(Q41940518)

14 October 2017

Stereoselective genetically-determined interaction between chronic flecainide and quinidine in patients with arrhythmias (English)

1 reference

14 October 2017

1 reference

U M Birgersdotter

1

1 reference

14 October 2017

W Wong

series ordinal

2

1 reference

14 October 2017

J Turgeon

series ordinal

3

1 reference

14 October 2017

D M Roden

series ordinal

4

1 reference

14 October 2017

language of work or name

English

0 references

publication date

1 March 1992

1 reference

British Journal of Clinical Pharmacology

14 October 2017

1 reference

14 October 2017

33

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14 October 2017

3

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14 October 2017

275-280

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A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381275

Encainide and its metabolites. Comparative effects in man on ventricular arrhythmia and electrocardiographic intervals

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381275

Electrophysiologic effects of flecainide acetate and its major metabolites in the canine heart

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381275

Partial metabolic clearances as determinants of the oral bioavailability of propranolol

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381275

Quinidine: potent inhibition of sparteine and debrisoquine oxidation in vivo.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381275

Sparteine oxidation is practically abolished in quinidine-treated patients

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381275

Classification by type of ventricular arrhythmia predicts frequency of adverse cardiac events from flecainide

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381275

Quinidine and the identification of drugs whose elimination is impaired in subjects classified as poor metabolizers of debrisoquine

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381275

Genetically-determined interaction between propafenone and low dose quinidine: role of active metabolites in modulating net drug effect

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381275

Stereoselective disposition of flecainide in relation to the sparteine/debrisoquine metaboliser phenotype

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381275

Flecainide enantiomers: disposition in human subjects and electrophysiologic actions in vitro

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381275

Effect of low dose quinidine on encainide pharmacokinetics and pharmacodynamics. Influence of genetic polymorphism.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381275

Genetically determined steady-state interaction between encainide and quinidine in patients with arrhythmias

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381275

The role of genetically determined polymorphic drug metabolism in the beta-blockade produced by propafenone

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381275

Critical evaluation of the potential error in pharmacokinetic studies of using the linear trapezoidal rule method for the calculation of the area under the plasma level--time curve

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381275

Polymorphic hydroxylation of Debrisoquine in man.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381275

The influence of the sparteine/debrisoquin phenotype on the disposition of flecainide

5 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1992.TB04035.X

Stereoselective disposition and pharmacologic activity of propafenone enantiomers

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1992.TB04035.X

Genetically determined stereoselective excretion of encainide in humans and electrophysiologic effects of its enantiomers in canine cardiac Purkinje fibers

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1992.TB04035.X

Effect of oxidative polymorphism (debrisoquine/sparteine type) on hepatic first-pass metabolism of bufuralol

21 January 2018

1 reference

12 December 2020

Co-inheritance of the polymorphic metabolism of encainide and debrisoquin

1 reference

12 December 2020

High-performance liquid chromatographic assay with fluorometric detection for flecainide and its major metabolites in urine and serum

1 reference

12 December 2020

Extensive metabolizers of debrisoquine become poor metabolizers during quinidine treatment

1 reference

12 December 2020

Quinidine reduces clearance of (+)-propranolol more than (-)-propranolol through marked reduction in 4-hydroxylation

1 reference

12 December 2020

Stereoselective determination of flecainide in human plasma by high-performance liquid chromatography with fluorescence detection

1 reference

12 December 2020

Effects of encainide and metabolites (MJ14030 and MJ9444) on canine cardiac Purkinje and ventricular fibers

1 reference

12 December 2020

Antiarrhythmic activity of the O-demethyl metabolite of encainide

1 reference

12 December 2020

Polymorphism of propafenone metabolism and disposition in man: clinical and pharmacokinetic consequences

1 reference

12 December 2020

10.1111/J.1365-2125.1992.TB04035.X

Identifiers

DOI

1 reference

14 October 2017

1 reference

14 October 2017

1 reference