(Q42044958)

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Highly flexible ligand binding pocket of ecdysone receptor: a single amino acid change leads to discrimination between two groups of nonsteroidal ecdysone agonists.

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27 December 2019

Highly flexible ligand binding pocket of ecdysone receptor: a single amino acid change leads to discrimination between two groups of nonsteroidal ecdysone agonists (English)

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27 December 2019

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27 December 2019

Subba Reddy Palli

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27 December 2019

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Mohan B Kumar

1

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27 December 2019

David W Potter

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27 December 2019

Robert E Hormann

3

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27 December 2019

Angela Edwards

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27 December 2019

Howard C Smith

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27 December 2019

Martha A Dipietro

7

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27 December 2019

Mitch Polley

8

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27 December 2019

Michael Lawless

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27 December 2019

Philippa R N Wolohan

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27 December 2019

Damodhar R Kethidi

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23 April 2004

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27 December 2019

Journal of Biological Chemistry

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27 December 2019

279

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27 December 2019

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27 December 2019

27211-27218

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27 December 2019

Ecdysone receptors and their biological actions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403839200

21 January 2018

The Drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403839200

21 January 2018

Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403839200

21 January 2018

Functional ecdysone receptor is the product of EcR and Ultraspiracle genes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403839200

21 January 2018

Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation

1 reference

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21 January 2018

Drosophila tissues with different metamorphic responses to ecdysone express different ecdysone receptor isoforms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403839200

21 January 2018

Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403839200

21 January 2018

Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403839200

21 January 2018

Regulation of invasive cell behavior by taiman, a Drosophila protein related to AIB1, a steroid receptor coactivator amplified in breast cancer

1 reference

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21 January 2018

SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development.

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21 January 2018

New insecticides with ecdysteroidal and juvenile hormone activity

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21 January 2018

The chemical and biological properties of methoxyfenozide, a new insecticidal ecdysteroid agonist

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21 January 2018

Basis for selective action of a synthetic molting hormone agonist, RH-5992 on lepidopteran insects

1 reference

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21 January 2018

Binding mode of ecdysone agonists to the receptor: comparative modeling and docking studies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403839200

21 January 2018

A new model for 20-hydroxyecdysone and dibenzoylhydrazine binding: a homology modeling and docking approach

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403839200

21 January 2018

A single point mutation in ecdysone receptor leads to increased ligand specificity: implications for gene switch applications

1 reference

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21 January 2018

Synthesis and SAR of cis-1-benzoyl-1,2,3,4-tetrahydroquinoline ligands for control of gene expression in ecdysone responsive systems

1 reference

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21 January 2018

Optimization of alpha-acylaminoketone ecdysone agonists for control of gene expression

1 reference

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21 January 2018

Synthesis and SAR of alpha-acylaminoketone ligands for control of gene expression

1 reference

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21 January 2018

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403839200

21 January 2018

Ecdysteroid-dependent regulation of genes in mammalian cells by a Drosophila ecdysone receptor and chimeric transactivators

1 reference

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21 January 2018

High level transactivation by a modified Bombyx ecdysone receptor in mammalian cells without exogenous retinoid X receptor

1 reference

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21 January 2018

Improved ecdysone receptor-based inducible gene regulation system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403839200

21 January 2018

DHR3: a Drosophila steroid receptor homolog

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403839200

21 January 2018

Transcription activation by the ecdysone receptor (EcR/USP): identification of activation functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403839200

21 January 2018

The impact of mammalian gene regulation concepts on functional genomic research, metabolic engineering, and advanced gene therapies

1 reference

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21 January 2018

Threonine on amino acid position 868 in the human androgen receptor is essential for androgen binding specificity and functional activity

1 reference

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21 January 2018

Molecular determinants of differential ligand sensitivities of insect ecdysteroid receptors

1 reference

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21 January 2018

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

1 reference

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21 January 2018

Functionally orthogonal ligand-receptor pairs for the selective regulation of gene expression generated by manipulation of charged residues at the ligand-receptor interface of ER alpha and ER beta

1 reference

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21 January 2018

Artificial regulatory networks and cascades for discrete multilevel transgene control in mammalian cells

1 reference

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21 January 2018

Cloning and developmental expression of the ecdysone receptor gene from the spruce budworm, Choristoneura fumiferana

1 reference

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21 January 2018

The silkmoth homolog of the Drosophila ecdysone receptor (B1 isoform): cloning and analysis of expression during follicular cell differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403839200

21 January 2018

Cloning of an ecdysone receptor homolog from Manduca sexta and the developmental profile of its mRNA in wings

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403839200

21 January 2018

Transcriptional activation of the cloned Heliothis virescens (Lepidoptera) ecdysone receptor (HvEcR) by muristeroneA.

1 reference

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21 January 2018

Mosquito ecdysteroid receptor: analysis of the cDNA and expression during vitellogenesis

1 reference

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21 January 2018

Cloning of a Chironomus tentans cDNA encoding a protein (cEcRH) homologous to the Drosophila melanogaster ecdysteroid receptor (dEcR).

1 reference

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21 January 2018

Cloning of two putative ecdysteroid receptor isoforms from Tenebrio molitor and their developmental expression in the epidermis during metamorphosis

1 reference

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21 January 2018

Isolation of a functional ecdysteroid receptor homologue from the ixodid tick Amblyomma americanum (L.).

1 reference

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21 January 2018

Cloning of crustacean ecdysteroid receptor and retinoid-X receptor gene homologs and elevation of retinoid-X receptor mRNA by retinoic acid

1 reference

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21 January 2018

The structure of the ultraspiracle ligand-binding domain reveals a nuclear receptor locked in an inactive conformation

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M403839200

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27 December 2019

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27 December 2019

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