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Nrg1 is an injury-induced cardiomyocyte mitogen for the endogenous heart regeneration program in zebrafish
scientific article published on April 2015
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Europe PubMed Central
PMC publication ID
4379493
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830562%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
title
Nrg1 is an injury-induced cardiomyocyte mitogen for the endogenous heart regeneration program in zebrafish
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4379493
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830562%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
main subject
Danio rerio
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author
Kenneth D Poss
series ordinal
4
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Europe PubMed Central
PMC publication ID
4379493
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830562%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
author name string
Matthew Gemberling
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1
1 reference
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Europe PubMed Central
PMC publication ID
4379493
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830562%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
Ravi Karra
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2
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Europe PubMed Central
PMC publication ID
4379493
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830562%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
Amy L Dickson
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3
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PMC publication ID
4379493
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830562%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
language of work or name
English
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publication date
1 April 2015
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Europe PubMed Central
PMC publication ID
4379493
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830562%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
published in
eLife
1 reference
stated in
Europe PubMed Central
PMC publication ID
4379493
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830562%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
volume
4
1 reference
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Europe PubMed Central
PMC publication ID
4379493
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830562%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4379493/fullTextXML
based on heuristic
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cites work
Recombinant neuregulin 1 does not activate cardiomyocyte DNA synthesis in normal or infarcted adult mice.
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PubMed Central
reference URL
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Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts.
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Cell therapy for cardiac repair--lessons from clinical trials.
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5 June 2018
Signalling between microvascular endothelium and cardiomyocytes through neuregulin
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5 June 2018
Hippo signaling impedes adult heart regeneration.
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5 June 2018
Fibronectin is deposited by injury-activated epicardial cells and is necessary for zebrafish heart regeneration
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reference URL
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5 June 2018
The zebrafish as a model for complex tissue regeneration
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5 June 2018
Hippo pathway effector Yap promotes cardiac regeneration
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PubMed Central
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5 June 2018
Translational profiling of cardiomyocytes identifies an early Jak1/Stat3 injury response required for zebrafish heart regeneration
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
An injury-responsive gata4 program shapes the zebrafish cardiac ventricle
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
Functional screening identifies miRNAs inducing cardiac regeneration.
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PubMed Central
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Mammalian heart renewal by pre-existing cardiomyocytes
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5 June 2018
Hypoxia induces myocardial regeneration in zebrafish
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PubMed Central
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5 June 2018
Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts
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PubMed Central
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5 June 2018
Heart repair by reprogramming non-myocytes with cardiac transcription factors
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PubMed Central
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5 June 2018
The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
Clonally dominant cardiomyocytes direct heart morphogenesis
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PubMed Central
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5 June 2018
In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes
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PubMed Central
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5 June 2018
Regulation of zebrafish heart regeneration by miR-133
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PubMed Central
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5 June 2018
Endothelial-derived neuregulin is an important mediator of ischaemia-induced angiogenesis and arteriogenesis
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PubMed Central
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RNAscope: a novel in situ RNA analysis platform for formalin-fixed, paraffin-embedded tissues
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Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes
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5 June 2018
The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regeneration
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
Heart regeneration
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
Transient regenerative potential of the neonatal mouse heart
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A dual role for ErbB2 signaling in cardiac trabeculation
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PubMed Central
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5 June 2018
Parenteral administration of recombinant human neuregulin-1 to patients with stable chronic heart failure produces favourable acute and chronic haemodynamic responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
T-box binding sites are required for activity of a cardiac GATA-4 enhancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
Heart regeneration in zebrafish
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
Requirement for neuregulin receptor erbB2 in neural and cardiac development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
Multiple essential functions of neuregulin in development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
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5 June 2018
Isolation and in vitro culture of primary cardiomyocytes from adult zebrafish hearts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
retrieved
17 August 2018
Neuregulin induces CTGF expression in hypertrophic scarring fibroblasts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
retrieved
17 August 2018
Regulated addition of new myocardial and epicardial cells fosters homeostatic cardiac growth and maintenance in adult zebrafish
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
retrieved
17 August 2018
A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
retrieved
17 August 2018
Neuregulin-1alpha and beta isoform expression in cardiac microvascular endothelial cells and function in cardiac myocytes in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
retrieved
17 August 2018
Targeted expression of cyclin D2 results in cardiomyocyte DNA synthesis and infarct regression in transgenic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
retrieved
17 August 2018
Isoform-specific expression and function of neuregulin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379493
retrieved
17 August 2018
The regenerative capacity of the zebrafish heart is dependent on TGF signaling
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25830562
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A role for Schwann cell-derived neuregulin-1 in remyelination
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25830562
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.7554/ELIFE.05871
1 reference
stated in
Europe PubMed Central
PMC publication ID
4379493
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830562%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
PMC publication ID
4379493
1 reference
stated in
Europe PubMed Central
PMC publication ID
4379493
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830562%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
PubMed publication ID
25830562
1 reference
stated in
Europe PubMed Central
PMC publication ID
4379493
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830562%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
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