(Q41998153)

English

Conditions that result in the mobilization and influx of Ca2+ into rat hepatocytes induce the rapid loss of 3-hydroxy-3-methylglutaryl-CoA reductase activity that is not reversed by phosphatase treatment

scientific article published on July 1990

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scholarly article

1 reference

Europe PubMed Central

15 October 2017

Conditions that result in the mobilization and influx of Ca2+ into rat hepatocytes induce the rapid loss of 3-hydroxy-3-methylglutaryl-CoA reductase activity that is not reversed by phosphatase treatment (English)

1 reference

Europe PubMed Central

15 October 2017

author name string

Zammit VA

1

1 reference

Europe PubMed Central

15 October 2017

Caldwell AM

2

1 reference

Europe PubMed Central

15 October 2017

language of work or name

0 references

publication date

1 July 1990

1 reference

Europe PubMed Central

15 October 2017

Biochemical Journal

1 reference

Europe PubMed Central

15 October 2017

269

1 reference

Europe PubMed Central

15 October 2017

373-379

1 reference

Europe PubMed Central

15 October 2017

2

1 reference

Europe PubMed Central

15 October 2017

Protein measurement with the Folin phenol reagent

1 reference

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5 June 2018

Regulation of synthesis and degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase by low density lipoprotein and 25-hydroxycholesterol in UT-1 cells

1 reference

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5 June 2018

A cold-clamping technique for the rapid sampling of rat liver for studies on enzymes in separate cell fractions. Suitability for the study of enzymes regulated by reversible phosphorylation-dephosphorylation

1 reference

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5 June 2018

The protein phosphatases involved in cellular regulation. 6. Measurement of type-1 and type-2 protein phosphatases in extracts of mammalian tissues; an assessment of their physiological roles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Regulation of liver hydroxymethylglutaryl-CoA reductase by a bicyclic phosphorylation system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase mRNA levels in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Isolation and purification of 3-hydroxy-3-methylglutaryl-coenzyme A by ion-exchange chromatography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Diurnal changes in the fraction of 3-hydroxy-3-methylglutaryl-CoA reductase in the active form in rat liver microsomal fractions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Effects of diabetes on the expressed and total activities of 3-hydroxy-3-methylglutaryl-CoA reductase in rat liver in vivo. Reversal by insulin treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Regulation of hepatic HMG-CoA reductase in vivo by reversible phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Role of reversible phosphorylation in mediating changes in the activity of hepatic 3-hydroxy-3-methylglutaryl-CoA reductase during pregnancy and lactation in the rat.

1 reference

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5 June 2018

Modulation of the enzymic activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase by multiple kinase systems involving reversible phosphorylation: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Regulation of hepatic glycogen phosphorylase and glycogen synthase by calcium and diacylglycerol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Low-density lipoprotein: an old substance with a new function?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Second messengers and the regulation of Ca2+ fluxes by Ca2+-mobilizing agonists in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Synergistic stimulation of Ca2+ uptake by glucagon and Ca2+-mobilizing hormones in the perfused rat liver. A role for mitochondria in long-term Ca2+ homoeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Effect of cyclic AMP-dependent hormones and Ca2+-mobilizing hormones on the Ca2+ influx and polyphosphoinositide metabolism in isolated rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

cAMP-dependent protein kinase activation lowers hepatocyte cAMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Acute effects of starvation and treatment of rats with anti-insulin serum, glucagon and catecholamines on the state of phosphorylation of hepatic 3-hydroxy-3-methylglutaryl-CoA reductase in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Low density lipoprotein causes general cellular activation with increased phosphatidylinositol turnover and lipoprotein catabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Inositol trisphosphate and diacylglycerol as intracellular second messengers in liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Effect of diabetes on hormone-stimulated and basal hepatocyte calcium metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Phosphorylation of native 97-kDa 3-hydroxy-3-methylglutaryl-coenzyme A reductase from rat liver. Impact on activity and degradation of the enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Glucagon desensitization of adenylate cyclase and stimulation of inositol phospholipid metabolism does not involve the inhibitory guanine nucleotide regulatory protein Gi, which is inactivated upon challenge of hepatocytes with glucagon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Regulation of HMG-CoA reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Modulation of hydroxymethylglutaryl-CoA reductase activity, reductase kinase activity, and cholesterol synthesis in rat hepatocytes in response to insulin and glucagon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

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Rapid Hormonal Control of Hepatic Catabolism in Health and Disease

1 reference

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Reduction of plasma triglyceride concentration by acute stress in man

1 reference

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5 June 2018

Chapter 4 Preparation of Isolated Rat Liver Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Studies on the alpha-adrenergic activation of hepatic glucose output. I. Studies on the alpha-adrenergic activation of phosphorylase and gluconeogenesis and inactivation of glycogen synthase in isolated rat liver parenchymal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

5 June 2018

Phosphorylation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131587

18 August 2018

Studies on the hepatic calcium-mobilizing activity of aluminum fluoride and glucagon. Modulation by cAMP and phorbol myristate acetate.

1 reference

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18 August 2018

Mevalonolactone inhibits the rate of synthesis and enhances the rate of degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2167066

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the role of phosphorylase kinase, protein kinase C, and other Ca2+-sensitive protein kinases in the response of hepatocytes to angiotensin II and vasopressin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2167066

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in a somatic cell mutant auxotrophic for mevalonate

1 reference

https://pubmed.ncbi.nlm.nih.gov/2167066

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of microsomal HMG CoA reductase increases susceptibility to proteolytic degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2167066

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of 1,2-diacylglycerol accumulation in hepatocytes by vasopressin, epinephrine, and angiotensin II

1 reference

https://pubmed.ncbi.nlm.nih.gov/2167066

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of HMG-CoA reductase induced by mevalonate accelerates its rate of degradation in isolated rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2167066

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of glucagon on the synthesis and degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2167066

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two glucagon transducing systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/2167066

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycogen phosphorylase: a noninvasive indicator of cytoplasmic calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/2167066

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2167066

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid activation of human platelets by low concentrations of low-density lipoprotein via phosphatidylinositol cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/2167066

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based on heuristic

inferred from PubMed ID database lookup

Vasopressin in rats with genetic and streptozocin-induced diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2167066

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based on heuristic

inferred from PubMed ID database lookup

Vasoconstriction: a novel activity for low density lipoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/2167066

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ2690373

1 reference

Europe PubMed Central

15 October 2017

1 reference

Europe PubMed Central

15 October 2017

1 reference

Europe PubMed Central

15 October 2017

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