(Q41993255)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18075491%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

Aging exacerbates depressive-like behavior in mice in response to activation of the peripheral innate immune system (English)

1 reference

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29 December 2019

10

1 reference

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29 December 2019

Nathalie Castanon

7

1 reference

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29 December 2019

Keith W. Kelley

8

1 reference

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29 December 2019

Robert Dantzer

9

1 reference

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29 December 2019

author name string

Jonathan P Godbout

1

1 reference

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29 December 2019

Maïté Moreau

2

1 reference

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29 December 2019

Jacques Lestage

3

1 reference

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29 December 2019

Jing Chen

4

1 reference

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29 December 2019

Nathan L Sparkman

5

1 reference

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29 December 2019

Jason O'Connor

6

1 reference

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29 December 2019

language of work or name

English

0 references

publication date

12 December 2007

1 reference

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29 December 2019

published in

Neuropsychopharmacology

1 reference

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29 December 2019

volume

33

1 reference

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29 December 2019

issue

10

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29 December 2019

page(s)

2341-2351

1 reference

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https://scigraph.springernature.com/pub.10.1038/sj.npp.1301649

29 December 2019

exact match

0 references

cites work

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice.

1 reference

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Exaggerated sickness behavior and brain proinflammatory cytokine expression in aged mice in response to intracerebroventricular lipopolysaccharide

5 June 2018

1 reference

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Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior.

5 June 2018

1 reference

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Systemic infections and inflammation affect chronic neurodegeneration

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Age and neuroinflammation: a lifetime of psychoneuroimmune consequences

5 June 2018

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Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application

5 June 2018

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Cytokines sing the blues: inflammation and the pathogenesis of depression

5 June 2018

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Effects of interleukin-1 and endotoxin in the forced swim and tail suspension tests in mice

5 June 2018

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Stress, depression, and anhedonia: caveats concerning animal models

5 June 2018

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mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging

5 June 2018

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Cytokines as mediators of depression: what can we learn from animal studies?

5 June 2018

1 reference

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Stress-induced immune dysfunction: implications for health

5 June 2018

1 reference

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Cytokines and major depression

5 June 2018

1 reference

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Expression of indoleamine 2,3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons

5 June 2018

1 reference

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The role of indoleamine 2,3-dioxygenase (IDO) in the pathophysiology of interferon-alpha-induced depression

5 June 2018

1 reference

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Interferon-alpha-induced changes in tryptophan metabolism. relationship to depression and paroxetine treatment

5 June 2018

1 reference

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Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene

5 June 2018

1 reference

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Involvement of serotonin in depression: evidence from postmortem and imaging studies of serotonin receptors and the serotonin transporter

5 June 2018

1 reference

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Chronic stress and age-related increases in the proinflammatory cytokine IL-6

5 June 2018

1 reference

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Immune activation and degradation of tryptophan in coronary heart disease

5 June 2018

1 reference

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Cytokines and depression: the need for a new paradigm

5 June 2018

1 reference

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Low levels of circulating inflammatory cytokines--do they affect human brain functions?

5 June 2018

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

5 June 2018

1 reference

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Serotonergic gene expression and depression: implications for developing novel antidepressants.

5 June 2018

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Animal models of depression: utility for transgenic research

5 June 2018

1 reference

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Oxidative stress as a mechanism for quinolinic acid-induced hippocampal damage: protection by melatonin and deprenyl

5 June 2018

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Epidemiology and diagnosis of depression in late life

5 June 2018

1 reference

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Gene expression profile of aging and its retardation by caloric restriction

5 June 2018

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Association of interleukin-6 and other biologic variables with depression in older people living in the community

5 June 2018

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The role of interleukin-6 in the activation of the hypothalamo-pituitary-adrenocortical axis and brain indoleamines by endotoxin and interleukin-1 beta.

5 June 2018

1 reference

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Microglial expression of MHC class II increases in normal aging of nonhuman primates.

5 June 2018

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Altered antigen expression of microglia in the aged rodent CNS.

5 June 2018

1 reference

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Endotoxin-induced activation of cerebral catecholamine and serotonin metabolism: comparison with interleukin-1

5 June 2018

1 reference

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IL-6 knockout mice exhibit resistance to stress-induced development of depression-like behaviors.

5 June 2018

1 reference

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Role of IL-1 in poststroke depressive-like behavior in mice.

18 August 2018

1 reference

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Improved psychomotor performance in aged mice fed diet high in antioxidants is associated with reduced ex vivo brain interleukin-6 production

18 August 2018

1 reference

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Bacille Calmette-Guérin inoculation induces chronic activation of peripheral and brain indoleamine 2,3-dioxygenase in mice.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Exaggerated neuroinflammation and sickness behavior in aged mice following activation of the peripheral innate immune system.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Peripheral infection and aging interact to impair hippocampal memory consolidation.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

alpha-Tocopherol reduces lipopolysaccharide-induced peroxide radical formation and interleukin-6 secretion in primary murine microglia and in brain.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Alpha-tocopherol attenuates lipopolysaccharide-induced sickness behavior in mice.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Mild depressive symptoms are associated with amplified and prolonged inflammatory responses after influenza virus vaccination in older adults

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Inflammatory markers and depressed mood in older persons: results from the Health, Aging and Body Composition study

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

The enzyme indoleamine 2,3-dioxygenase is induced in the mouse brain in response to peripheral administration of lipopolysaccharide and superantigen.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Association between decreased serum tryptophan concentrations and depressive symptoms in cancer patients undergoing cytokine therapy.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Synthesis and release of neurotoxic kynurenine metabolites by human monocyte-derived macrophages

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Association between immune activation and early depressive symptoms in cancer patients treated with interleukin-2-based therapy.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Treatment with interferon-alpha (IFN alpha) of hepatitis C patients induces lower serum dipeptidyl peptidase IV activity, which is related to IFN alpha-induced depressive and anxiety symptoms and immune activation.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Peripheral interleukin-6 administration increases extracellular concentrations of serotonin and the evoked release of serotonin in the rat striatum

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Cerebrospinal cytokine levels in patients with acute depression.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Minor and major depression and the risk of death in older persons

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Increased interleukin-6 expression by microglia from brain of aged mice

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Mouse interleukin-6 stimulates the HPA axis and increases brain tryptophan and serotonin metabolism.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

3-Hydroxykynurenine, an endogenous oxidative stress generator, causes neuronal cell death with apoptotic features and region selectivity.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Species heterogeneity between gerbils and rats: quinolinate production by microglia and astrocytes and accumulations in response to ischemic brain injury and systemic immune activation.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Activation of microglia in the brains of humans with heart disease and hypercholesterolemic rabbits.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

A mechanism for increased quinolinic acid formation following acute systemic immune stimulation

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Increase in Interleukin-1β in Late-Life Depression

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907915

Gene-expression profile of the ageing brain in mice

2 December 2018

1 reference

12 December 2020

Kynurenine pathway enzymes in brain: responses to ischemic brain injury versus systemic immune activation

1 reference

12 December 2020

Interleukin-6 serum levels in depressed patients before and after treatment with fluoxetine

1 reference

12 December 2020

Endocrine and cytokine correlates of major depression and dysthymia with typical or atypical features

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.NPP.1301649

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18075491%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18075491%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

PubMed publication ID

18075491

1 reference