(Q42014456)

English

Quantitative confocal spectral imaging analysis of mitoxantrone within living K562 cells: intracellular accumulation and distribution of monomers, aggregates, naphtoquinoxaline metabolite, and drug-target complexes

scientific article published on December 1997

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scholarly article

1 reference

Europe PubMed Central

15 October 2017

Quantitative confocal spectral imaging analysis of mitoxantrone within living K562 cells: intracellular accumulation and distribution of monomers, aggregates, naphtoquinoxaline metabolite, and drug-target complexes (English)

1 reference

Europe PubMed Central

15 October 2017

author name string

Feofanov A

1

1 reference

Europe PubMed Central

15 October 2017

Sharonov S

2

1 reference

Europe PubMed Central

15 October 2017

Fleury F

3

1 reference

Europe PubMed Central

15 October 2017

Kudelina I

4

1 reference

Europe PubMed Central

15 October 2017

Nabiev I

5

1 reference

Europe PubMed Central

15 October 2017

language of work or name

0 references

publication date

1 December 1997

1 reference

Europe PubMed Central

15 October 2017

Biophysical Journal

1 reference

Europe PubMed Central

15 October 2017

73

1 reference

Europe PubMed Central

15 October 2017

6

1 reference

Europe PubMed Central

15 October 2017

3328-3336

1 reference

Europe PubMed Central

15 October 2017

Localization and molecular interactions of mitoxantrone within living K562 cells as probed by confocal spectral imaging analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

DNA topoisomerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

Discrete localization of different DNA topoisomerases in HeLa and K562 cell nuclei and subnuclear fractions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

When good enzymes go bad: conversion of topoisomerase II to a cellular toxin by antineoplastic drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

Cytochrome P-450-induced cytotoxicity of mitoxantrone by formation of electrophilic intermediates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

High-dose mitoxantrone induces programmed cell death or apoptosis in human myeloid leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

Clinical pharmacology of mitoxantrone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

Relationship between the pharmacological activity of antitumor drugs Ametantrone and mitoxantrone (Novatrone) and their ability to condense nucleic acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

Development of resistance and characteristics of a human colon carcinoma subline resistant to mitoxantrone in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

Enzymatic oxidative activation and transformation of the antitumor agent mitoxantrone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

Evidence for human liver mediated free-radical formation by doxorubicin and mitozantrone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

Persistent intracellular binding of mitoxantrone in a human colon carcinoma cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

Topoisomerase-targeting antitumor drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

Pharmacokinetics and metabolism of mitoxantrone. A review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

Mitoxantrone-DNA binding and the induction of topoisomerase II associated DNA damage in multi-drug resistant small cell lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

Long-term inhibition of DNA synthesis and the persistence of trapped topoisomerase II complexes in determining the toxicity of the antitumor DNA intercalators mAMSA and mitoxantrone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

Inhibition of microtubule assembly is a possible mechanism of action of mitoxantrone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

Mitoxantrone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the chemotherapy of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

Subcellular distribution of the anticancer drug mitoxantrone in human and drug-resistant murine cells analyzed by flow cytometry and confocal microscopy and its relationship to the induction of DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181234

5 June 2018

[Luminescence of porphyrins in Candida yeasts grown on hydrocarbons]

1 reference

https://pubmed.ncbi.nlm.nih.gov/9414243

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of a new antitumor agent, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]-ethyl]amino]-9,10-anthracenedione, with nucleic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/9414243

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of antitumor agents ametantrone∗∗Trade name for the salt of 1,4-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione (Fig. 1, I). Abbreviations: HAQ, ANT; NSC-287513. and mitoxantrone (novatrone)††Trade name for the sa

1 reference

https://pubmed.ncbi.nlm.nih.gov/9414243

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the metabolism of mitozantrone by microsomal glutathione transferases and 3-methylcholanthrene-inducible glucuronosyl transferases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9414243

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Horseradish peroxidase-catalyzed oxidation of mitoxantrone: spectrophotometric and electron paramagnetic resonance studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9414243

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized multicenter trial of cytosine arabinoside with mitoxantrone or daunorubicin in previously untreated adult patients with acute nonlymphocytic leukemia (ANLL). Lederle Cooperative Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/9414243

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for oxidative activation of mitoxantrone in human, pig, and rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/9414243

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/S0006-3495(97)78357-7

1 reference

Europe PubMed Central

15 October 2017

1 reference

Europe PubMed Central

15 October 2017

1 reference

Europe PubMed Central

15 October 2017

ResearchGate publication ID

0 references

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