(Q41949103)

English

Nerve growth factor stimulates a novel protein kinase in PC-12 cells that phosphorylates and activates mitogen-activated protein kinase kinase (MEK).

scientific article published on April 1995

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scholarly article

1 reference

Europe PubMed Central

14 October 2017

Nerve growth factor stimulates a novel protein kinase in PC-12 cells that phosphorylates and activates mitogen-activated protein kinase kinase (MEK). (English)

1 reference

Europe PubMed Central

14 October 2017

phosphorylation

0 references

author name string

Pang L

1

1 reference

Europe PubMed Central

14 October 2017

Zheng CF

2

1 reference

Europe PubMed Central

14 October 2017

Guan KL

3

1 reference

Europe PubMed Central

14 October 2017

Saltiel AR

4

1 reference

Europe PubMed Central

14 October 2017

language of work or name

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publication date

1 April 1995

1 reference

Europe PubMed Central

14 October 2017

number of pages

7

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based on heuristic

inferred from page(s)

Biochemical Journal

1 reference

Europe PubMed Central

14 October 2017

307 ( Pt 2)

1 reference

Europe PubMed Central

14 October 2017

513-519

1 reference

Europe PubMed Central

14 October 2017

Reconstitution of the Raf-1-MEK-ERK signal transduction pathway in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

5 June 2018

Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

5 June 2018

Lysophosphatidic acid stimulates mitogen-activated protein kinase activation via a G-protein-coupled pathway requiring p21ras and p74raf-1.

1 reference

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5 June 2018

A dominant-negative mutant of raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21ras.

1 reference

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5 June 2018

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

5 June 2018

A protein kinase similar to MAP kinase activator acts downstream of the raf kinase in Drosophila.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

5 June 2018

Bombesin and epidermal growth factor stimulate the mitogen-activated protein kinase through different pathways in Swiss 3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

5 June 2018

Pleiotropic signaling from receptor tyrosine kinases

1 reference

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5 June 2018

Raf-1 forms a stable complex with Mek1 and activates Mek1 by serine phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

5 June 2018

Nerve growth factor activates calcium-insensitive protein kinase C-epsilon in PC-12 rat pheochromocytoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

5 June 2018

Properties of MEKs, the kinases that phosphorylate and activate the extracellular signal-regulated kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

5 June 2018

The protein kinase mos activates MAP kinase kinase in vitro and stimulates the MAP kinase pathway in mammalian somatic cells in vivo

1 reference

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5 June 2018

Growth factor induced MEK activation is primarily mediated by an activator different from c-raf

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

5 June 2018

Insulin activates a novel adipocyte mitogen-activated protein kinase kinase kinase that shows rapid phasic kinetics and is distinct from c-Raf.

1 reference

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5 June 2018

Divergence of signaling pathways for insulin in PC-12 pheochromocytoma cells

1 reference

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Aspects of the metabolism of the epidermal growth factor receptor in A431 human epidermoid carcinoma cells

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases

1 reference

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5 June 2018

Krebs EG: Purification and characterization of a protein inhibitor of adenosine 3',5'-monophosphate-dependent protein kinases.

1 reference

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5 June 2018

Universal calibration of gel permeation chromatography and determination of molecular shape in solution.

1 reference

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5 June 2018

Identification and characterization of a mitogen-activated S6 kinase

1 reference

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5 June 2018

Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

1 reference

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5 June 2018

Regulation of casein kinase II activity by epidermal growth factor in human A-431 carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

5 June 2018

Nerve growth factor and fibroblast growth factor selectively activate a protein kinase that phosphorylates high molecular weight microtubule-associated proteins. Detection, partial purification, and characterization in PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

5 June 2018

An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control

1 reference

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5 June 2018

Nerve growth factor stimulates a protein kinase in PC-12 cells that phosphorylates microtubule-associated protein-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

5 June 2018

Identification of multiple epidermal growth factor-stimulated protein serine/threonine kinases from Swiss 3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

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ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

1 reference

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5 June 2018

Defective regulation of mitogen-activated protein kinase activity in a 3T3 cell variant mitogenically nonresponsive to tetradecanoyl phorbol acetate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

5 June 2018

Nerve growth factor induces the association of a 130-Kd phosphoprotein with its receptor in PC-12 pheochromocytoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

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Interleukin-1 represents a new modality for the activation of extracellular signal-regulated kinases/microtubule-associated protein-2 kinases

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TPA-induced activation of MAP kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

5 June 2018

Activation of the MAP kinase pathway by the protein kinase raf

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

5 June 2018

Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro

1 reference

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5 June 2018

Raf-1 activates MAP kinase-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136678

5 June 2018

Nerve growth factor stimulates the activities of the raf-1 and the mitogen-activated protein kinases via the trk protooncogene

1 reference

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5 June 2018

Purification and characterization of mitogen-activated protein kinase activator(s) from epidermal growth factor-stimulated A431 cells

1 reference

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5 June 2018

Stimulation by growth hormone of MAP kinase activity in 3T3-F442A fibroblasts

1 reference

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5 June 2018

ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

1 reference

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Mutation of the two carboxyl-terminal tyrosines in the insulin receptor results in enhanced activation of mitogen-activated protein kinase.

1 reference

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18 August 2018

Cell-free detection and characterization of a novel nerve growth factor-activated protein kinase in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7733891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of a Ca2+-inhibitable protein kinase that phosphorylates microtubule-associated protein 2 in vitro by growth factors, phorbol esters, and serum in quiescent cultured human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/7733891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for communication between nerve growth factor and protein tyrosine phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7733891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of a Microtubule-Associated Protein-2 Kinase by Insulin-Like Growth Factor-I in Bovine Chromaffin Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7733891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/7733891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth factors differentially stimulate the phosphorylation of Shc proteins and their association with Grb2 in PC-12 pheochromocytoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7733891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3070513

1 reference

Europe PubMed Central

14 October 2017

1 reference

Europe PubMed Central

14 October 2017

1 reference

Europe PubMed Central

14 October 2017

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