(Q41909315)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

The effects of nitroxyl (HNO) on soluble guanylate cyclase activity: interactions at ferrous heme and cysteine thiols (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

5

1 reference

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31 January 2020

Thomas W Miller

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Adrian J Hobbs

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

author name string

Melisa M Cherney

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Andrea J Lee

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Nestor E Francoleon

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

S Bruce King

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Katrina M Miranda

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Judith N Burstyn

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Jon M Fukuto

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

language of work or name

English

0 references

publication date

15 June 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

number of pages

9

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

volume

284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

issue

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

page(s)

21788-21796

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

Persistent susceptibility of cathepsin B to irreversible inhibition by nitroxyl (HNO) in the presence of endogenous nitric oxide

31 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Side effects of using nitrates to treat heart failure and the acute coronary syndromes, unstable angina and acute myocardial infarction

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Desensitization of soluble guanylyl cyclase, the NO receptor, by S-nitrosylation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

The pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NO

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Soluble guanylate cyclase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Hydrolysis of Acyloxy Nitroso Compounds Yields Nitroxyl (HNO)

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Coordination chemistry of the HNO ligand with hemes and synthetic coordination complexes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Positive inotropic and lusitropic effects of HNO/NO − in failing hearts: Independence from β-adrenergic signaling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Nitroxyl gets to the heart of the matter.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Nitroxyl and its anion in aqueous solutions: spin states, protic equilibria, and reactivities toward oxygen and nitric oxide

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Effects of agents that inactivate free radical NO (NO*) on nitroxyl anion-mediated relaxations, and on the detection of NO* released from the nitroxyl anion donor Angeli's salt

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Vascular smooth muscle relaxation mediated by nitric oxide donors: a comparison with acetylcholine, nitric oxide and nitroxyl ion

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

On the acidity and reactivity of HNO in aqueous solution and biological systems

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Differential actions of L-cysteine on responses to nitric oxide, nitroxyl anions and EDRF in the rat aorta

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Guanylate cyclase and the .NO/cGMP signaling pathway

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Nitric oxide-cyclic GMP signal transduction system.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Activation of purified soluble guanylate cyclase by protoporphyrin IX.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Electromagnetic properties of hemoproteins. V. Optical and electron paramagnetic resonance characteristics of nitric oxide derivatives of metalloporphyrin-apohemoprotein complexes.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Effects of thiol inhibitors on hepatic guanylate cylase activity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Oxidative-reductive modulation of guinea pig splenic cell guanylate cyclase activity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Activation of hepatic guanylate cyclase by N-methyl-N'-nitro-N-nitrosoguanidine. Effects of thiols, N-ethylmaleimide, and divalent cations

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Photolysis of the HNO adduct of myoglobin: transient generation of the aminoxyl radical

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Antioxidant actions of nitroxyl (HNO).

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Characterization of nitrosoalkane binding and activation of soluble guanylate cyclase

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Mass spectrometric analysis of nitroxyl-mediated protein modification: comparison of products formed with free and protein-based cysteines

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Theoretical reduction potentials for nitrogen oxides from CBS-QB3 energetics and (C)PCM solvation calculations

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Bonding in HNO-myoglobin as characterized by X-ray absorption and resonance raman spectroscopies

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Mechanisms of HNO and NO production from Angeli's salt: density functional and CBS-QB3 theory predictions

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Efficient trapping of HNO by deoxymyoglobin

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Fast nitroxyl trapping by ferric porphyrins.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Preparation of heme-free soluble guanylate cyclase

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

NO- activates soluble guanylate cyclase and Kv channels to vasodilate resistance arteries

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

1H NMR structure of the heme pocket of HNO-myoglobin

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Role of catalase in the smooth muscle relaxant actions of sodium azide and cyanamide.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Comparison of responses to novel nitric oxide donors in the feline pulmonary vascular bed.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Calcium ion downregulates soluble guanylyl cyclase activity: evidence for a two-metal ion catalytic mechanism

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Reaction between S-nitrosothiols and thiols: generation of nitroxyl (HNO) and subsequent chemistry.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Chemical oxidation of N-hydroxyguanidine compounds. Release of nitric oxide, nitroxyl and possible relationship to the mechanism of biological nitric oxide generation

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755905

Effect of nitroxyl on human platelets function

18 August 2018

1 reference

12 December 2020

The nitroxyl anion (HNO) is a potent dilator of rat coronary vasculature

1 reference

12 December 2020

Nitroxyl anion donor, Angeli's salt, does not develop tolerance in rat isolated aortae

1 reference

12 December 2020

Stereochemistry of low-spin cobalt porphyrins. I. Structure and bonding in a nitrosylcobalt porphyrin and their bearing on one rational model for the oxygenated protoheme

1 reference

12 December 2020

Reversible inactivation of guanylate cyclase by mixed disulfide formation

1 reference

12 December 2020

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates

1 reference

12 December 2020

Activation of purified guanylate cyclase by nitric oxide requires heme. Comparison of heme-deficient, heme-reconstituted and heme-containing forms of soluble enzyme from bovine lung

1 reference

12 December 2020

Guanylate cyclase from bovine lung. A kinetic analysis of the regulation of the purified soluble enzyme by protoporphyrin IX, heme, and nitrosyl-heme

1 reference

12 December 2020

Requirement for heme in the activation of purified guanylate cyclase by nitric oxide

1 reference

12 December 2020

Activation of soluble guanylate cyclase by NO-hemoproteins involves NO-heme exchange. Comparison of heme-containing and heme-deficient enzyme forms

1 reference

12 December 2020

The involvement of catalytic site thiol groups in the activation of soluble guanylate cyclase by sodium nitroprusside

1 reference

12 December 2020

Complexes of .NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects

1 reference

12 December 2020

Oxidation of dithiothreitol during turnover of nitric oxide reductase: evidence for generation of nitroxyl with the enzyme from Paracoccus denitrificans

1 reference

12 December 2020

Conversion of nitroxyl (HNO) to nitric oxide (NO) in biological systems: the role of physiological oxidants and relevance to the biological activity of HNO

1 reference

12 December 2020

Identification and partial purification of an endogenous inhibitor of soluble guanylyl cyclase from bovine lung

1 reference

12 December 2020

Bioassay discrimination between nitric oxide (NO.) and nitroxyl (NO-) using L-cysteine

1 reference

12 December 2020

Electron paramagnetic resonance spectral evidence for the formation of a pentacoordinate nitrosyl-heme complex on soluble guanylate cyclase

1 reference

12 December 2020

Studies of the heme coordination and ligand binding properties of soluble guanylyl cyclase (sGC): characterization of Fe(II)sGC and Fe(II)sGC(CO) by electronic absorption and magnetic circular dichroism spectroscopies and failure of CO to activate t

1 reference

12 December 2020

Spectral and ligand-binding properties of an unusual hemoprotein, the ferric form of soluble guanylate cyclase

1 reference

12 December 2020

Nitric oxide (NO), the only nitrogen monoxide redox form capable of activating soluble guanylyl cyclase

1 reference

12 December 2020

Mechanisms of inhibition of aldehyde dehydrogenase by nitroxyl, the active metabolite of the alcohol deterrent agent cyanamide

1 reference

12 December 2020

Reactions catalyzed by tetrahydrobiopterin-free nitric oxide synthase

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.014282

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531488%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

PubMed publication ID

19531488

1 reference