(Q42029480)

English

[Arg6,D-Trp7,9,NmePhe8]-substance P (6-11) activates JNK and induces apoptosis in small cell lung cancer cells via an oxidant-dependent mechanism

scientific article published on June 1999

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

[Arg6,D-Trp7,9,NmePhe8]-substance P (6-11) activates JNK and induces apoptosis in small cell lung cancer cells via an oxidant-dependent mechanism (English)

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

0 references

author name string

MacKinnon AC

1

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Armstrong RA

2

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Waters CM

3

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Cummings J

4

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Smyth JF

5

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Haslett C

6

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Sethi T

7

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

language of work or name

0 references

publication date

1 June 1999

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

British Journal of Cancer

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

80

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

7

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

1026-1034

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

https://scigraph.springernature.com/pub.10.1038/sj.bjc.6690458

0 references

Role of tyrosine kinase activity of epidermal growth factor receptor in the lysophosphatidic acid-stimulated mitogen-activated protein kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Differential induction of c-fos, c-jun, and apoptosis in lung epithelial cells exposed to ROS or RNS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Hydrogen peroxide-induced liver cell necrosis is dependent on AP-1 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

[D-Arg1,D-Trp5,7,9,Leu11]substance P: a novel potent inhibitor of signal transduction and growth in vitro and in vivo in small cell lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

[D-Arg1,D-Trp5,7,9,Leu11]Substance P coordinately and reversibly inhibits bombesin- and vasopressin-induced signal transduction pathways in Swiss 3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Inhibition of neuropeptide-stimulated tyrosine phosphorylation and tyrosine kinase activity stimulates apoptosis in small cell lung cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

GTPase-deficient G alpha 16 and G alpha q induce PC12 cell differentiation and persistent activation of cJun NH2-terminal kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Oxidative stress as a mediator of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Diversity in function and regulation of MAP kinase pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Transforming G protein-coupled receptors potently activate JNK (SAPK). Evidence for a divergence from the tyrosine kinase signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Activation of Jun Kinase/Stress-activated Protein Kinase by GTPase-deficient Mutants of Gα12 and Gα13

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Substance P-related antagonists inhibit vasopressin and bombesin but not 5'-3-O-(thio)triphosphate-stimulated inositol phosphate production in Swiss 3T3 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Early events elicited by bombesin and structurally related peptides in quiescent Swiss 3T3 cells. I. Activation of protein kinase C and inhibition of epidermal growth factor binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Effects of bombesin on human small cell lung cancer cells: evidence for a subset of bombesin non-responsive cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Multiple neuropeptides mobilise calcium in small cell lung cancer: effects of vasopressin, bradykinin, cholecystokinin, galanin and neurotensin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P, a potent bombesin antagonist in murine Swiss 3T3 cells, inhibits the growth of human small cell lung cancer cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Inflammatory oedema induced by synergism between calcitonin gene-related peptide (CGRP) and mediators of increased vascular permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Multiple neuropeptides stimulate clonal growth of small cell lung cancer: effects of bradykinin, vasopressin, cholecystokinin, galanin, and neurotensin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Social controls on cell survival and cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

In vitro effects of substance P analogue [D-Arg1, D-Phe5, D-Trp7,9, Leu11] substance P on human tumour and normal cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Growth of small cell lung cancer cells: stimulation by multiple neuropeptides and inhibition by broad spectrum antagonists in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Prostaglandin E2, prostaglandin I2 and the vascular changes of inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

Definitive evidence for hypoxic cells influencing cure in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

5 June 2018

The G-protein G13 but not G12 mediates signaling from lysophosphatidic acid receptor via epidermal growth factor receptor to Rho.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

17 August 2018

Constitutively active Galphaq and Galpha13 trigger apoptosis through different pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

17 August 2018

Differential modulation of bombesin-stimulated phospholipase C beta and mitogen-activated protein kinase activity by [D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363053

17 August 2018

Programmed cell death during regression of the MCF-7 human breast cancer following estrogen ablation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10362111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of receptor-stimulated guanosine 5'-O-(gamma-thio)triphosphate binding by G proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/10362111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the EP-receptor mediating dilatation and potentiation of inflammation in rabbit skin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10362111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suramin analogues as subtype-selective G protein inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10362111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential activation of mitogen-activated protein kinases by nitric oxide-related species

1 reference

https://pubmed.ncbi.nlm.nih.gov/10362111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Galanin, neurotensin, and phorbol esters rapidly stimulate activation of mitogen-activated protein kinase in small cell lung cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10362111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High Levels of Intracellular Bombesin Characterize Human Small-Cell Lung Carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10362111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The impact of chemotherapy on small cell carcinoma of the bronchus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10362111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia/reoxygenation stimulates Jun kinase activity through redox signaling in cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10362111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Jun NH2-terminal kinase regulation of the apoptotic response of small cell lung cancer cells to ultraviolet radiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10362111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Galanin stimulates Ca2+ mobilization, inositol phosphate accumulation, and clonal growth in small cell lung cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10362111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]Substance P acts as a biased agonist toward neuropeptide and chemokine receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6690458

7 January 2021

based on heuristic

inferred from DOI database lookup

Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6690458

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.BJC.6690458

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

ResearchGate publication ID

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