(Q41925134)

English

Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action

scientific article published on November 1998

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scholarly article

1 reference

Europe PubMed Central

14 October 2017

Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action (English)

1 reference

Europe PubMed Central

14 October 2017

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author name string

Ginsburg H

1

1 reference

Europe PubMed Central

14 October 2017

Famin O

2

1 reference

Europe PubMed Central

14 October 2017

Zhang J

3

1 reference

Europe PubMed Central

14 October 2017

Krugliak M

4

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Europe PubMed Central

14 October 2017

language of work or name

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publication date

1 November 1998

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Europe PubMed Central

14 October 2017

Biochemical Pharmacology

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Europe PubMed Central

14 October 2017

56

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Europe PubMed Central

14 October 2017

1305-1313

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Europe PubMed Central

14 October 2017

10

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Europe PubMed Central

14 October 2017

The plasmodium digestive vacuole: metabolic headquarters and choice drug target

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Hemoglobin metabolism in the malaria parasite Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Hemoglobin degradation in the human malaria pathogen Plasmodium falciparum: a catabolic pathway initiated by a specific aspartic protease

1 reference

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7 January 2021

The proteases and pathogenicity of parasitic protozoa

1 reference

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7 January 2021

Hemoglobin catabolism and iron utilization by malaria parasites

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Generation of hemoglobin peptides in the acidic digestive vacuole of Plasmodium falciparum implicates peptide transport in amino acid production.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Mechanism of hemolysis induced by ferriprotoporphyrin IX.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Hemin lyses malaria parasites

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Lysis of Plasmodium falciparum by ferriprotoporphyrin IX and a chloroquine-ferriprotoporphyrin IX complex

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Plasmodium lophurae: Composition and properties of hemozoin, the malarial pigment

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

An iron-carboxylate bond links the heme units of malaria pigment

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Kinetics of the interaction of hemin liposomes with heme binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

The effect of ferriprotoporphyrin IX and chloroquine on phospholipid monolayers and the possible implications to antimalarial activity

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Interactions of hemin, antimalarial drugs and hemin-antimalarial complexes with phospholipid monolayers

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Serum proteins as mediators of hemin efflux from red cell membranes: specificity of hemopexin

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Kinetic modelling of the response of Plasmodium falciparum to chloroquine and its experimental testing in vitro. Implications for mechanism of action of and resistance to the drug

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Amodiaquine accumulation in Plasmodium falciparum as a possible explanation for its superior antimalarial activity over chloroquine

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Malarial haemozoin/beta-haematin supports haem polymerization in the absence of protein

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

The chemical mechanism of beta-haematin formation studied by Mössbauer spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Investigations of B- and beta-hematin

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Heme polymerase: modulation by chloroquine treatment of a rodent malaria

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Quinoline anti-malarial drugs inhibit spontaneous formation of beta-haematin (malaria pigment).

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Plasmodium hemozoin formation mediated by histidine-rich proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Control of heme polymerase by chloroquine and other quinoline derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Effects of antimalarials and protease inhibitors on plasmodial hemozoin production

1 reference

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7 January 2021

Resistance of glucose-6-phosphate dehydrogenase deficiency to malaria: effects of fava bean hydroxypyrimidine glucosides on Plasmodium falciparum growth in culture and on the phagocytosis of infected cells.

1 reference

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7 January 2021

Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Hemoglobin catabolism and host-parasite heme balance in chloroquine-sensitive and chloroquine-resistant Plasmodium berghei infections.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Heme oxygenase and related indices in chloroquine-resistant and -sensitive strains of Plasmodium berghei

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Hemoglobin degradation in the malaria parasite Plasmodium falciparum: an ordered process in a unique organelle

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Heme degradation in the presence of glutathione. A proposed mechanism to account for the high levels of non-heme iron found in the membranes of hemoglobinopathic red blood cells

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Mode of action of iron (III) chelators as antimalarials. IV. Potentiation of desferal action by benzoyl and isonicotinoyl hydrazone derivatives.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Hemoglobin denaturation and iron release in acidified red blood cell lysate--a possible source of iron for intraerythrocytic malaria parasites.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Origin of reactive oxygen species in erythrocytes infected with Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Hexose-monophosphate shunt activity in intact Plasmodium falciparum-infected erythrocytes and in free parasites.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

The malaria parasite supplies glutathione to its host cell--investigation of glutathione transport and metabolism in human erythrocytes infected with Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Studies on the antimalarial mode of action of quinoline-containing drugs: time-dependence and irreversibility of drug action, and interactions with compounds that alter the function of the parasite's food vacuole

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Hemin-induced lipid membrane disorder and increased permeability: a molecular model for the mechanism of cell lysis

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Stage-Dependent Effects of Chloroquine onPlasmodium falciparumIn Vitro1

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Methods for the selective modification of glutathione metabolism and study of glutathione transport

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Plasmodium berghei: implication of intracellular glutathione and its related enzyme in chloroquine resistance in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Chloroquine resistance is not associated with drug metabolism in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Potentiation of chloroquine activity against Plasmodium falciparum by the peroxidase-hydrogen peroxide system

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Influence of quinoline-containing antimalarials in the catalase activity of ferriprotoporphyrin IX

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Comparison of proteases from chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

Molecular characterization of the glutathione peroxidase gene of the human malaria parasite Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900184-1

7 January 2021

X-ray microanalysis of Plasmodium falciparum and infected red blood cells: effects of qinghaosu and chloroquine on potassium, sodium, and phosphorus composition

1 reference

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7 January 2021

Identifiers

10.1016/S0006-2952(98)00184-1

1 reference

Europe PubMed Central

14 October 2017

1 reference

Europe PubMed Central

14 October 2017

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