(Q42091159)

English

Microarray analysis identifies changes in inflammatory gene expression in response to amyloid-beta stimulation of cultured human retinal pigment epithelial cells

scientific article published on 24 September 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Microarray analysis identifies changes in inflammatory gene expression in response to amyloid-beta stimulation of cultured human retinal pigment epithelial cells (English)

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

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author name string

Khaliq H Kurji

1

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Jing Z Cui

2

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Tony Lin

3

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

David Harriman

4

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Shiv S Prasad

5

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Ljuba Kojic

6

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Joanne A Matsubara

7

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Europe PubMed Central

PMC publication ID

16 October 2017

language of work or name

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publication date

24 September 2009

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Investigative Ophthalmology Visual Science

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Europe PubMed Central

PMC publication ID

16 October 2017

51

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

2

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

1151-1163

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Amyloid-beta(1-42) alters structure and function of retinal pigmented epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Variation near complement factor I is associated with risk of advanced AMD

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Amyloid-beta deposits lead to retinal degeneration in a mouse model of Alzheimer disease

1 reference

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Altered function of factor I caused by amyloid beta: implication for pathogenesis of age-related macular degeneration from Drusen

1 reference

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29 May 2018

Oxidative inactivation of the proteasome in retinal pigment epithelial cells. A potential link between oxidative stress and up-regulation of interleukin-8.

1 reference

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29 May 2018

Complement-associated deposits in the human retina

1 reference

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29 May 2018

Intracellular zinc homeostasis in leukocyte subsets is regulated by different expression of zinc exporters ZnT-1 to ZnT-9.

1 reference

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Broad but distinct role of pregnane x receptor on the expression of individual cytochrome p450s in human hepatocytes

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29 May 2018

Pro-inflammatory cytokines increase reactive oxygen species through mitochondria and NADPH oxidase in cultured RPE cells

1 reference

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29 May 2018

Gene expression and promoter methylation of the XIAP-associated Factor 1 in renal cell carcinomas: correlations with pathology and outcome

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29 May 2018

Silencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-beta

1 reference

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29 May 2018

Synthesis of complement factor H by retinal pigment epithelial cells is down-regulated by oxidized photoreceptor outer segments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo

1 reference

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29 May 2018

Age-related macular degeneration (AMD): pathogenesis and therapy

1 reference

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29 May 2018

The role of inflammation in the pathogenesis of age-related macular degeneration

1 reference

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29 May 2018

Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

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29 May 2018

The potential role of amyloid beta in the pathogenesis of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Evidence for an inflammatory process in age-related macular degeneration gains new support

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Association study of detoxification genes in age related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Complement factor H polymorphism in age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Complement factor H polymorphism and age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Complement factor H variant increases the risk of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Inflammation and the degenerative diseases of aging

1 reference

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29 May 2018

Pathogenesis of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Interleukin-1beta stimulates IL-8 expression through MAP kinase and ROS signaling in human gastric carcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Anti-angiogenic effects of somatostatin receptor subtype 2 on human pancreatic cancer xenografts

1 reference

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29 May 2018

Current concepts in the pathogenesis of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Characterization of beta amyloid assemblies in drusen: the deposits associated with aging and age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

1 reference

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29 May 2018

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

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29 May 2018

Neutralization of TRAIL death pathway protects human neuronal cell line from beta-amyloid toxicity

1 reference

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29 May 2018

The immunopathogenesis of sepsis

1 reference

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29 May 2018

Genomic DNA standards for gene expression profiling in Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

A role for local inflammation in the formation of drusen in the aging eye.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

The Alzheimer's A beta -peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Identification of X-linked inhibitor of apoptosis-associated factor-1 as an interferon-stimulated gene that augments TRAIL Apo2L-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Complement activation and inflammatory processes in Drusen formation and age related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Identification of XAF1 as an antagonist of XIAP anti-Caspase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Proteasome-mediated regulation of interleukin-1beta turnover and export in human monocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Inflammation and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Somatostatin receptor gene expression in neuroblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

The interferon-induced gene ISG12 is regulated by various cytokines as the gene 6-16 in human cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Drusen in age-related macular degeneration: pathogenesis, natural course, and laser photocoagulation-induced regression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Somatostatin and its receptor family

1 reference

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29 May 2018

Role of NF-kappaB-mediated interleukin-8 expression in intraocular neovascularization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Polarized secretion of IL-6 and IL-8 by human retinal pigment epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Neuronal expression of mRNAs for complement proteins of the classical pathway in Alzheimer brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Redox regulation of NF-kappa B activation

1 reference

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29 May 2018

Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Monocyte-induced cytokine expression in cultured human retinal pigment epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Activation of the classical complement pathway in brain tissue of Alzheimer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Macrophages related to Bruch's membrane in age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Neutrophil chemotactic factor (IL-8) gene expression by cytokine-treated retinal pigment epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Expression of interleukin-1 alpha, interleukin-1 beta, and an interleukin-1 receptor antagonist in human retinal pigment epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

29 May 2018

Interleukin gene polymorphisms in age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

17 August 2018

Transforming growth factor beta2-induced myofibroblastic differentiation of human retinal pigment epithelial cells: regulation by extracellular matrix proteins and hepatocyte growth factor

1 reference

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17 August 2018

The catalytically active serine protease domain of human complement factor I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

17 August 2018

Altered gene expression of angiogenic factors induced by calcium-mediated dissociation of retinal pigment epithelial cells

1 reference

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Somatostatin inhibits IGF-1 mediated induction of VEGF in human retinal pigment epithelial cells

1 reference

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17 August 2018

Differential gene expression of early and late passage retinal pigment epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

17 August 2018

Differential involvement of phosphoinositide 3-kinase/Akt in human RPE MCP-1 and IL-8 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

17 August 2018

Self-assembly of Abeta(1-42) into globular neurotoxins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

17 August 2018

Drusen-Associated Degeneration in the Retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

17 August 2018

Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

17 August 2018

Induction of angiogenic cytokine expression in cultured RPE by ingestion of oxidized photoreceptor outer segments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

17 August 2018

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

17 August 2018

Vaccination with soluble Abeta oligomers generates toxicity-neutralizing antibodies.

1 reference

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17 August 2018

Interaction of vaccinia virus complement control protein with human complement proteins: factor I-mediated degradation of C3b to iC3b1 inactivates the alternative complement pathway.

1 reference

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17 August 2018

Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

17 August 2018

Retinal pigment epithelial cells produce interleukin-1 beta and granulocyte-macrophage colony-stimulating factor in response to interleukin-1 alpha.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3947389

17 August 2018

HERC5, a HECT E3 ubiquitin ligase tightly regulated in LPS activated endothelial cells

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https://pubmed.ncbi.nlm.nih.gov/19797223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/19797223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antiviral cytomegalovirus inducible gene 5/viperin is expressed in atherosclerosis and regulated by proinflammatory agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/19797223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress modulates complement factor H expression in retinal pigmented epithelial cells by acetylation of FOXO3

1 reference

https://pubmed.ncbi.nlm.nih.gov/19797223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19797223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expanding extracellular zinc beyond levels reflecting the albumin-bound plasma zinc pool potentiates the capability of IL-1beta, IL-18, and IL-12 to Act as IFN-gamma-inducing factors on PBMC

1 reference

https://pubmed.ncbi.nlm.nih.gov/19797223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-competition between vasoactive intestinal peptide and somatostatin for binding to tumor cell membrane receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19797223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines in proliferative diabetic retinopathy and proliferative vitreoretinopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19797223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nanometer-scale structure of amyloid-beta visualized by atomic force microscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19797223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of a somatostatin analog (octreotide acetate) on the growth of retinal pigment epithelial cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/19797223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-7 (IL-7) induces retinal pigment epithelial cell MCP-1 and IL-8

1 reference

https://pubmed.ncbi.nlm.nih.gov/19797223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatostatin receptor 2A expression in choroidal neovascularization secondary to age-related macular degeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19797223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1167/IOVS.09-3622

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

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