(Q42047828)

English

The α7 nicotinic ACh receptor agonist compound B and positive allosteric modulator PNU-120596 both alleviate inflammatory hyperalgesia and cytokine release in the rat.

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

The α7 nicotinic ACh receptor agonist compound B and positive allosteric modulator PNU-120596 both alleviate inflammatory hyperalgesia and cytokine release in the rat. (English)

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

0 references

author name string

G Munro

1

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Rr Hansen

2

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Hk Erichsen

3

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Db Timmermann

4

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Jk Christensen

5

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Hh Hansen

6

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

language of work or name

0 references

publication date

1 September 2012

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

167

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

2

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

421-435

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Voltage- and Temperature-Dependent Allosteric Modulation of α7 Nicotinic Receptors by PNU120596.

1 reference

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5 June 2018

Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit

1 reference

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5 June 2018

Animal research: reporting in vivo experiments: the ARRIVE guidelines

1 reference

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5 June 2018

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

1 reference

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Diclofenac: an update on its mechanism of action and safety profile

1 reference

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5 June 2018

Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats

1 reference

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5 June 2018

Physiological concentrations of choline activate native alpha7-containing nicotinic acetylcholine receptors in the presence of PNU-120596 [1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)-urea].

1 reference

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5 June 2018

Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system

1 reference

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Reflex control of immunity

1 reference

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5 June 2018

An allosteric modulator of alpha7 nicotinic receptors, N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea (PNU-120596), causes conformational changes in the extracellular ligand binding domain similar to those caused by acetylcholine

1 reference

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Suppression of complete Freund's adjuvant-induced adjuvant arthritis by cobratoxin

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Mammalian nicotinic acetylcholine receptors: from structure to function

1 reference

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5 June 2018

Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice

1 reference

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Nociceptors are interleukin-1beta sensors

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Comparison of the novel subtype-selective GABAA receptor-positive allosteric modulator NS11394 [3'-[5-(1-hydroxy-1-methyl-ethyl)-benzoimidazol-1-yl]-biphenyl-2-carbonitrile] with diazepam, zolpidem, bretazenil, and gaboxadol in rat models of inflamm

1 reference

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5 June 2018

A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization.

1 reference

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5 June 2018

A cascade of cytokines mediates mechanical inflammatory hypernociception in mice.

1 reference

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Lipopolysaccharide-induced paw edema model for detection of cytokine modulating anti-inflammatory agents

1 reference

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Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation

1 reference

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5 June 2018

Molecular mechanisms of nociception

1 reference

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Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity

1 reference

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Characterization of the analgesic and anti-inflammatory activities of ketorolac and its enantiomers in the rat.

1 reference

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5 June 2018

Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors

1 reference

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Cytokines, nerve growth factor and inflammatory hyperalgesia: the contribution of tumour necrosis factor alpha

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Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence

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Ethical guidelines for investigations of experimental pain in conscious animals

1 reference

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The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia

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Role of α7 nicotinic acetylcholine receptors in regulating tumor necrosis factor-α (TNF-α) as revealed by subtype selective agonists

1 reference

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A question of balance--positive versus negative allosteric modulation of GABA(A) receptor subtypes as a driver of analgesic efficacy in rat models of inflammatory and neuropathic pain.

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Protective effect of alpha7 nAChR: behavioural and morphological features on neuropathy

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Pharmacological effects of nonselective and subtype-selective nicotinic acetylcholine receptor agonists in animal models of persistent pain

1 reference

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Activation of the cholinergic anti-inflammatory system by nicotine attenuates neuroinflammation via suppression of Th1 and Th17 responses

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A randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of ABT-594 in patients with diabetic peripheral neuropathic pain

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The effect of peripherally administered CDP-choline in an acute inflammatory pain model: the role of alpha7 nicotinic acetylcholine receptor

1 reference

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Pharmacological assessment of the rat formalin test utilizing the clinically used analgesic drugs gabapentin, lamotrigine, morphine, duloxetine, tramadol and ibuprofen: influence of low and high formalin concentrations

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The selective nicotinic acetylcholine receptor alpha7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain

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Activation of the alpha7-nicotinic acetylcholine receptor reverses complete freund adjuvant-induced mechanical hyperalgesia in the rat via a central site of action

1 reference

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Behavioural, histological and cytokine responses during hyperalgesia induced by carrageenan injection in the rat tail.

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Cytokine profiles during carrageenan-induced inflammatory hyperalgesia in rat muscle and hind paw.

1 reference

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Diazepam effects on carrageenan-induced inflammatory paw edema in rats: role of nitric oxide

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Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway

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The antinociceptive effects of alpha7 nicotinic agonists in an acute pain model

1 reference

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Time-course of spinal sensitization following carrageenan-induced inflammation in the young rat: a comparative electrophysiological and behavioural study in vitro and in vivo

1 reference

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inferred from PubMed ID database lookup

Physiological evidence that the 'interphase' in the formalin test is due to active inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/22536953

12 December 2020

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1 reference

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1 reference

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based on heuristic

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Identifiers

10.1111/J.1476-5381.2012.02003.X

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

ResearchGate publication ID

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