivo and in vitro experiments show that betaxolol is a retinal neuroprotective agent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

18 August 2018

Anoxic injury of rat optic nerve: ultrastructural evidence for coupling between Na+ influx and Ca(2+)-mediated injury in myelinated CNS axons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

18 August 2018

Intestinal permeability of ophthalmic beta-blockers for predicting ocular permeability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

18 August 2018

Inhibition of binding of [3H]batrachotoxinin A 20-alpha-benzoate to sodium channels by local anesthetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572129

18 August 2018

Ion flux studies of voltage-sensitive sodium channels in synaptic nerve-ending particles

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of various antianginal drugs on sodium influx in rat brain synaptosomes and in rat heart muscle cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Longterm effect of topical beta-blockers on intraocular pressure and visual field sensitivity in ocular hypertension and chronic open-angle glaucoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Longterm visual field follow-up of glaucoma patients treated with beta-blockers

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinal ganglion cell dysfunction induced by hypoxia and glutamate: potential neuroprotective effects of beta-blockers

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topically applied betaxolol attenuates NMDA-induced toxicity to ganglion cells and the effects of ischaemia to the retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0703369

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

ResearchGate publication ID

0 references

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