(Q41976376)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12358603%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

title

Factor VII mutant V154G models a zymogen-like form of factor VIIa (English)

1 reference

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13 December 2019

1 reference

4

1 reference

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13 December 2019

author name string

Raffaella Toso

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12358603%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

Francesco Bernardi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12358603%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

Theresa Tidd

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12358603%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

Rodney M Camire

5

1 reference

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13 December 2019

Giovanna Marchetti

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12358603%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

Katherine A High

7

1 reference

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13 December 2019

Eleanor S Pollak

8

1 reference

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13 December 2019

language of work or name

English

0 references

publication date

1 February 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12358603%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12358603%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

volume

369

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12358603%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

issue

Pt 3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12358603%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

page(s)

563-571

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12358603%20AND%20SRC:MED&resulttype=core&format=json

A cyclic pentapeptide derived from the second EGF-like domain of Factor VII is an inhibitor of tissue factor dependent coagulation and thrombus formation.

13 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Rational design of coagulation factor VIIa variants with substantially increased intrinsic activity.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Selection and characterization of a new class of peptide exosite inhibitors of coagulation factor VIIa

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Substitution of valine for leucine 305 in factor VIIa increases the intrinsic enzymatic activity.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Molecular mechanisms of FVII deficiency: expression of mutations clustered in the IVS7 donor splice site of factor VII gene.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Studies of the activation of factor VII bound to tissue factor

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Molecular analysis of factor VII deficiency in Italy: a frequent mutation (FVII Lazio) in a repeated intronic region.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

On the size of the active site in proteases. I. Papain

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

The reaction between bovine brain tissue factor and factors VII and X.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Factor VII binding to tissue factor in reconstituted phospholipid vesicles: induction of cooperativity by phosphatidylserine

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Characterization of a cDNA coding for human factor VII

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Activation of factor VII bound to tissue factor: a key early step in the tissue factor pathway of blood coagulation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Nucleotide sequence of the gene coding for human factor VII, a vitamin K-dependent protein participating in blood coagulation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Proteolytic activation of human factors IX and X by recombinant human factor VIIa: effects of calcium, phospholipids, and tissue factor

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Initiation of the extrinsic pathway of blood coagulation: evidence for the tissue factor dependent autoactivation of human coagulation factor VII.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Quantitative evaluation of solution equilibrium binding interactions by affinity partitioning: application to specific and nonspecific protein-heparin interactions.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Deletion of the membrane anchoring region of tissue factor abolishes autoactivation of factor VII but not cofactor function. Analysis of a mutant with a selective deficiency in activity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding. II. The binding of the pancreatic trypsin inhibitor and of isoleucine-valine and of sequentially related peptides to trypsinogen and to p-guanidinobenzoate-tryp

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

A frequent human coagulation Factor VII mutation (A294V, c152) in loop 140s affects the interaction with activators, tissue factor and substrates.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Factor VIIa modified in the 170 loop shows enhanced catalytic activity but does not change the zymogen-like property

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Residue Met(156) contributes to the labile enzyme conformation of coagulation factor VIIa

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Kinetics of human factor VII activation.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223097

Role of residue Phe225 in the cofactor-mediated, allosteric regulation of the serine protease coagulation factor VIIa

18 August 2018

1 reference

12 December 2020

Twenty two novel mutations of the factor VII gene in factor VII deficiency

1 reference

12 December 2020

The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding. The refined crystal structures of the bovine trypsinogen-pancreatic trypsin inhibitor complex and of its ternary complex with Ile-Val at 1.9 A resolution

1 reference

12 December 2020

Solution composition dependent variation in extinction coefficients for p-nitroaniline

1 reference

12 December 2020

The interaction of bovine factor V and factor V-derived peptides with phospholipid vesicles

1 reference

12 December 2020

Phospholipid-independent and -dependent interactions required for tissue factor receptor and cofactor function

1 reference

12 December 2020

The interaction of human factor VIIa with tissue factor

1 reference

12 December 2020

Quantitation of activated factor VII levels in plasma using a tissue factor mutant selectively deficient in promoting factor VII activation

1 reference

12 December 2020

Factor VII autoactivation proceeds via interaction of distinct protease-cofactor and zymogen-cofactor complexes. Implications of a two-dimensional enzyme kinetic mechanism

1 reference

12 December 2020

Extrinsic pathway proteolytic activity

1 reference

12 December 2020

Severe factor VII deficiency caused by mutations abolishing the cleavage site for activation and altering binding to tissue factor

1 reference

12 December 2020

Identification of regions of bovine factor VII essential for binding to tissue factor

1 reference

12 December 2020

Molecular mechanism of tissue factor-mediated acceleration of factor VIIa activity

1 reference

12 December 2020

Active site modification of factor VIIa affects interactions of the protease domain with tissue factor

1 reference

12 December 2020

Conformation of factor VIIa stabilized by a labile disulfide bond (Cys-310-Cys-329) in the protease domain is essential for interaction with tissue factor

1 reference

12 December 2020

Influence of cofactor binding and active site occupancy on the conformation of the macromolecular substrate exosite of factor VIIa

1 reference

12 December 2020

Regions remote from the site of cleavage determine macromolecular substrate recognition by the prothrombinase complex

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ20020888

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12358603%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12358603%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

PubMed publication ID

12358603

1 reference