(Q41923816)

14 October 2017

title

Utilization of exogenous folate in the human malaria parasite Plasmodium falciparum and its critical role in antifolate drug synergy (English)

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14 October 2017

main subject

Plasmodium falciparum

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Wang P

1

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14 October 2017

Brobey RK

2

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14 October 2017

Horii T

3

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14 October 2017

Sims PF

4

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14 October 2017

Hyde JE

5

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14 October 2017

language of work or name

English

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publication date

1 June 1999

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14 October 2017

published in

Molecular Microbiology

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14 October 2017

volume

32

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14 October 2017

issue

6

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14 October 2017

page(s)

1254-1262

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A Method for Testing for Synergy with Any Number of Agents

14 October 2017

cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

Recombinant Plasmodium falciparum dihydrofolate reductase-based in vitro screen for antifolate antimalarials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

De novo and salvage biosynthesis of pteroylpentaglutamates in the human malaria parasite, Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

In vitro activities of and mechanisms of resistance to antifol antimalarial drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

Potentiating effect of pyrimethamine and sulfadoxine against dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant Plasmodium chabaudi

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

Characterisation of the dihydrofolate reductase-thymidylate synthetase gene from human malaria parasites highly resistant to pyrimethamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

An RFLP map of the Plasmodium falciparum genome, recombination rates and favored linkage groups in a genetic cross

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

A modified in vitro sulfadoxine susceptibility assay for Plasmodium falciparum suitable for investigating Fansidar resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

The efficacy of antifolate antimalarial combinations in Africa: a predictive model based on pharmacodynamic and pharmacokinetic analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

Synergism in the folate pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

Antagonism of sulfadoxine and pyrimethamine antimalarial activity in vitro by p-aminobenzoic acid, p-aminobenzoylglutamic acid and folic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01437.X

10.1046/J.1365-2958.1999.01437.X

21 January 2018

Identifiers

DOI

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14 October 2017

1 reference