(Q41917778)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11911834%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

title

Novel phenothiazine antimalarials: synthesis, antimalarial activity, and inhibition of the formation of beta-haematin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11911834%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

0 references

3

1 reference

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8 December 2019

author name string

Martha Kalkanidis

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11911834%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Nectarios Klonis

series ordinal

2

1 reference

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8 December 2019

Leslie W Deady

series ordinal

4

1 reference

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8 December 2019

language of work or name

English

0 references

publication date

1 March 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11911834%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

published in

Biochemical Pharmacology

1 reference

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8 December 2019

volume

63

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11911834%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

issue

5

1 reference

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8 December 2019

page(s)

833-842

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11911834%20AND%20SRC:MED&resulttype=core&format=json

Conflicts of interest: the genesis of synthetic antimalarial agents in peace and war.

8 December 2019

cites work

1 reference

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Mode of antimalarial effect of methylene blue and some of its analogues on Plasmodium falciparum in culture and their inhibition of P. vinckei petteri and P. yoelii nigeriensis in vivo

7 January 2021

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Effect of calmodulin inhibitors on viability and mitochondrial potential of Plasmodium falciparum in culture

7 January 2021

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Plasmodium falciparum: modulation by calcium antagonists of resistance to chloroquine, desethylchloroquine, quinine, and quinidine in vitro

7 January 2021

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Reversal of chloroquine resistance in Plasmodium falciparum by verapamil

7 January 2021

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Reversal of Plasmodium falciparum resistance to chloroquine in Panamanian Aotus monkeys

7 January 2021

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In vitro activities of chloroquine in combination with chlorpromazine or prochlorperazine against isolates of Plasmodium falciparum

7 January 2021

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Verapamil reversal of chloroquine resistance in the malaria parasite Plasmodium falciparum is specific for resistant parasites and independent of the weak base effect

7 January 2021

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Charged analogues of chlorpromazine as dopamine antagonists

7 January 2021

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Involvement of lipids in ferriprotoporphyrin IX polymerization in malaria

7 January 2021

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Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum

7 January 2021

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Novel bisquinoline antimalarials. Synthesis, antimalarial activity, and inhibition of haem polymerisation.

7 January 2021

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A Method for Testing for Synergy with Any Number of Agents

7 January 2021

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Synergy between two calcium channel blockers, verapamil and fantofarone (SR33557), in reversing chloroquine resistance in Plasmodium falciparum

7 January 2021

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Heme models I. solution behavior of a water soluble iron porphyrin

7 January 2021

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Hemin monomers in micellar sodium lauryl sulfate. Spectral and equilibrium study with cyanide

7 January 2021

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The quinine-haemin interaction and its relationship to antimalarial activity

7 January 2021

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Studies on haemin in dimethyl sulphoxide/water mixtures

7 January 2021

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Thermodynamic factors controlling the interaction of quinoline antimalarial drugs with ferriprotoporphyrin IX.

7 January 2021

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Characterization of chloroquine-hematin mu-oxo dimer binding by isothermal titration calorimetry

7 January 2021

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An iron-carboxylate bond links the heme units of malaria pigment

7 January 2021

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The structure of malaria pigment beta-haematin

7 January 2021

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Haem polymerization in malaria

7 January 2021

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Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites

7 January 2021

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Malarial haemozoin/beta-haematin supports haem polymerization in the absence of protein

7 January 2021

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A comparison and analysis of several ways to promote haematin (haem) polymerisation and an assessment of its initiation in vitro

7 January 2021

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Uptake of [3H]chloroquine by drug-sensitive and -resistant strains of the human malaria parasite Plasmodium falciparum

7 January 2021

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Quinoline antimalarials: mechanisms of action and resistance and prospects for new agents

7 January 2021

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Kinetic modelling of the response of Plasmodium falciparum to chloroquine and its experimental testing in vitro. Implications for mechanism of action of and resistance to the drug

7 January 2021

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High-Affinity Accumulation of Chloroquine by Mouse Erythrocytes Infected with Plasmodium berghei

7 January 2021

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Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum

7 January 2021

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Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance

7 January 2021

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The mode of action and the mechanism of resistance to antimalarial drugs

7 January 2021

1 reference

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Digestive vacuolar pH of intact intraerythrocytic P. falciparum either sensitive or resistant to chloroquine

7 January 2021

1 reference

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A comparison of the phenomenology and genetics of multidrug resistance in cancer cells and quinoline resistance in Plasmodium falciparum

7 January 2021

1 reference

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10.1016/S0006-2952(01)00840-1

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11911834%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference