(Q41906637)

English

Controlled alteration of the shape and conformational stability of alpha-helical cell-lytic peptides: effect on mode of action and cell specificity.

scientific article published on August 2005

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scholarly article

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10 January 2020

Controlled alteration of the shape and conformational stability of alpha-helical cell-lytic peptides: effect on mode of action and cell specificity (English)

1 reference

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10 January 2020

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10 January 2020

Alessandro Tossi

7

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10 January 2020

author name string

Igor Zelezetsky

1

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10 January 2020

Ulrike Pag

3

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10 January 2020

Niv Papo

4

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10 January 2020

Yechiel Shai

5

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10 January 2020

Hans-Georg Sahl

6

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10 January 2020

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publication date

1 August 2005

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10 January 2020

Biochemical Journal

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10 January 2020

390

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10 January 2020

Pt 1

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10 January 2020

177-188

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10 January 2020

The relationship between peptide structure and antibacterial activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Immunotoxin therapy of hematologic malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Mode of action of membrane active antimicrobial peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Control of peptide conformation by the Thorpe-Ingold effect (C alpha-tetrasubstitution).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Antimicrobial peptides of multicellular organisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Barrel-stave model or toroidal model? A case study on melittin pores.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Amphipathic, alpha-helical antimicrobial peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Properties of cytotoxic peptide-formed ion channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Structural features of helical antimicrobial peptides: their potential to modulate activity on model membranes and biological cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Melittin activates endogenous phospholipase D during cytolysis of human monocytic leukemia cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Peptide antibiotics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Mode of action of linear amphipathic alpha-helical antimicrobial peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Activities of LL-37, a cathelin-associated antimicrobial peptide of human neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Modulation of membrane activity of amphipathic, antibacterial peptides by slight modifications of the hydrophobic moment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Pore formation and translocation of melittin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Peptides in membranes: tipping the balance of membrane stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Membrane pores induced by magainin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Cell membrane changes induced by the cytolytic peptide, melittin, are detectable by 90 degrees laser scatter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Mode of action of the antibacterial cecropin B2: a spectrofluorometric study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Induced conformational states of amphipathic peptides in aqueous/lipid environments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Membrane lipid phase as catalyst for peptide-receptor interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

5 June 2018

Identification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

18 August 2018

Kinetics of dye efflux and lipid flip-flop induced by delta-lysin in phosphatidylcholine vesicles and the mechanism of graded release by amphipathic, alpha-helical peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

18 August 2018

Bactericidal cationic peptides can also function as bacteriolysis-inducing agents mimicking beta-lactam antibiotics?; it is enigmatic why this concept is consistently disregarded.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

18 August 2018

In vitro activity and mode of action of diastereomeric antimicrobial peptides against bacterial clinical isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

18 August 2018

Interaction of antimicrobial peptides with lipopolysaccharides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

18 August 2018

New lytic peptides based on the D,L-amphipathic helix motif preferentially kill tumor cells compared to normal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

18 August 2018

Exploring peptide membrane interaction using surface plasmon resonance: differentiation between pore formation versus membrane disruption by lytic peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

18 August 2018

Analysis of the cytotoxicity of synthetic antimicrobial peptides on mouse leucocytes: implications for systemic use.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

18 August 2018

Position-dependent hydrophobicity of the antimicrobial magainin peptide affects the mode of peptide-lipid interactions and selective toxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

18 August 2018

Controls exerted by the Aib residue: helix formation and helix reversal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

18 August 2018

Analysis of antimicrobial peptide interactions with hybrid bilayer membrane systems using surface plasmon resonance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

18 August 2018

Folding of amphipathic alpha-helices on membranes: energetics of helix formation by melittin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

18 August 2018

Influence of preformed alpha-helix and alpha-helix induction on the activity of cationic antimicrobial peptides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

18 August 2018

Wide-spectrum antibiotic activity of synthetic, amphipathic peptides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

18 August 2018

The role of amphipathicity in the folding, self-association and biological activity of multiple subunit small proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

18 August 2018

Antimicrobial Peptides in Health and Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184573

2 December 2018

General aspects of peptide selectivity towards lipid bilayers and cell membranes studied by variation of the structural parameters of amphipathic helical model peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/15836439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphipathic alpha helical antimicrobial peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/15836439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms for the modulation of membrane bilayer properties by amphipathic helical peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/15836439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective lysis of bacteria but not mammalian cells by diastereomers of melittin: structure-function study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15836439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design of synthetic antimicrobial peptides based on sequence analogy and amphipathicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15836439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformation-dependent antibacterial activity of the naturally occurring human peptide LL-37

1 reference

https://pubmed.ncbi.nlm.nih.gov/15836439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Magainins as paradigm for the mode of action of pore forming polypeptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/15836439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of an antimicrobial peptide, magainin 2, with lipopolysaccharide-containing liposomes as a model for outer membranes of gram-negative bacteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/15836439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclization of a cytolytic amphipathic alpha-helical peptide and its diastereomer: effect on structure, interaction with model membranes, and biological function

1 reference

https://pubmed.ncbi.nlm.nih.gov/15836439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Action of antimicrobial peptides: two-state model

1 reference

https://pubmed.ncbi.nlm.nih.gov/15836439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ20042138

1 reference

Europe PubMed Central

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10 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15836439%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15836439%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

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