(Q42062005)

English

Direct effects of IL-4 on mast cells drive their intestinal expansion and increase susceptibility to anaphylaxis in a murine model of food allergy

scientific article published on 14 November 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Direct effects of IL-4 on mast cells drive their intestinal expansion and increase susceptibility to anaphylaxis in a murine model of food allergy (English)

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

0 references

1 reference

based on heuristic

inferred from title

anaphylactic shock

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

O T Burton

1

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

A R Darling

2

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

J S Zhou

3

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

M Noval-Rivas

4

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

T G Jones

5

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

M F Gurish

6

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

T A Chatila

7

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

H C Oettgen

8

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

publication date

14 November 2012

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Mucosal Immunology

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

6

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

4

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

740-750

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

https://scigraph.springernature.com/pub.10.1038/mi.2012.112

0 references

Mast cells orchestrate type 2 immunity to helminths through regulation of tissue-derived cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Intestinal mast cell levels control severity of oral antigen-induced anaphylaxis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

IgE-mediated systemic anaphylaxis and impaired tolerance to food antigens in mice with enhanced IL-4 receptor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

In vivo regulation of the allergic response by the IL-4 receptor alpha chain immunoreceptor tyrosine-based inhibitory motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

IL-4 and TGF-beta 1 counterbalance one another while regulating mast cell homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Endogenous suppression of mast cell development and survival by IL-4 and IL-10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Targeting IL-4/IL-13 signaling to alleviate oral allergen-induced diarrhea

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

The in vivo cytokine capture assay for measurement of cytokine production in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Antigen-independent effects of immunoglobulin E.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Basophils initiate IL-4 production during a memory T-dependent response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Interleukin-4 receptor signaling pathways in asthma pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Interleukin-4- and interleukin-13-mediated host protection against intestinal nematode parasites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Mast cells are required for experimental oral allergen-induced diarrhea

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Targeted inactivation of the IL-4 receptor alpha chain I4R motif promotes allergic airway inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

IL-4 exacerbates anaphylaxis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Role of STAT6 and mast cells in IL-4- and IL-13-induced alterations in murine intestinal epithelial cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

IL-4 induces the proteolytic processing of mast cell STAT6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Proteolytic processing of Stat6 signaling in mast cells as a negative regulatory mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Intestinal mast cell progenitors require CD49dbeta7 (alpha4beta7 integrin) for tissue-specific homing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

The role of Th2 cytokines in mast cell homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Regulation of human intestinal mast cells by stem cell factor and IL-4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Immunopathology of intestinal helminth infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Combined stimulation with the T helper cell type 2 cytokines interleukin (IL)-4 and IL-10 induces mouse mast cell apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Histamine and tryptase levels in patients with acute allergic reactions: An emergency department-based study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Interleukins 4 and 13 increase intestinal epithelial permeability by a phosphatidylinositol 3-kinase pathway. Lack of evidence for STAT 6 involvement.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

The IL-4 receptor: signaling mechanisms and biologic functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

IgE enhances mouse mast cell Fc(epsilon)RI expression in vitro and in vivo: evidence for a novel amplification mechanism in IgE-dependent reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Interleukin 4 as an essential factor for in vitro clonal growth of murine connective tissue-type mast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

T-cell and mast cell lines respond to B-cell stimulatory factor 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Isolation and characterization of a mouse interleukin cDNA clone that expresses B-cell stimulatory factor 1 activities and T-cell- and mast-cell-stimulating activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Characterization of a murine lymphokine distinct from interleukin 2 and interleukin 3 (IL-3) possessing a T-cell growth factor activity and a mast-cell growth factor activity that synergizes with IL-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

5 June 2018

Food allergy among U.S. children: trends in prevalence and hospitalizations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

17 August 2018

Immune sensitization in the skin is enhanced by antigen-independent effects of IgE.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

17 August 2018

IL-4 induces differentiation and expansion of Th2 cytokine-producing eosinophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

17 August 2018

Interleukin-4 elicits apoptosis of developing mast cells via a Stat6-dependent mitochondrial pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3600405

17 August 2018

Trends in pediatric emergency department visits for food-induced anaphylaxis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23149659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of common cytokine receptor gamma chain (gamma(c))- and Jak3-dependent signaling in the proliferation and survival of murine mast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23149659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cofactors are essential for stem cell factor-dependent growth and maturation of mast cell progenitors: comparative effects of interleukin-3 (IL-3), IL-4, IL-10, and fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/23149659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-4-regulated enteropathy in an intestinal nematode infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/23149659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-4-induced priming of human intestinal mast cells for enhanced survival and Th2 cytokine generation is reversible and associated with increased activity of ERK1/2 and c-Fos

1 reference

https://pubmed.ncbi.nlm.nih.gov/23149659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coordinate analysis of murine immune cell surface markers and intracellular phosphoproteins by flow cytometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/23149659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of mouse small intestinal intraepithelial lymphocytes, Peyer's patch, and lamina propria cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23149659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mast cells counteract regulatory T-cell suppression through interleukin-6 and OX40/OX40L axis toward Th17-cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23149659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/MI.2012.112

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

ResearchGate publication ID

0 references

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