(Q41916835)

14 October 2017

title

Endothelial cells internalize and degrade RGD-modified proteins developed for tumor vasculature targeting (English)

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14 October 2017

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8

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14 October 2017

Astrid J Schraa

1

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14 October 2017

Robbert J Kok

2

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14 October 2017

Agnes D Berendsen

3

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14 October 2017

Henk E Moorlag

4

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14 October 2017

Erwin J Bos

5

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14 October 2017

Dirk K F Meijer

6

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14 October 2017

Lou F M H de Leij

7

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14 October 2017

language of work or name

English

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publication date

1 October 2002

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Journal of Controlled Release

14 October 2017

published in

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14 October 2017

volume

83

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14 October 2017

issue

2

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14 October 2017

page(s)

241-251

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Requirement of vascular integrin alpha v beta 3 for angiogenesis

14 October 2017

cites work

1 reference

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Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

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7 January 2021

Decreased angiogenesis and arthritic disease in rabbits treated with an alphavbeta3 antagonist.

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Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model

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Anti-cancer activity of targeted pro-apoptotic peptides

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Suppression of murine collagen-induced arthritis by targeted apoptosis of synovial neovasculature

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7 January 2021

Preparation and functional evaluation of RGD-modified proteins as alpha(v)beta(3) integrin directed therapeutics.

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7 January 2021

Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13).

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7 January 2021

Basal tissue factor expression in endothelial cell cultures is caused by contaminating smooth muscle cells. Reduction by using chymotrypsin instead of collagenase

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https://api.crossref.org/works/10.1016%2FS0168-3659%2802%2900206-7

7 January 2021

Evidence for the involvement of endothelial cell integrin alphaVbeta3 in the disruption of the tumor vasculature induced by TNF and IFN-gamma

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7 January 2021

Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity

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7 January 2021

Inhibition of angiogenesis and tumour growth by VEGF121-toxin conjugate: differential effect on proliferating endothelial cells

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7 January 2021

Tumor Infarction in Mice by Antibody-Directed Targeting of Tissue Factor to Tumor Vasculature

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7 January 2021

Phage libraries displaying cyclic peptides with different ring sizes: ligand specificities of the RGD-directed integrins

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7 January 2021

Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis

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7 January 2021

Ligation of integrin alpha5beta1 is required for internalization of vitronectin by integrin alphavbeta3.

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https://api.crossref.org/works/10.1016%2FS0168-3659%2802%2900206-7

7 January 2021

RGD peptides induce apoptosis by direct caspase-3 activation.

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7 January 2021

RGD peptides and monoclonal antibodies, antagonists of alpha(v)-integrin, enter the cells by independent endocytic pathways.

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https://api.crossref.org/works/10.1016%2FS0168-3659%2802%2900206-7

7 January 2021

Integrin transmembrane signaling and cytoskeletal control

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7 January 2021

The actin cytoskeleton is required for receptor-mediated endocytosis in mammalian cells

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7 January 2021

The role of alphav integrins during angiogenesis: insights into potential mechanisms of action and clinical development.

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7 January 2021

10.1016/S0168-3659(02)00206-7

Identifiers

DOI

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14 October 2017

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