(Q42044812)

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Farnesylcysteine analogues inhibit store-regulated Ca2+ entry in human platelets: evidence for involvement of small GTP-binding proteins and actin cytoskeleton

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727417%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Farnesylcysteine analogues inhibit store-regulated Ca2+ entry in human platelets: evidence for involvement of small GTP-binding proteins and actin cytoskeleton (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727417%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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1 reference

Europe PubMed Central

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5 November 2019

Stewart O. Sage

2

1 reference

Europe PubMed Central

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5 November 2019

author name string

Rosado JA

1

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Europe PubMed Central

15 October 2017

Sage SO

2

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Europe PubMed Central

15 October 2017

language of work or name

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publication date

1 April 2000

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Europe PubMed Central

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5 November 2019

Biochemical Journal

1 reference

Europe PubMed Central

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5 November 2019

347 Pt 1

1 reference

Europe PubMed Central

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5 November 2019

183-192

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727417%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Activation of the small GTPase Ral in platelets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Store depletion and calcium influx

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Role of the cytoskeleton in calcium signaling in NIH 3T3 cells. An intact cytoskeleton is required for agonist-induced [Ca2+]i signaling, but not for capacitative calcium entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Capacitative calcium entry is inhibited in vascular endothelial cells by disruption of cytoskeletal microfilaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Ras activation in platelets after stimulation of the thrombin receptor, thromboxane A2 receptor or protein kinase C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Inhibition of capacitative Ca2+ entry into cells by farnesylcysteine analogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Endosome dynamics regulated by a Rho protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Rho family GTPases: the cytoskeleton and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Protein prenylation: molecular mechanisms and functional consequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

The role of G protein methylation in the function of a geranylgeranylated beta gamma isoform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Protein prenylcysteine analog inhibits agonist-receptor-mediated signal transduction in human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Prenyl group identification of rap2 proteins: a ras superfamily member other than ras that is farnesylated

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Disassembly of the actin network inhibits insulin-dependent stimulation of glucose transport and prevents recruitment of glucose transporters to the plasma membrane.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Selective inhibition of Ras-dependent cell growth by farnesylthiosalisylic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Primaquine, an inhibitor of vesicular transport, blocks the calcium-release-activated current in rat megakaryocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Role of membrane trafficking in plasma membrane solute transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Rapid rate of tubulin dissociation from microtubules in the mitotic spindle in vivo measured by blocking polymerization with colchicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

A new generation of Ca2+ indicators with greatly improved fluorescence properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Receptor-mediated calcium entry in fura-2-loaded human platelets stimulated with ADP and thrombin. Dual-wavelengths studies with Mn2+.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

All ras proteins are polyisoprenylated but only some are palmitoylated

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

'Quantal' Ca2+ release and the control of Ca2+ entry by inositol phosphates--a possible mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Cyclic GMP mediates the agonist-stimulated increase in plasma membrane calcium entry in the pancreatic acinar cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Calcium signaling in human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Methylation and proteolysis are essential for efficient membrane binding of prenylated p21K-ras(B).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Cytochrome P-450 may link intracellular Ca2+ stores with plasma membrane Ca2+ influx

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Capacitative calcium entry revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Post-translational modifications of the C-terminal region of the rho protein are important for its interaction with membranes and the stimulatory and inhibitory GDP/GTP exchange proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Subcellular distribution of the calcium-storing inositol 1,4,5-trisphosphate-sensitive organelle in rat liver. Possible linkage to the plasma membrane through the actin microfilaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Coupling between intracellular Ca2+ stores and the Ca2+ permeability of the plasma membrane. Comparison of the effects of thapsigargin, 2,5-di-(tert-butyl)-1,4-hydroquinone, and cyclopiazonic acid in rat thymic lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Molecular dissection of the secretory pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

The prenylation of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Post-translational processing of rac p21s is important both for their interaction with the GDP/GTP exchange proteins and for their activation of NADPH oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

5 June 2018

Role of [Ca2+]i in "Ca2+ stores depletion-Ca2+ entry coupling' in fibroblasts expressing the rat neurotensin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

17 August 2018

Inhibition of protein prenylation by patulin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

17 August 2018

Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220946

3 November 2018

Translocation of protein kinase C isozymes in thrombin-stimulated human platelets. Correlation with 1,2-diacylglycerol levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rho gene product in human blood platelets. II. Effects of the ADP-ribosylation by botulinum C3 ADP-ribosyltransferase on platelet aggregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ADP- and thapsigargin-evoked Ca2+ entry and protein-tyrosine phosphorylation are inhibited by the tyrosine kinase inhibitors genistein and methyl-2,5-dihydroxycinnamate in fura-2-loaded human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A GTP-dependent step in the activation mechanism of capacitative calcium influx

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of thapsigargin-induced calcium entry by microinjected guanine nucleotide analogues. Evidence for the involvement of a small G-protein in capacitative calcium entry

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro processing of recombinant G protein gamma subunits. Requirements for assembly of an active beta gamma complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanistic studies on human platelet isoprenylated protein methyltransferase: farnesylcysteine analogs block platelet aggregation without inhibiting the methyltransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium store depletion in dimethyl BAPTA-loaded human platelets increases protein tyrosine phosphorylation in the absence of a rise in cytosolic calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incorporation of Rap 1b into the platelet cytoskeleton is dependent on thrombin activation and extracellular calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Are tyrosine phosphorylation of p125(FAK) and paxillin or the small GTP binding protein, rho, needed for CCK-stimulated pancreatic amylase secretion?

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of cyclin-dependent kinase 2 (Cdk2) in growth-stimulated rat astrocytes. Geranylgeranylated Rho small GTPase(s) are essential for the induction of cyclin E gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEK and ERK activation in ras-disabled RBL-2H3 mast cells and novel roles for geranylgeranylated and farnesylated proteins in Fc epsilonRI-mediated signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of interfering with GTP-binding proteins on the activation mechanism of calcium release-activated calcium current

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of actin cytoskeleton in modulation of apical K channel activity in rat collecting duct

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of actin polymerization in blood platelets by cytochalasins

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voltage-gated potassium channels and the control of membrane potential in human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifying the recognition unit for G protein methylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of interactions between transducin alpha/beta gamma-subunits and lipid membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rac-dependent and -independent Pathways Mediate Growth Factor-induced Ca Influx

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of farnesyl and geranylgeranyl methyltransferases prevent beta 2 integrin-induced actin polymerization without affecting beta 2 integrin-induced Ca2+ signaling in neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D3 phosphoinositides and outside-in integrin signaling by glycoprotein IIb-IIIa mediate platelet actin assembly and filopodial extension induced by phorbol 12-myristate 13-acetate

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytosolic and stored calcium antagonistically control tyrosine phosphorylation of specific platelet proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/0264-6021:3470183

1 reference

Europe PubMed Central

15 October 2017

10.1042/BJ3470183

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727417%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727417%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727417%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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