(Q42006448)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Absence of caspase-3 protects pancreatic {beta}-cells from c-Myc-induced apoptosis without leading to tumor formation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

11

1 reference

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21 January 2020

Razq Hakem

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Ming-Sound Tsao

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Minna Woo

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

author name string

Anna Radziszewska

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Stephanie A Schroer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Diana Choi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Panteha Tajmir

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Nikolina Radulovich

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

James C Ho

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Linyuan Wang

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Nicole Liadis

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Gerard I Evan

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

language of work or name

English

0 references

publication date

12 February 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

21 January 2020

published in

1 reference

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21 January 2020

volume

284

1 reference

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21 January 2020

issue

16

1 reference

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21 January 2020

page(s)

10947-10956

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

21 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2667780/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Critical requirement for cell cycle inhibitors in sustaining nonproliferative states.

5 June 2018

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Nucleophosmin suppresses oncogene-induced apoptosis and senescence and enhances oncogenic cooperation in cells with genomic instability

5 June 2018

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The Myc-dependent angiogenic switch in tumors is mediated by interleukin 1beta

5 June 2018

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The c-Myc target gene network

5 June 2018

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Exposure to chronic high glucose induces beta-cell apoptosis through decreased interaction of glucokinase with mitochondria: downregulation of glucokinase in pancreatic beta-cells

5 June 2018

1 reference

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Caspase-3-dependent beta-cell apoptosis in the initiation of autoimmune diabetes mellitus.

5 June 2018

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Muscle-specific Pten deletion protects against insulin resistance and diabetes

5 June 2018

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High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism

5 June 2018

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Prolonged culture in low glucose induces apoptosis of rat pancreatic beta-cells through induction of c-myc.

5 June 2018

1 reference

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Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity

5 June 2018

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5 June 2018

The many faces of c-MYC.

1 reference

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Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

5 June 2018

1 reference

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A large scale genetic analysis of c-Myc-regulated gene expression patterns

5 June 2018

1 reference

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Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

5 June 2018

1 reference

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Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes

5 June 2018

1 reference

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Ex vivo whole-embryo culture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heart

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667780

c-Myc augments the apoptotic activity of cytosolic death receptor signaling proteins by engaging the mitochondrial apoptotic pathway

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667780

Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667780

High glucose stimulates early response gene c-Myc expression in rat pancreatic beta cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667780

Executionary pathway for apoptosis: lessons from mutant mice

5 June 2018

1 reference

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Action of Myc in vivo - proliferation and apoptosis

5 June 2018

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c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

5 June 2018

1 reference

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Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

5 June 2018

1 reference

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Emerging roles of caspase-3 in apoptosis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667780

Essential role of caspase-3 in apoptosis of mouse beta-cells transfected with human Fas.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667780

c-Myc target genes involved in cell growth, apoptosis, and metabolism

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667780

5 June 2018

Caspases: enemies within

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667780

Differential requirement for caspase 9 in apoptotic pathways in vivo.

5 June 2018

1 reference

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Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade

5 June 2018

1 reference

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Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

5 June 2018

1 reference

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

5 June 2018

1 reference

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Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

5 June 2018

1 reference

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A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

5 June 2018

1 reference

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

5 June 2018

1 reference

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Myc induces cyclin D1 expression in the absence of de novo protein synthesis and links mitogen-stimulated signal transduction to the cell cycle.

5 June 2018

1 reference

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Biological activities of v-myc and rearranged c-myc oncogenes in rat fibroblast cells in culture

5 June 2018

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Onset of cell-specific gene expression in the developing mouse pancreas

5 June 2018

1 reference

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Bcl-xL gain of function and p19 ARF loss of function cooperate oncogenically with Myc in vivo by distinct mechanisms

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667780

Reversible kinetic analysis of Myc targets in vivo provides novel insights into Myc-mediated tumorigenesis.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667780

Specific requirement for Bax, not Bak, in Myc-induced apoptosis and tumor suppression in vivo

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667780

Type 2 diabetes-a matter of beta-cell life and death?

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667780

Overexpression of c-Myc in beta-cells of transgenic mice causes proliferation and apoptosis, downregulation of insulin gene expression, and diabetes

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667780

Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667780

Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667780

Substrate specificities of caspase family proteases

17 August 2018

1 reference

12 December 2020

Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes

1 reference

12 December 2020

Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion

1 reference

12 December 2020

In vivo evidence that caspase-3 is required for Fas-mediated apoptosis of hepatocytes

1 reference

12 December 2020

Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M806960200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213729%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference