(Q41920422)

14 October 2017

title

Baicalein induces autophagic cell death through AMPK/ULK1 activation and downregulation of mTORC1 complex components in human cancer cells (English)

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14 October 2017

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Pramod Aryal

1

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14 October 2017

Kijoong Kim

2

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14 October 2017

Pil-Hoon Park

3

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14 October 2017

Seongho Ham

4

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14 October 2017

Junghee Cho

5

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14 October 2017

Kyung Song

6

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14 October 2017

language of work or name

English

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publication date

11 September 2014

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14 October 2017

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14 October 2017

volume

281

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14 October 2017

issue

20

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14 October 2017

page(s)

4644-4658

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Role of autophagy in suppression of inflammation and cancer

14 October 2017

cites work

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https://api.crossref.org/works/10.1111%2FFEBS.12969

Role of autophagy in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

The Beclin 1-VPS34 complex--at the crossroads of autophagy and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

Baicalein reduces lipopolysaccharide-induced inflammation via suppressing JAK/STATs activation and ROS production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

Baicalein inhibits DMBA/TPA-induced skin tumorigenesis in mice by modulating proliferation, apoptosis, and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

Baicalein inhibits pulmonary carcinogenesis-associated inflammation and interferes with COX-2, MMP-2 and MMP-9 expressions in-vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

Baicalein inhibits oxidative stress-induced cellular damage via antioxidant effects.

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12969

Caspase-dependent apoptosis and -independent poly(ADP-ribose) polymerase cleavage induced by transforming growth factor beta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

AMPK- and p62/SQSTM1-dependent autophagy mediate resveratrol-induced cell death in chronic myelogenous leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

Autophagy is an important event for megakaryocytic differentiation of the chronic myelogenous leukemia K562 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

AMPK and mTOR coordinate the regulation of Ulk1 and mammalian autophagy initiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

Baicalein potently suppresses angiogenesis induced by vascular endothelial growth factor through the p53/Rb signaling pathway leading to G1/S cell cycle arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

Baicalein induces a dual growth arrest by modulating multiple cell cycle regulatory molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

The serine/threonine kinase ULK1 is a target of multiple phosphorylation events.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12969

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12969

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12969

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

Androgenic control of transforming growth factor-beta signaling in prostate epithelial cells through transcriptional suppression of transforming growth factor-beta receptor II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

Novel roles of Akt and mTOR in suppressing TGF-beta/ALK5-mediated Smad3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

Identification of novel autophagy regulators by a luciferase-based assay for the kinetics of autophagic flux

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

The androgen receptor represses transforming growth factor-beta signaling through interaction with Smad3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12969

21 January 2018

Identifiers

DOI

10.1111/FEBS.12969

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14 October 2017

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