(Q42084932)

English

E64 [trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane] analogues as inhibitors of cysteine proteinases: investigation of S2 subsite interactions

scientific article published on April 1994

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

E64 [trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane] analogues as inhibitors of cysteine proteinases: investigation of S2 subsite interactions (English)

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

author name string

B J Gour-Salin

1

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

P Lachance

2

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

M C Magny

3

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

C Plouffe

4

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

R Ménard

5

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

A C Storer

6

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

language of work or name

0 references

publication date

1 April 1994

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Biochemical Journal

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

299 ( Pt 2)

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

389-392

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Tissue sulfhydryl groups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Characterization of cathepsin B specificity by site-directed mutagenesis. Importance of Glu245 in the S2-P2 specificity for arginine and its role in transition state stabilization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Cathepsin B, Cathepsin H, and cathepsin L

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Abnormal increases of lysosomal cysteinine proteinases in rimmed vacuoles in the skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Abnormal expression of lysosomal cysteine proteinases in muscle wasting diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Activation of the intramyofibral autophagic-lysosomal system in muscular dystrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Crystal structure of a papain-E-64 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Cysteinyl proteinases and their selective inactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Localization of cathepsin B in two human lung cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Recent developments in inhibiting cysteine and serine proteases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

A model to explain the pH-dependent specificity of cathepsin B-catalysed hydrolyses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Cooperativity of papain-substrate interaction energies in the S2 to S2' subsites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Collagenolytic cysteine proteinases of bone tissue. Cathepsin B, (pro)cathepsin L and a cathepsin L-like 70 kDa proteinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Relationship between the secretion of cysteine proteinases and their inhibitors and malignant potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Abrogation of the invasion of human bladder tumor cells by using protease inhibitor(s).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Comparison of proteolytic enzyme activity in pulmonary alveolar macrophages and blood leukocytes in smokers and nonsmokers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Binding of chloromethyl ketone substrate analogues to crystalline papain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Inactivation of human α1-proteinase inhibitor by thiol proteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

30 May 2018

Determination of the rate constant of enzyme modification by measuring the substrate reaction in the presence of the modifier.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138284

17 August 2018

An agarose mercurial column for the separation of mercaptopapain and nonmercaptopapain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8172599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Facile synthesis of amino acid and peptide esters under mild conditions via cesium salts

1 reference

https://pubmed.ncbi.nlm.nih.gov/8172599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitions by E-64 derivatives of rat liver cathepsin B and cathepsin L in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/8172599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relaxed and perturbed substrate conformations in enzyme active sites: evidence from multichannel resonance raman spectra

1 reference

https://pubmed.ncbi.nlm.nih.gov/8172599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo and in vitro evidence for the involvement of cysteine proteinases in bone resorption

1 reference

https://pubmed.ncbi.nlm.nih.gov/8172599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Engineering of papain: selective alteration of substrate specificity by site-directed mutagenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8172599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterisation of cysteine proteinases from human osteoclastomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/8172599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epoxysuccinyl dipeptides as selective inhibitors of cathepsin B

1 reference

https://pubmed.ncbi.nlm.nih.gov/8172599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cysteine proteinase cathepsin L expression correlates closely with the metastatic potential of H-ras-transformed murine fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/8172599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The importance of Val-157 hydrophobic interaction for papain inhibitory activity of an epoxysuccinyl amino acid derivative. A structure-activity relationship based on the crystal structure of the papain-E-64-c complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/8172599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel epoxysuccinyl peptides. Selective inhibitors of cathepsin B, in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/8172599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ2990389

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

ResearchGate publication ID

0 references

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