(Q42012571)

English

Development of targeted therapy for a broad spectrum of cancers (pancreatic cancer, ovarian cancer, glioblastoma and HCC) mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22993648%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Development of targeted therapy for a broad spectrum of cancers (pancreatic cancer, ovarian cancer, glioblastoma and HCC) mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22993648%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

based on heuristic

inferred from title

pancreatic cancer

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Doron Amit

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22993648%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Abraham Hochberg

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22993648%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

publication date

22 August 2012

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22993648%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

International Journal of Clinical and Experimental Medicine

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22993648%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22993648%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22993648%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

296-305

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22993648%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

Insulin-like growth factor 2 expression modulates Taxol resistance and is a candidate biomarker for reduced disease-free survival in ovarian cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

The oncofetal H19 RNA connection: hypoxia, p53 and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

The H19 non-coding RNA is essential for human tumor growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

Insulin-like growth factor ligands, receptors, and binding proteins in cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

Inhibition of tumor growth by DT-A expressed under the control of IGF2 P3 and P4 promoter sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

The role of insulin-like growth factor 2 and its receptors in human tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

A methylated oligonucleotide inhibits IGF2 expression and enhances survival in a model of hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

The imprinted H19 gene is a marker of early recurrence in human bladder carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

The non-coding RNAs as riboregulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

Role of the insulin-like growth factor family in cancer development and progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

A quantitative reverse transcription and polymerase chain reaction assay for human IGF-II allows direct comparison of IGF-II mRNA levels in cancerous breast, bladder, and prostate tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

Promoter usage for insulin-like growth factor-II in cancerous and benign human breast, prostate, and bladder tissues, and confirmation of a 10th exon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

The expression of the H19 gene and its function in human bladder carcinoma cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

Imprinted H19 oncofetal RNA is a candidate tumour marker for hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

Insulin-like growth factor 2 and overgrowth: molecular biology and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

The product of the imprinted H19 gene is an oncofetal RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

Normal development and neoplasia: the imprinting connection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

Human imprinted genes as oncodevelopmental markers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

The imprinted H19 gene as a tumor marker in bladder carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

An enhancer deletion affects both H19 and Igf2 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

Differential expression of the human insulin-like growth factor II gene. Characterization of the IGF-II mRNAs and an mRNA encoding a putative IGF-II-associated protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

Identification and initial characterization of a fourth leader exon and promoter of the human IGF-II gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

5 June 2018

Promoter-specific transcription of insulin-like growth factor-II in epithelial ovarian cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

17 August 2018

Monoallelic up-regulation of the imprinted H19 gene in airway epithelium of phenotypically normal cigarette smokers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

17 August 2018

Transcriptional regulation and biological significance of the insulin like growth factor II gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

17 August 2018

Expression of insulin-like growth factor (IGF)-II in human prostate, breast, bladder, and paraganglioma tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

17 August 2018

Differential expression of the human, mouse and rat IGF-II genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

17 August 2018

Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

17 August 2018

Relaxation of Imprinting of Human Insulin-like Growth Factor II Gene,IGF2,in Sporadic Breast Carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443897

2 December 2018

Promoter-specific IGF2 imprinting status and its plasticity during human liver development

1 reference

https://pubmed.ncbi.nlm.nih.gov/22993648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relaxation of imprinting in trophoblastic disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22993648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor-II as a prognostic factor in pulmonary adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22993648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of insulin-like growth factor 2 in hepatocellular carcinoma is primarily regulated at the transcriptional level

1 reference

https://pubmed.ncbi.nlm.nih.gov/22993648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of insulin-like growth factor-2 can predict the prognosis of human colorectal cancer patients: correlation with tumor progression, proliferative activity and survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/22993648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible paracrine mechanism of insulin-like growth factor-2 in the development of liver metastases from colorectal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22993648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Egr-1 mediates transcriptional activation of IGF-II gene in response to hypoxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22993648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic overexpression of IGF-II induces spontaneous lung tumors: a model for human lung adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22993648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent IGF2/H19 domain epigenetic alterations and elevated IGF2 expression in epithelial ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22993648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parental genomic imprinting of the human IGF2 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/22993648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2

1 reference

https://pubmed.ncbi.nlm.nih.gov/22993648

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22993648%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22993648%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q42012571&oldid=1560824714"