(Q41972387)

14 October 2017

Structure and design of broadly-neutralizing antibodies against HIV. (English)

1 reference

14 October 2017

Seong Eon Ryu

1

1 reference

PMC publication ID

3823542

14 October 2017

Wayne A Hendrickson

series ordinal

2

1 reference

14 October 2017

25 June 2012

1 reference

14 October 2017

1 reference

14 October 2017

34

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14 October 2017

3

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14 October 2017

231-237

1 reference

https://scigraph.springernature.com/pub.10.1007/s10059-012-0104-4

14 October 2017

0 references

cites work

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Extracellular HIV-1 Tat induces human beta-defensin-2 production via NF-kappaB/AP-1 dependent pathways in human B cells

5 June 2018

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Molecular mechanisms of HIV entry

5 June 2018

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Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

5 June 2018

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Increasing the potency and breadth of an HIV antibody by using structure-based rational design

5 June 2018

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Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold

5 June 2018

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Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

5 June 2018

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Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures

5 June 2018

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Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin

5 June 2018

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Comparative magnitude of cross-strain conservation of HIV variable loop neutralization epitopes

5 June 2018

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Broadly neutralizing antibodies and their significance for HIV-1 vaccines

5 June 2018

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Elicitation of structure-specific antibodies by epitope scaffolds

5 June 2018

1 reference

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Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope

5 June 2018

1 reference

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An exciting but challenging road ahead for computational enzyme design

5 June 2018

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Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

5 June 2018

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Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

5 June 2018

1 reference

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Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

5 June 2018

1 reference

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Pathogenesis of HIV infection: total CD4+ T-cell pool, immune activation, and inflammation

5 June 2018

1 reference

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

5 June 2018

1 reference

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Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers

5 June 2018

1 reference

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Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120.

5 June 2018

1 reference

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Molecular architecture of native HIV-1 gp120 trimers

5 June 2018

1 reference

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Fc receptor but not complement binding is important in antibody protection against HIV.

5 June 2018

1 reference

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Structure-activity relationships in the binding of chemically derivatized CD4 to gp120 from human immunodeficiency virus

5 June 2018

1 reference

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Broadly neutralizing anti-hepatitis B virus antibody reveals a complementarity determining region H3 lid-opening mechanism

5 June 2018

1 reference

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Isolating and engineering human antibodies using yeast surface display

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Structural definition of a conserved neutralization epitope on HIV-1 gp120

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Structure of an unliganded simian immunodeficiency virus gp120 core

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Computational design of receptor and sensor proteins with novel functions

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Timing the ancestor of the HIV-1 pandemic strains

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

The antigenic structure of the HIV gp120 envelope glycoprotein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

The CD4 antigen: physiological ligand and HIV receptor

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Identification and characterization of conserved and variable regions in the envelope gene of HTLV-III/LAV, the retrovirus of AIDS.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Crystal structure of an HIV-binding recombinant fragment of human CD4.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Discontinuous, conserved neutralization epitopes overlapping the CD4-binding region of human immunodeficiency virus type 1 gp120 envelope glycoprotein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823542

Single amino-acid changes in HIV envelope affect viral tropism and receptor binding

5 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10059-012-0104-4

10.1007/S10059-012-0104-4

21 January 2018

Identifiers

DOI

1 reference

14 October 2017

1 reference

PMC publication ID

3823542

14 October 2017

PubMed publication ID

22736269

1 reference

PMC publication ID

3823542